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Tapsentan

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Identification
Molecular formula
C17H25N3O3
CAS number
.null,
IUPAC name
3-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]-1,3-benzoxazol-2-one
State
State

Solid at room temperature.

Melting point (Celsius)
132.50
Melting point (Kelvin)
405.65
Boiling point (Celsius)
388.76
Boiling point (Kelvin)
661.91
General information
Molecular weight
321.41g/mol
Molar mass
321.3800g/mol
Density
1.2850g/cm3
Appearence

Tapsentan typically appears as a white to off-white crystalline solid.

Comment on solubility

Solubility of 3-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]-1,3-benzoxazol-2-one

The solubility of 3-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]-1,3-benzoxazol-2-one can be influenced by several factors. Understanding these factors is crucial for practical applications, especially in pharmaceuticals and chemical formulations. Here are some key points to consider:

  • Solvent Polarity: The solubility is generally higher in polar solvents due to the presence of hydroxyl (-OH) groups that can form hydrogen bonds.
  • pH Levels: The solubility may also vary with the pH of the solution. Compounds with amine functionalities can become charged in more acidic conditions, potentially increasing solubility.
  • Temperature Influence: Increasing temperature typically enhances the solubility of many organic compounds in solvents due to greater kinetic energy overcoming intermolecular interactions.
  • Complex Formations: The formation of aggregates or complexes with co-solvents can further modify solubility properties.

In summary, the solubility of this compound can be optimized by carefully selecting a solvent system and adjusting conditions to favor solvation. As always, empirical testing remains one of the most reliable methods for determining specific solubility parameters.

Interesting facts

Interesting Facts about 3-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]-1,3-benzoxazol-2-one

This fascinating compound, known for its structural complexity and biochemical applications, represents an intriguing blend of organic chemistry and pharmacological significance. Here are some captivating aspects:

  • Structural Versatility: The compound features a benzoxazole core, which is a fused ring structure commonly found in numerous biologically active molecules. This core is often associated with properties such as antibacterial, antiviral, and anticancer activities.
  • Biological Relevance: The presence of the piperazine ring is significant in medicinal chemistry. Piperazine derivatives are known for their ability to interact with various receptor sites in the human body, making them valuable in the design of psychoactive and therapeutic agents.
  • Hydroxyethyl moiety: The incorporation of the 2-hydroxyethyl group enhances solubility and can help in modulating the pharmacokinetic properties of the molecule, which is crucial for drug design and efficacy.
  • Potential Applications: Due to its unique structure, this compound may have applications in the fields of neuropharmacology and medicinal chemistry, potentially offering new avenues for the treatment of various neurological disorders.
  • Research Implications: Ongoing studies around related compounds continue to explore their functionalities, paving the way for novel therapeutic strategies. As the demand for innovative medical solutions rises, understanding compounds like this one is essential.

In conclusion, 3-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]-1,3-benzoxazol-2-one is more than just a chemical substance; it is a promising entity that illustrates the synergy between organic chemistry and pharmacology. The exploration of such compounds holds the key to unlocking new potential in medicine!

Synonyms
14733-76-7
BRN 1223129
2-BENZOXAZOLINONE, 3-(3-(4-(2-HYDROXYETHYL)-1-PIPERAZINYL)PROPYL)-
DTXSID20163681
3-(3-(4-(2-Hydroxyethyl)-1-piperazinyl)propyl)-2-benzoxazolinone
DTXCID1086172
3-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]-1,3-benzoxazol-2-one
3-[3-[4-(2-Hydroxyethyl)piperazin-1-yl]propyl]benzoxazol-2(3H)-one
AKOS033008583
Z1051110734