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3-(3-chlorophenyl)prop-2-ynoic acid

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Identification
Molecular formula
C9H5ClO2
CAS number
18919-98-3
IUPAC name
3-(3-chlorophenyl)prop-2-ynoic acid
State
State

At room temperature, 3-(3-chlorophenyl)prop-2-ynoic acid is a solid.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
180.57g/mol
Molar mass
180.5730g/mol
Density
1.3567g/cm3
Appearence

3-(3-Chlorophenyl)prop-2-ynoic acid is a crystalline solid that appears as white to off-white crystals or powder. It is usually odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 3-(3-chlorophenyl)prop-2-ynoic acid

3-(3-chlorophenyl)prop-2-ynoic acid, with its intriguing chemical structure, exhibits certain solubility characteristics that are noteworthy.

  • Solvent Compatibility: This compound is generally soluble in organic solvents such as ethanol, acetone, and dimethyl sulfoxide (DMSO).
  • Water Solubility: Its solubility in water is limited due to its hydrophobic aromatic ring structure, which can inhibit interaction with polar solvents.
  • Effect of pH: The presence of the carboxylic acid group may enhance solubility in basic solutions, as it can deprotonate, forming a more soluble carboxylate ion.

As a general note, the solubility of this compound may be affected by various factors, including temperature, concentration, and the presence of other solutes. As effectively summarized, "Solubility is a multifaceted property influenced by both chemical structure and environmental conditions." Understanding these nuances is essential for applications in chemical synthesis and pharmaceuticals.

Interesting facts

Interesting Facts about 3-(3-Chlorophenyl)prop-2-ynoic Acid

3-(3-Chlorophenyl)prop-2-ynoic acid, often referred to as a member of the propenoic acid family, presents a fascinating combination of chemical properties and applications. This compound contains both a phenyl ring and an alkyne functional group, which enriches its potential use in various fields including organic synthesis and medicinal chemistry.

Key Features

  • Versatile Intermediate: This compound can serve as an intermediate in the synthesis of more complex molecules, making it a valuable building block in organic chemistry.
  • Biological Activity: Research has suggested that compounds containing similar structures can exhibit significant biological activity, including anticancer and antimicrobial properties.
  • Functionalization Potential: The presence of the alkyne group provides numerous opportunities for further reactions, such as cycloadditions and cross-coupling reactions.

Applications

Due to its unique structure, 3-(3-chlorophenyl)prop-2-ynoic acid can be applied in various domains, including:

  • Pharmaceuticals: The possibility of exploring its derivatives in drug development for targeted therapies.
  • Material Science: Its ability to potentially serve as a precursor for polymeric materials.
  • Agricultural Chemistry: Investigating its use in creating effective agrochemicals for pest control.

As chemistry students and researchers continue to explore the vast possibilities of such compounds, it remains vital to stay updated on advancements and novel applications. The synthesis and study of 3-(3-chlorophenyl)prop-2-ynoic acid not only enhance our understanding of chemical interactions but also contribute to discoveries that could lead to groundbreaking solutions in science.

Synonyms
3-(3-Chlorophenyl)propiolic acid
7396-28-3
3-(3-CHLOROPHENYL)-2-PROPYNOIC ACID
Propiolic acid, (m-chlorophenyl)-
HSDB 2674
2-Propynoic acid, 3-(3-chlorophenyl)-
Propynoic acid, (3-chlorophenyl)-
UNII-2N265Q95PV
2N265Q95PV
NSC 408175
NSC-408175
DTXSID90224692
3-(3-CHLOROPHENYL)-2-PROPYNOIC ACID [HSDB]
Propiolic acid, (mchlorophenyl)
Propynoic acid, (3chlorophenyl)
DTXCID20147183
2Propynoic acid, 3(3chlorophenyl)
Propiolic acid, (m-chlorophenyl)-(8CI)
2-Propynoic acid, 3-(3-chlorophenyl)-(9CI)
3-(3-chlorophenyl)prop-2-ynoic acid
(3-chlorophenyl)propiolic acid
MFCD14707279
SCHEMBL670363
3-(3-Chlorophenyl)propiolicacid
FRTZPNZKFMZQDR-UHFFFAOYSA-N
3-(3-chloro-phenyl)propiolic acid
3-(3-chlorophenyl)-propiolic acid
HAA39628
NSC408175
AKOS012949359
NS-01579
CS-0122131
E81466
EN300-130510
Q27255032
Z1143242523