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Azetidine derivative

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Identification
Molecular formula
C20H29NO
CAS number
: "2172379-08-3
IUPAC name
3-(3-methoxyphenyl)-1-(2-phenylethyl)-3-propyl-azetidine
State
State

At room temperature, the compound remains in a solid state with a crystalline structure.

Melting point (Celsius)
98.00
Melting point (Kelvin)
371.15
Boiling point (Celsius)
357.00
Boiling point (Kelvin)
630.15
General information
Molecular weight
311.44g/mol
Molar mass
311.4430g/mol
Density
1.0235g/cm3
Appearence

The compound appears as a crystalline solid. It may be colorless to light yellow, depending on purity and other environmental factors.

Comment on solubility

Solubility of 3-(3-methoxyphenyl)-1-(2-phenylethyl)-3-propyl-azetidine

The solubility of the compound 3-(3-methoxyphenyl)-1-(2-phenylethyl)-3-propyl-azetidine can be quite intricate owing to its organic structure and the presence of various functional groups. Here are some key points to consider:

  • Polarity: The compound features both non-polar and polar elements due to the presence of aromatic rings and methoxy groups, influencing solubility in different solvents.
  • Solvent Interaction: It is generally more soluble in non-polar solvents such as hexane or chloroform than in polar solvents like water due to hydrophobic characteristics from the phenyl and propyl groups.
  • Temperature Dependence: Solubility can be temperature-dependent, with increased temperatures typically enhancing solubility, especially in organic solvents.
  • Potential for Complex Formation: In certain cases, this compound may form complexes with some solvents, further affecting solubility outcomes.

In summary, this compound exhibits selective solubility, favoring non-polar environments while exhibiting limited solubility in polar solvents. Understanding the solubility profile is crucial for applications and formulations involving this compound.

Interesting facts

Interesting Facts about 3-(3-methoxyphenyl)-1-(2-phenylethyl)-3-propyl-azetidine

This compound belongs to a fascinating class of molecules known as azetidines, which are four-membered heterocyclic rings containing a nitrogen atom. Here are some intriguing aspects of it:

  • Chemical Diversity: Azetidines showcase a variety of chemical properties owing to the presence of substituents on the ring structure. In this specific compound, the combination of a methoxyphenyl group and a phenylethyl chain exemplifies how molecular modifications can influence biological activity.
  • Pharmacological Potential: Molecules similar to this one are often studied for their potential pharmacological effects, including their role in drug design as they can interact with numerous biological targets.
  • Synthetic Route: The synthesis of these types of compounds often involves innovative organic chemistry techniques, making them fascinating subjects for research in synthetic methods.
  • Structure-Activity Relationship: Researchers frequently investigate how variations in the structure of azetidines, such as changing substituents, can alter their biological functions, leading to a better understanding of how such compounds may serve in medicinal chemistry.

As renowned chemist Linus Pauling once stated, "The best way to have a good idea is to have lots of ideas." The study of azetidines embodies this philosophy, as their unique structures and potential applications inspire a diverse array of research ideas in chemical sciences.

Beyond their chemical significance, compounds like 3-(3-methoxyphenyl)-1-(2-phenylethyl)-3-propyl-azetidine highlight the interconnectedness of organic chemistry, pharmacology, and synthetic methodologies, showcasing the endless possibilities that arise from the manipulation of molecular architecture.

Synonyms
19832-38-3
AZETIDINE, 3-(m-METHOXYPHENYL)-1-PHENETHYL-3-PROPYL-
BRN 1544114
3-(m-Methoxyphenyl)-1-phenethyl-3-propylazetidine
DTXSID00173566
3-(3-methoxyphenyl)-1-(2-phenylethyl)-3-propylazetidine
DTXCID6096057