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Memantine hydrochloride

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Identification
Molecular formula
C12H23N3 · 2HCl
CAS number
41100-52-1
IUPAC name
3-(3-amino-1-adamantyl)adamantan-1-amine;dihydrochloride
State
State

At room temperature, memantine hydrochloride is in a solid state. It is typically used in the form of tablets or capsules in pharmaceutical applications.

Melting point (Celsius)
292.00
Melting point (Kelvin)
565.15
Boiling point (Celsius)
225.00
Boiling point (Kelvin)
498.15
General information
Molecular weight
215.81g/mol
Molar mass
215.8130g/mol
Density
1.2386g/cm3
Appearence

Memantine hydrochloride is a white to off-white crystalline powder. It is usually odorless and may appear as a fine, fluffy solid.

Comment on solubility

Solubility of 3-(3-amino-1-adamantyl)adamantan-1-amine; dihydrochloride

The compound 3-(3-amino-1-adamantyl)adamantan-1-amine; dihydrochloride exhibits interesting solubility characteristics that can be influenced by various factors. Generally speaking, the solubility of this dihydrochloride salt can be highlighted as follows:

  • Solvent Type: The compound is known to be more soluble in polar solvents like water and ethanol. This is often due to the presence of the two hydrochloride groups, which enhance hydrogen bonding with solvent molecules.
  • Hydrochloride Form: As a salt, its solubility tends to be elevated compared to its free base counterpart. This increase in solubility in aqueous solutions is crucial for biological applications.
  • Temperature Effects: Like many ionic compounds, the solubility may increase with temperature. Therefore, it is beneficial to consider solubility tests at elevated temperatures when preparing solutions.
  • pH Dependence: The solubility can also depend on the pH of the solution. Lower pH environments (more acidic) typically improve solubility for compounds like this, which can protonate more effectively.

Overall, when assessing the solubility of 3-(3-amino-1-adamantyl)adamantan-1-amine; dihydrochloride, it is essential to consider these variables to achieve optimal dissolving conditions. As the saying goes, "the solubility of a compound is critical in determining its practical applications."

Interesting facts

Interesting Facts About 3-(3-amino-1-adamantyl)adamantan-1-amine Dihydrochloride

This intriguing compound, with a complex structure, is a member of the adamantane family, known for its unique cage-like configuration. Here are some fascinating insights about its characteristics and potential applications:

  • Unique Structure: The adamantane framework provides exceptional stability due to its three-dimensional geometry, which has made it a notable subject in medicinal chemistry.
  • Biological Relevance: The presence of amino groups in its structure may enable this compound to interact with biological systems. Such interactions could lead to significant pharmacological activities.
  • Potential in Drug Development: Compounds featuring adamantane structures are often explored in the development of antiviral and anti-cancer agents. Their ability to modify biological pathways could lead to innovative therapeutic strategies.
  • Synthetic Chemistry: Chemists are often fascinated by the synthetic routes used to create such compounds. The creation of 3-(3-amino-1-adamantyl)adamantan-1-amine dihydrochloride likely involves intricate multi-step synthesis, showcasing the creativity and skill required in modern organic chemistry.
  • Research Opportunities: Due to its novel properties, this compound presents exciting opportunities for further research. Investigating its interaction with various receptors and enzymatic pathways could lead to new discoveries.

As noted by chemist John M. McGowan, "The synthesis and study of adamantane derivatives is like unveiling the hidden gems of molecular architecture." This statement encapsulates the spirit of exploration prevalent in the field of chemical research.

In summary, 3-(3-amino-1-adamantyl)adamantan-1-amine dihydrochloride serves as a reminder of the complexities and potential that lie within seemingly simple organic compounds. It is a compound that bridges the realms of synthetic chemistry and biological science, inviting both researchers and students to delve deeper into its mysteries.

Synonyms
18392-94-4
1,1'-BIADAMANTANE-3-3'-DIAMINE, DIHYDROCHLORIDE
3-(3-amino-1-adamantyl)adamantan-1-amine;dihydrochloride
1,1'-Biadamantane-3-3'-diamine dihydrochloride
1,1#39-Biadamantane-3-3#39-diamine dihydrochloride
DTXSID30939773
3,3'-diamino-1,1'-biadamantyl dihydrochloride
[1,1'-Bi(tricyclo[3.3.1.1~3,7~]decane)]-3,3'-diamine--hydrogen chloride (1/2)