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3-(3-methoxyphenyl)-1-[2-(4-nitrophenyl)ethyl]-3-propyl-azetidine

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Identification
Molecular formula
C21H26N2O3
CAS number
Unavailable
IUPAC name
3-(3-methoxyphenyl)-1-[2-(4-nitrophenyl)ethyl]-3-propyl-azetidine
State
State

At room temperature, this compound is typically in a solid state. Due to its crystalline nature, it can be used in powdered form, which enhances solubility in organic solvents for chemical reactions and analysis.

Melting point (Celsius)
182.00
Melting point (Kelvin)
455.15
Boiling point (Celsius)
523.00
Boiling point (Kelvin)
796.15
General information
Molecular weight
358.44g/mol
Molar mass
358.4400g/mol
Density
1.2333g/cm3
Appearence

The compound 3-(3-methoxyphenyl)-1-[2-(4-nitrophenyl)ethyl]-3-propyl-azetidine appears as an off-white to light yellow crystalline solid. It has a slightly granular texture and may also appear as a powder depending on the method of synthesis. The color can vary slightly based on purity and crystal size.

Comment on solubility

Solubility of 3-(3-methoxyphenyl)-1-[2-(4-nitrophenyl)ethyl]-3-propyl-azetidine

The solubility of 3-(3-methoxyphenyl)-1-[2-(4-nitrophenyl)ethyl]-3-propyl-azetidine can be influenced by various factors due to its complex structure. This compound, with its multiple aromatic and aliphatic components, tends to exhibit unique solubility characteristics:

  • Polarity: The presence of hydroxyl and nitro groups may introduce polarity to certain regions of the molecule, which can enhance solubility in polar solvents.
  • Hydrophobic regions: Conversely, the propyl chain and aromatic rings contribute to hydrophobic characteristics, potentially limiting solubility in water.
  • Solvent interactions: It is likely that this compound shows improved solubility in organic solvents such as ethanol, acetone, or dimethyl sulfoxide (DMSO).

Generally, it is essential to consider the following when assessing solubility:

  1. **Solvent type:** Polar versus non-polar solvents can significantly affect the solubility levels.
  2. **Temperature:** Increased temperature may lead to enhanced solubility in some solvents.
  3. **Concentration:** Higher concentrations of the compound may lead to precipitation in less compatible solvents.

In conclusion, while this compound may show moderate solubility in polar solvents, it can be substantially less soluble in water due to its hydrophobic characteristics. Therefore, careful choice of solvent and condition optimization are vital for practical applications.

Interesting facts

Interesting Facts about 3-(3-Methoxyphenyl)-1-[2-(4-nitrophenyl)ethyl]-3-propyl-azetidine

This unique compound, belonging to the azetidine family, displays intriguing properties and a wide range of potential applications. Here are some notable aspects to consider:

  • Structural Diversity: The presence of a methoxyphenyl group and a nitrophenyl group in its structure contributes to its molecular complexity, offering opportunities for investigation in medicinal chemistry.
  • Pharmacological Potential: Compounds like this one have garnered attention in drug design, particularly for their potential use in targeting various biological pathways. The incorporation of both methoxy and nitro groups may enhance the compound's pharmacophoric profile.
  • Synthetic Strategies: The synthesis of such azetidine derivatives may involve innovative synthetic routes, often utilizing techniques like multi-step synthesis or coupling reactions that could challenge budding chemists.
  • Applications in Research: As a scaffold in drug discovery, this compound could serve as a lead compound in the development of therapeutics, especially in managing conditions that require modulation of neurotransmitter activity.

Overall, 3-(3-methoxyphenyl)-1-[2-(4-nitrophenyl)ethyl]-3-propyl-azetidine represents a fascinating intersection of organic synthesis and pharmacology, making it a compound that invites further exploration and research.

Synonyms
19832-42-9
AZETIDINE, 3-(m-METHOXYPHENYL)-1-(p-NITROPHENETHYL)-3-PROPYL-
3-(m-Methoxyphenyl)-1-(p-nitrophenethyl)-3-propylazetidine
DTXSID60173567
DTXCID1096058
RefChem:320348
3-(3-methoxyphenyl)-1-[2-(4-nitrophenyl)ethyl]-3-propylazetidine