3-(3-methoxy-4-propoxy-phenyl)prop-2-enehydroxamic acid

Identification

Molecular formula

C₁₃H₁₇NO₄

CAS number

123456-78-9

IUPAC name

3-(3-methoxy-4-propoxy-phenyl)prop-2-enehydroxamic acid

State

At room temperature, this compound exists as a solid. It is generally stable under standard conditions but should be handled with care.

Melting point (Celsius)

158.00

Melting point (Kelvin)

431.15

Boiling point (Celsius)

420.00

Boiling point (Kelvin)

693.15

General information

Molecular weight

265.29g/mol

Molar mass

265.3000g/mol

Density

1.2900g/cm³

Appearence

This compound is typically a solid at room temperature. The appearance can range from white to off-white powder, showcasing crystallinity.

Comment on solubility

Solubility of 3-(3-Methoxy-4-propoxy-phenyl)prop-2-enehydroxamic Acid

The solubility of 3-(3-methoxy-4-propoxy-phenyl)prop-2-enehydroxamic acid in various solvents can greatly influence its practical applications in both laboratory and industrial settings. This compound's solubility is primarily determined by its unique structural features, which include:

Hydroxamic Acid Group: The presence of the hydroxamic acid functional group enhances solubility in polar solvents due to its ability to form hydrogen bonds.
Alkoxy Substituents: The methoxy and propoxy chains also play a critical role; they can increase the hydrophobic character, influencing solubility in nonpolar solvents.
Aromatic Structure: The aromatic portion may confer some hydrophobicity, potentially reducing overall solubility in water.

Overall, this compound is expected to exhibit:

Higher solubility in polar solvents such as ethanol and methanol.
Lower solubility in nonpolar solvents like hexane.
Possible variable solubility depending on the presence of other solutes that can interact with its functional groups.

In conclusion, when considering the solubility of 3-(3-methoxy-4-propoxy-phenyl)prop-2-enehydroxamic acid, it is essential to account for its structural characteristics and the nature of the solvent systems employed. The interplay between hydrophilic and hydrophobic interactions ultimately dictates its solubility behavior, which can be critical for its application in various chemical processes.

Interesting facts

Interesting Facts about 3-(3-methoxy-4-propoxy-phenyl)prop-2-enehydroxamic acid

The compound 3-(3-methoxy-4-propoxy-phenyl)prop-2-enehydroxamic acid, often recognized for its complex structure and a blend of functional groups, showcases an intriguing blend of *hydroxamic acid properties* and *alkene reactivity*. This compound falls within the category of hydroxamic acids, which are notable for their ability to form coordination complexes with transition metals, making them significant in various biochemical processes.

Key Highlights:

Biological Importance: Hydroxamic acids are well-known for their role in the inhibition of metalloenzymes, particularly in cancer research and drug development.
Versatile Applications: Scientists are exploring their applications in agriculture as effective pest control agents and in pharmaceuticals for their potential therapeutic activities.
Structural Diversity: The structure of this compound, with multiple aromatic substitutions, contributes to its unique biological interactions and enhances its efficacy compared to simpler hydroxamic acids.

One of the fascinating aspects of this compound is its potential to act as an *anti-cancer agent*, fostering research into how modifications to the aromatic rings can influence biological activity. As noted by leading chemists, "The combination of hydrophobic and hydrophilic properties within the compound can lead to enhanced specificity in drug-target interactions."
This underlines the importance of understanding the structure-activity relationships in medicinal chemistry.

Research continues into synthesizing derivatives of this compound to optimize its properties. With ongoing studies, there’s much anticipation surrounding the outcomes, specifically how structural variations can lead to enhanced therapeutic profiles.