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Iodoquinol

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Identification
Molecular formula
C9H6I3NO2
CAS number
132-33-2
IUPAC name
3-(3-amino-2,4,6-triiodo-phenyl)propanoic acid
State
State

At room temperature, Iodoquinol is in a solid state. It maintains its stability when stored properly in a cool, dry place, away from light and moisture.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
613.97g/mol
Molar mass
613.9690g/mol
Density
3.3020g/cm3
Appearence

Iodoquinol typically appears as a white to slightly yellow crystalline powder. Its crystalline nature often gives it a glossy or shiny finish, depending on the crystal size and form. The color may vary slightly if impurities are present, tending towards a more yellow hue in such cases.

Comment on solubility

Solubility of 3-(3-amino-2,4,6-triiodo-phenyl)propanoic acid

The solubility of 3-(3-amino-2,4,6-triiodo-phenyl)propanoic acid is influenced by its complex molecular structure, which contains multiple iodine substituents. Here are some key points to consider:

  • Water Solubility: Compounds with significant iodine content often exhibit low solubility in water due to their hydrophobic character. The presence of iodine can hinder the molecule's ability to interact with water molecules.
  • Solvent Compatibility: This compound may be more soluble in organic solvents such as dimethyl sulfoxide (DMSO), ethanol, or other polar organic solvents, making solvent choice critical for laboratory applications.
  • pH Influence: The acidic nature of the propanoic acid moiety suggests that solubility may vary with pH, potentially becoming more soluble in basic conditions where the carboxylic acid can deprotonate.
  • Structural Influence: The presence of the amino group might also enhance solubility to some extent by providing sites for hydrogen bonding, especially in polar solvents, but this may not be sufficient to overcome the effects of the bulky iodine groups.

In conclusion, while the solubility of 3-(3-amino-2,4,6-triiodo-phenyl)propanoic acid may present challenges in certain solvents, it remains essential to choose the right solvent and conditions to optimize its solubility properties. Understanding these key factors will allow for effective utilization in various chemical processes.

Interesting facts

Interesting Facts about 3-(3-amino-2,4,6-triiodo-phenyl)propanoic Acid

3-(3-amino-2,4,6-triiodo-phenyl)propanoic acid is a fascinating compound that showcases the intriguing interplay between amino acids and halogenated phenyl groups. Here are some compelling details:

  • Structure and Composition: This compound is characterized by the presence of a propanoic acid backbone linked to a highly substituted phenyl ring. The incorporation of three iodine atoms into the aromatic system creates unique electronic properties that can influence reactivity and biological activity.
  • Biological Significance: The amino group in the structure can confer essential roles in biological systems. Compounds like this have potential applications in pharmaceuticals, particularly in the design of *radiolabeled molecules* for medical imaging.
  • Research Applications: Due to its iodine content, this compound may be investigated in the field of *radiochemistry*. Iodine isotopes can be used as tracers in metabolic studies or in therapies for certain types of cancer.
  • Halogen Effects: The presence of halogens like iodine often alters the physical and chemical properties of organic compounds. This could affect properties such as *lipophilicity* and *biological activity*, making it a topic of interest in medicinal chemistry.
  • Important Derivatives: The structural framework of 3-(3-amino-2,4,6-triiodo-phenyl)propanoic acid can lead to the formation of various derivatives that might act as bioactive compounds, further enhancing its relevance in pharmacology.

In conclusion, 3-(3-amino-2,4,6-triiodo-phenyl)propanoic acid represents a fascinating intersection of structure, function, and application, inspiring ongoing research in various scientific fields. As chemists explore its potential, this compound could pave the way for innovative therapeutic solutions.

Synonyms
1206-91-3
3-(3-amino-2,4,6-triiodophenyl)propanoic acid
3-(3-AMINO-2,4,6-TRIIODOPHENYL)PROPIONIC ACID
HYDROCINNAMIC ACID, 3-AMINO-2,4,6-TRIIODO-
Benzenepropanoic acid,3-amino-2,4,6-triiodo-
3-Amino-2,4,6-triiodohydrocinnamic acid
WIN 4837
BRN 2133556
Benzenepropanoic acid, 3-amino-2,4,6-triiodo-
beta-(2,4,6-Trijod-3-aminophenyl)-propionsaeure [German]
beta-(2,4,6-Trijod-3-aminophenyl)-propionsaeure
4-14-00-01531 (Beilstein Handbook Reference)
CHEMBL48447
SCHEMBL9696076
DTXSID10152928
NS00023928
Beta-(3-Amino-2,4,6-triiodophenyl)propionic acid