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Epirubicin

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Identification
Molecular formula
C27H29NO11
CAS number
56390-09-1
IUPAC name
[3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate
State
State

At room temperature, Epirubicin is typically found as a crystalline solid. It is commonly available in the form of its hydrochloride salt.

Melting point (Celsius)
209.00
Melting point (Kelvin)
482.15
Boiling point (Celsius)
488.78
Boiling point (Kelvin)
761.93
General information
Molecular weight
579.99g/mol
Molar mass
579.9930g/mol
Density
1.2870g/cm3
Appearence

Epirubicin hydrochloride appears as a red-orange, crystalline powder.

Comment on solubility

Solubility Overview

The compound 3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate is characterized by its complex molecular structure, which influences its solubility profile significantly.

Factors Affecting Solubility

Several factors can impact the solubility of this compound, including:

  • Molecular Structure: The existence of various functional groups such as amides and hydroxyl can enhance solubility in polar solvents.
  • Hydrophobic Regions: The alkyl chain (hexyl group) contributes to hydrophobic characteristics, potentially reducing solubility in water.
  • pH Dependent Solubility: The presence of acidic and basic functional groups suggests that solubility may vary with changes in pH.

Possible Solubility Behavior

It can be anticipated that:

  • In polar solvents like water, this compound may exhibit limited solubility due to its hydrophobic characteristics.
  • Conversely, solvents with stronger non-polar characteristics might improve the solubility of the hexyl group.
  • This compound may show enhanced solubility in organic solvents such as acetone or ethanol, where both the polar and non-polar aspects of its structure can be effectively utilized.

Ultimately, understanding the solubility of 3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate requires considering its unique structural features and how they interact with various solvents, making empirical solubility testing essential.

Interesting facts

Interesting Facts about [3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate

This compound, with its intricate structure, showcases the fascinating interplay between synthetic chemistry and biological application. Here are some engaging aspects of this compound that draw the attention of scientists and students alike:

  • Complex Structure: The compound features multiple functional groups, including amides and dioxo frameworks, which can present unique reactivity and properties.
  • Potential Biological Activity: The presence of the 3-formamido-2-hydroxy-benzoyl moiety suggests potential biological applications, as similar structures are often explored for their pharmacological properties.
  • Versatile Applications: Given its unique design, this compound could be utilized in fields such as medicinal chemistry, materials science, and organic synthesis.
  • Analytical Challenges: The complexity of the structure may pose challenges in characterization and purification, making it an exciting topic for advanced organic chemistry students to tackle.
  • Interdisciplinary Learning: Studying compounds like this one often requires knowledge of various domains, including biochemistry, pharmacology, and material science, promoting an interdisciplinary approach to science.

Overall, this compound exemplifies the beauty of chemistry where intricate designs can lead to profound scientific discoveries and innovations. As one explores the possibilities, it is essential to remember the quote: "Chemistry is not just a science; it is a journey into the unknown."

Synonyms
642-15-9
Animicin A
antimycin A1
3-(3-Formamidosalicylamido)-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl isovalerate
EINECS 211-380-4
UNII-8771CCP8LT
Antipiricullin;Fintrol;Virosin
Antimycin A pound>>Animicin A
8771CCP8LT
SCHEMBL3717357
DTXSID20859633
HMS3866M03
BCP21022
BCP27736
NSC 723904
Butanoic acid, 2(or 3)-methyl-, (2R,3S,6S,7R,8R)-3-((3-(formylamino)-2-hydroxybenzoyl)amino)-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl ester
Butanoic acid, 2(or 3)-methyl-, 3-((3-(formylamino)-2-hydroxybenzoyl)amino)-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl ester, (2R-(2R*,3S*,6S*,7R*,8R*))-
Isovaleric acid, 8-ester with 3-formamido-N-(7-hexyl-8-hydroxy-4,9-dimethyl-2,6-dioxo-1,5-dioxonan-3-yl)salicylamide
DB-054627
NS00011650
A834677
Q418539
[3-[(3-formamido-2-oxidanyl-phenyl)carbonylamino]-8-hexyl-2,6-dimethyl-4,9-bis(oxidanylidene)-1,5-dioxonan-7-yl] 3-methylbutanoate
3-(3-formamido-2-hydroxybenzamido)-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl 3-methylbutanoate
3-methylbutanoic acid [3-[[(3-formamido-2-hydroxyphenyl)-oxomethyl]amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] ester