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3-(1H-Indol-3-ylmethyl)-3-methylpiperidine

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Identification
Molecular formula
C15H20N2
CAS number
78087-22-0
IUPAC name
3-[(3-methyl-1-piperidyl)methyl]-1H-indole
State
State

At room temperature, this compound is typically found in a solid state.

Melting point (Celsius)
58.70
Melting point (Kelvin)
331.90
Boiling point (Celsius)
362.70
Boiling point (Kelvin)
635.90
General information
Molecular weight
240.35g/mol
Molar mass
240.3530g/mol
Density
1.1580g/cm3
Appearence

The compound is a white to off-white crystalline solid, typically appearing as a powder. It exhibits no significant odor and is stable under standard laboratory conditions.

Comment on solubility

Solubility of 3-[(3-methyl-1-piperidyl)methyl]-1H-indole

The solubility of 3-[(3-methyl-1-piperidyl)methyl]-1H-indole is an essential aspect of its chemical behavior and applications. This compound showcases a unique combination of structural features that influence its solubility characteristics in various solvents. Here are some key points to consider:

  • Polarity: The presence of the piperidyl group suggests that the molecule may exhibit moderate polarity, enhancing its solubility in polar solvents.
  • Solvent Compatibility: It is expected to demonstrate good solubility in polar organic solvents such as ethanol and methanol.
  • Non-Polar Solvents: Conversely, the compound may have limited solubility in non-polar solvents like hexane or toluene.
  • pH Influence: The solubility might vary with changes in pH, particularly due to ionization of certain functional groups in solution.

Understanding these solubility factors is crucial for applications in drug formulation and chemical synthesis, making it essential to consider solvent interactions when working with this compound. Overall, the solubility profile of 3-[(3-methyl-1-piperidyl)methyl]-1H-indole underlines the importance of examining each unique component of a chemical structure to predict its behavior in various environments.

Interesting facts

Exploring 3-[(3-methyl-1-piperidyl)methyl]-1H-indole

The compound 3-[(3-methyl-1-piperidyl)methyl]-1H-indole holds a unique position in the field of organic chemistry, mainly due to its interesting structural characteristics and potential applications. This compound is derived from indole, a fundamental component that is pivotal in numerous biological systems.

Key Features of 3-[(3-methyl-1-piperidyl)methyl]-1H-indole

  • Biological Relevance: Indole derivatives are known for their presence in many natural products, underlining their importance in pharmaceutical development. The modification of indole with a piperidine ring can enhance biological activity.
  • Pharmaceutical Applications: This compound may exhibit potential as a pharmacophore, making it a target for the synthesis of new medicinal agents. Molecules similar to this have been explored for their roles as receptor modulators.
  • Structure-Activity Relationship (SAR): The presence of a piperidyl group can significantly influence the compound's interaction with biological targets, showcasing the importance of small structural changes in medicinal chemistry.
  • Research Interest: Chemists are continually interested in compounds like this due to their complex mechanisms of action and the diverse pathways they can influence.

In summary, 3-[(3-methyl-1-piperidyl)methyl]-1H-indole is a fascinating compound that illustrates the intricate relationship between structure and function in organic chemistry. As research advances, this compound may unlock new therapeutic avenues and enhance our understanding of indole chemistry.

Synonyms
19213-30-0
BRN 0193157
3-((3-Methylpiperidino)methyl)indole
INDOLE, 3-((3-METHYLPIPERIDINO)METHYL)-
4-22-00-04307 (Beilstein Handbook Reference)
RefChem:349182
3-[(3-methylpiperidin-1-yl)methyl]-1H-indole
3-((3-Methylpiperidin-1-yl)methyl)-1H-indole
DTXSID30940864
AKOS024323323
3-[(3-methyl-1-piperidinyl)methyl]-1H-indole