3-(3-bromo-4-butoxyphenyl)prop-2-enehydroxamic acid

Identification

Molecular formula

C₁₃H₁₆BrNO₃

CAS number

Not available

IUPAC name

3-(3-bromo-4-butoxy-phenyl)prop-2-enehydroxamic acid

State

At room temperature, 3-(3-bromo-4-butoxyphenyl)prop-2-enehydroxamic acid is in a solid state. Its stability and physical properties make it suitable for use in various chemical synthesis applications, particularly where specific aromatic structures are required.

Melting point (Celsius)

130.00

Melting point (Kelvin)

403.15

Boiling point (Celsius)

320.00

Boiling point (Kelvin)

593.15

General information

Molecular weight

316.14g/mol

Molar mass

316.1410g/mol

Density

1.4500g/cm³

Appearence

3-(3-bromo-4-butoxyphenyl)prop-2-enehydroxamic acid typically appears as a crystalline solid. The coloration can vary depending on purity from off-white to light brown. It is often stored in airtight containers to prevent moisture uptake, particularly if it is hygroscopic in nature.

Comment on solubility

Solubility of 3-(3-bromo-4-butoxy-phenyl)prop-2-enehydroxamic acid

The solubility of 3-(3-bromo-4-butoxy-phenyl)prop-2-enehydroxamic acid is influenced by its unique chemical structure, which includes both hydrophobic and hydrophilic regions. This compound features a hydroxamic acid group that generally exhibits moderate solubility in water due to its ability to form hydrogen bonds.

When considering the overall solubility of this compound, the following points are important:

Hydrophobic Regions: The presence of the butoxy group can hinder solubility in polar solvents like water, as these regions prefer non-polar environments.
Hydrophilic Sites: The hydroxamic acid moiety contributes to potential solubility in aqueous solutions, which may promote interactions with water molecules.
Solvent Interaction: The solubility can also vary significantly based on the solvent used. Organic solvents such as ethanol and dimethyl sulfoxide (DMSO) are likely to enhance solubility due to their compatibility with the compound’s structure.

In practice, **the solvent choice is crucial** for improving the solubility of this compound and achieving optimal conditions for its application. Experimentation with various temperatures and solvent systems may yield favorable solubility conditions, allowing for better utilization in chemical reactions or formulations.

Interesting facts

Interesting Facts about 3-(3-Bromo-4-butoxy-phenyl)prop-2-enehydroxamic Acid

3-(3-Bromo-4-butoxy-phenyl)prop-2-enehydroxamic acid is a fascinating compound that serves a variety of purposes in the field of chemistry and pharmaceuticals. Here are some engaging facts about this intriguing compound:

Functional Group Diversity: This compound features a remarkable array of functional groups, including a hydroxamic acid moiety. Hydroxamic acids are known for their ability to chelate metal ions, making them valuable in medicinal chemistry.
Anticancer Research: Compounds similar to 3-(3-bromo-4-butoxy-phenyl)prop-2-enehydroxamic acid have been investigated for their potential anticancer properties. Their structure can interact with enzymes involved in cancer progression.
Structure-Activity Relationship (SAR): The specific substitutions on the phenyl ring in this compound, such as the bromine and butoxy groups, provide interesting insights into how changes in molecular structure can affect biological activity.
Role in Organic Synthesis: This compound can be utilized as a key intermediate in organic synthesis processes, making it a valuable building block for the development of more complex molecules.
Potential Applications: Beyond its medicinal applications, derivatives of this compound may find use in material science, particularly in the development of polymers and coatings, due to their unique chemical properties.

As a student or scientist delving into the world of organic chemistry, investigating the properties and applications of compounds like 3-(3-bromo-4-butoxy-phenyl)prop-2-enehydroxamic acid can lead to exciting discoveries and innovations in chemical research.