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3-(3-methyl-4-propoxy-phenyl)prop-2-enehydroxamic acid

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Identification
Molecular formula
C13H17NO3
CAS number
89678-77-1
IUPAC name
3-(3-methyl-4-propoxy-phenyl)prop-2-enehydroxamic acid
State
State
This compound is typically found in a solid state at room temperature. It is often in the form of a crystalline powder.
Melting point (Celsius)
137.80
Melting point (Kelvin)
410.95
Boiling point (Celsius)
381.50
Boiling point (Kelvin)
654.65
General information
Molecular weight
235.30g/mol
Molar mass
235.2950g/mol
Density
1.0450g/cm3
Appearence

The compound is generally found as a solid, crystalline powder. It appears as a white or off-white substance.

Comment on solubility

Solubility of 3-(3-methyl-4-propoxy-phenyl)prop-2-enehydroxamic acid

The solubility of 3-(3-methyl-4-propoxy-phenyl)prop-2-enehydroxamic acid can be influenced by several factors:

  • Polarity: This compound contains both non-polar and polar functional groups, which can affect its solubility in various solvents.
  • Hydrogen bonding: The presence of a hydroxamic acid functional group can enhance solubility in polar solvents like water due to its ability to form hydrogen bonds.
  • Chain Length and Branching: The propoxy side chain increases hydrophobic characteristics, which may decrease solubility in highly polar solvents.
  • pH Influence: The solubility might vary with pH levels, as acidic or basic conditions can influence the ionization of the hydroxamic group, thereby altering its solubility profile.

In general, it is essential to assess solubility through experimental methods, as theoretical predictions can vary significantly based on the specific conditions.

In summary, the solubility of 3-(3-methyl-4-propoxy-phenyl)prop-2-enehydroxamic acid is complex and must be evaluated considering:

  1. Solvent type
  2. Temperature
  3. Concentration

Understanding these variables will provide a comprehensive view of how this compound behaves in solution.

Interesting facts

Interesting Facts about 3-(3-methyl-4-propoxy-phenyl)prop-2-enehydroxamic acid

3-(3-methyl-4-propoxy-phenyl)prop-2-enehydroxamic acid is an intriguing compound that belongs to the class of hydroxamic acids, which are recognized for their versatile applications in various fields of chemistry. Here are some fascinating insights about this compound:

  • Hydroxamic Acid Significance: Hydroxamic acids are known for their unique functionality, featuring the –C(=O)N(OH)R group, which allows them to act as efficient chelating agents for metal ions, making them important in the field of coordinate chemistry.
  • Potential Biological Activities: Compounds in the hydroxamic acid family are often studied for their biological activities, including antibacterial, antifungal, and anticancer properties. They can inhibit specific enzymes, such as metalloproteinases, which are involved in tissue remodeling and cancer metastasis.
  • Versatile Applications: Due to their chelation properties, hydroxamic acids find applications beyond pharmaceuticals. They are also utilized in agriculture for the formulation of herbicides and plant growth regulators, showcasing their ability to interact with essential metal ions in biological systems.
  • Structure-Activity Relationship (SAR): The intricate structure of 3-(3-methyl-4-propoxy-phenyl)prop-2-enehydroxamic acid presents researchers with a valuable system to study the relationship between molecular structure and biological activity. Modifications to the propoxy and methyl groups can lead to differing activity profiles, contributing to ongoing research and development.
  • Research Opportunities: The combination of the phenyl ring with hydroxamic acid provides ample research opportunities for synthetic chemists, particularly in the development of new compounds with enhanced properties. This compound can serve as a lead for designing new drugs with improved efficacy and reduced side effects.

In conclusion, 3-(3-methyl-4-propoxy-phenyl)prop-2-enehydroxamic acid stands as a remarkable example of how small modifications in chemical structure can lead to diverse applications in science. It is a prime candidate for further study, both in laboratory settings and potential industrial applications.