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Identification
Molecular formula
C14H21NO2
IUPAC name
3-(3-methoxyphenyl)-3-propyl-azetidine-1-carboxamide
State
State
Solid
Melting point (Celsius)
85.00
Melting point (Kelvin)
358.15
Boiling point (Celsius)
397.00
Boiling point (Kelvin)
670.15
General information
Molecular weight
249.34g/mol
Molar mass
249.3350g/mol
Density
1.0988g/cm3
Appearence

The compound is typically crystalline in nature.

Comment on solubility

Solubility of 3-(3-Methoxyphenyl)-3-propyl-azetidine-1-carboxamide

The solubility of 3-(3-methoxyphenyl)-3-propyl-azetidine-1-carboxamide can be influenced by several factors such as its molecular structure and the nature of the solvent. Here are some key points to consider:

  • Polarity: The presence of both a methoxy group and an amide functional group suggests that the compound has a balance of polar and non-polar characteristics, which may affect its solubility in various solvents.
  • Solvent Interaction: This compound could be soluble in polar solvents like methanol or ethanol but may have limited solubility in non-polar solvents due to its polar functional groups.
  • Molecular Size: The size of the molecule, influenced by the propyl chain and the azetidine ring, may also affect its dissolution behavior, potentially leading to lower solubility in highly polar solvents.

In summary, while 3-(3-methoxyphenyl)-3-propyl-azetidine-1-carboxamide displays properties suggesting some degree of solubility, its actual behavior will largely depend on the solvent characteristics and environmental conditions. It is essential to experimentally determine its solubility in specific solvents for accurate applications.

Interesting facts

Interesting Facts about 3-(3-Methoxyphenyl)-3-propyl-azetidine-1-carboxamide

3-(3-Methoxyphenyl)-3-propyl-azetidine-1-carboxamide is a fascinating compound that has attracted attention in various fields, particularly in medicinal chemistry. Here are some intriguing highlights about this compound:

  • Structure and Function: This compound contains a four-membered azetidine ring, which contributes to its unique properties and reactivity. The addition of the propyl group enhances its hydrophobic characteristics, potentially influencing its interaction with biological systems.
  • Medicinal Potential: Due to its structural complexity, this compound could serve as a lead structure for the development of new pharmaceuticals. Analogues of azetidine derivatives are known to exhibit a range of biological activities—making this a promising area of study.
  • Substituent Significance: The presence of the methoxyphenyl group may provide enhanced binding affinity to specific biological targets, increasing the compound's efficacy in therapeutic applications. Substituents like these are often critical in drug design for optimizing biological effects.
  • Synthesis Challenges: The synthesis of azetidine derivatives may involve intricate multi-step processes, which can be a challenge for chemists. Understanding these synthetic routes is crucial for developing efficient methods for producing this compound.
  • Research Applications: Compounds like this one are often used in research settings to better understand mechanisms of action in various biochemical pathways. They can contribute to the discovery of new treatment modalities for diseases.

In conclusion, 3-(3-Methoxyphenyl)-3-propyl-azetidine-1-carboxamide exemplifies the intersection of structure and function in medicinal chemistry, showcasing the importance of synthetic exploration and biological application. As researchers continue to unravel the capabilities of such compounds, we may unlock new avenues for therapeutic interventions.

Synonyms
19832-50-9
AZETIDINE, 1-CARBAMOYL-3-(m-METHOXYPHENYL)-3-PROPYL-
1-Carbamoyl-3-(m-methoxyphenyl)-3-propylazetidine
DTXSID80173569
DTXCID5096060
RefChem:320338
3-(3-methoxyphenyl)-3-propylazetidine-1-carboxamide