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Mitoxantrone

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Identification
Molecular formula
C22H28N4O6
CAS number
65271-80-9
IUPAC name
3-[3-(dimethylamino)propyl]-12-azatricyclo[4.4.3.01,6]trideca-3,8-diene-11,13-dione
State
State

Mitoxantrone is typically found as a solid at room temperature. When it is prepared for medical use, it is often in liquid form as a solution for injection.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
230.00
Boiling point (Kelvin)
503.15
General information
Molecular weight
517.45g/mol
Molar mass
517.4250g/mol
Density
1.0347g/cm3
Appearence

Mitoxantrone is a dark blue crystalline solid. It is commonly available in its hydrochloride salt form, which can appear as a deep blue powder. To differentiate in solutions, it appears deep blue-green when dissolved.

Comment on solubility

Solubility of 3-[3-(dimethylamino)propyl]-12-azatricyclo[4.4.3.01,6]trideca-3,8-diene-11,13-dione

The solubility of the compound 3-[3-(dimethylamino)propyl]-12-azatricyclo[4.4.3.01,6]trideca-3,8-diene-11,13-dione can be influenced by various factors due to its unique structural features. Here are some key points to consider:

  • The presence of the dimethylamino group typically enhances solubility in polar solvents due to its ability to form hydrogen bonds.
  • The overall hydrophobic nature of the tricyclic structure may limit solubility in water, though it may still be soluble in organic solvents.
  • This compound is likely more soluble in solvents such as ethanol, methanol, or dimethyl sulfoxide (DMSO) compared to water.
  • Factors affecting solubility include temperature, pH, and ionic strength of the solution.

In conclusion, while the compound presents potential for solubility in certain organic solvents, its overall solubility profile will depend on the environmental conditions and specific solvent interactions.

Interesting facts

Interesting Facts about 3-[3-(dimethylamino)propyl]-12-azatricyclo[4.4.3.01,6]trideca-3,8-diene-11,13-dione

This intriguing compound belongs to the class of azatricyclo compounds, which are known for their unique structural characteristics and biological activities. Here are some noteworthy points about this remarkable molecule:

  • Complex Structure: The compound features a tricyclic structure that incorporates an azatricycle, meaning it contains a nitrogen atom within its rings, significantly impacting its chemical properties and reactivity.
  • Potential Biological Activities: Compounds with similar structures to this one have been studied for their potential pharmaceutical applications, including anti-cancer and anti-inflammatory properties.
  • Dimethylamino Group Influence: The presence of the dimethylamino group can enhance solubility and bioavailability, making it an essential functional group in medicinal chemistry.
  • Research Opportunities: This compound provides an excellent platform for researchers interested in exploring new ways to optimize drug design and synthesis. Its structural complexity presents challenges that can lead to valuable insights in organic synthesis.
  • Applications in Chemistry: Besides potential medicinal uses, compounds similar to this one are often utilized as intermediates in synthesizing other chemical entities, paving the way for innovative materials and chemicals.

As you delve deeper into the world of this compound, you will find that its multifaceted nature and potential for various applications make it a significant subject of study in modern chemistry. Its exploration not only contributes to our understanding of similar compounds but also opens doors to innovative research avenues in drug development and material science.

Synonyms
BRN 1541926
16609-47-5
N-(3-(Dimethylamino)propyl)-1,4,5,8-tetrahydro-4a,8a-naphthalenedicarboximide
4a,8a-Naphthalenedicarboximide, 1,4,5,8-tetrahydro-N-(3-(dimethylamino)propyl)-
4a,8a-NAPHTHALENEDICARBOXIMIDE, N-(3-(DIMETHYLAMINO)PROPYL)-1,4,5,8-TETRAHYDRO-
3-[3-(Dimethylamino)propyl]-12-azatricyclo[4.4.3.01,6]trideca-3,8-diene-11,13-dione
DTXSID00937165
3-[3-(Dimethylamino)propyl]-9-hydroxy-1,4,5,8-tetrahydro-4a,8a-(methanoazenometheno)naphthalen-11-one