Dracorhodin | Solubility of Things

Identification

Molecular formula

C₁₆H₁₀N₂O₃

CAS number

10488-10-3

IUPAC name

3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol

State

The compound is in a solid state at room temperature.

Melting point (Celsius)

190.00

Melting point (Kelvin)

463.15

Boiling point (Celsius)

550.00

Boiling point (Kelvin)

823.15

General information

Molecular weight

316.26g/mol

Molar mass

316.2800g/mol

Density

1.4500g/cm³

Appearence

The compound typically appears as a crystalline solid. Its color may vary depending on purity and form, but it is generally colored due to the presence of the indole structure which is known for its vibrant hues in many compounds.

Comment on solubility

Solubility of 3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol

The solubility of 3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol (C₁₆H₁₀N₂O₃) can be characterized by various factors that influence its interaction with solvents. This compound contains both indole and nitroso groups, which can significantly affect its solubility profile.

Polarity: The presence of the nitroso group may increase polarity, suggesting a potential for solubility in polar solvents like water.
Hydrophobic Nature: However, the indole structure is known to exhibit hydrophobic characteristics, which could limit its solubility in aqueous environments.
Solvent Compatibility: This compound likely shows better solubility in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), or acetone due to the hydrophobic interactions from the indole rings.

Experiments indicate that solubility can also depend on factors such as temperature and pH. For instance:

At elevated temperatures, solubility in some solvents may increase.
Varying the pH can also influence the ionization state of the compound, thereby affecting its solubility.

In summary, while 3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol may exhibit some solubility in polar solvents, its overall solubility is likely constrained by its hydrophobic indole components. Researchers should consider these factors when working with this compound in solution.

Interesting facts

Interesting Facts About 3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol

3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol, often referred to as a nitroso derivative of indole, is a fascinating compound with a variety of intriguing properties and potential applications.

Key Points of Interest:

Indole Structure: Indole is a well-known aromatic compound that plays a critical role in many biological processes. The presence of the nitroso group in this compound introduces interesting reactivity due to the potential for electrophilic reactions.
Biological Activity: Compounds containing indole moieties are frequently investigated for their pharmacological properties. This specific derivative is of particular interest in research focused on anti-cancer and neuroprotective effects.
Versatile Building Block: The indole structure is utilized extensively in the synthesis of various pharmaceuticals, including antidepressants and anticancer agents. The incorporation of the nitroso group can enhance these compounds' properties and increase their effectiveness.
Potential for Innovation: Researchers are exploring nitroso compounds like this one for novel applications in materials science, organic electronics, and as intermediates in organic synthesis.

In summary, 3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol demonstrates the complex interplay between structure and function in chemical compounds. As scientists continue to study this compound, we can expect to unveil more about its utility and importance in both biological systems and synthetic applications.

Synonyms

INDIRUBIN-3'-MONOXIME

indirubin-3'-oxime

160807-49-8

Indirubin-3-monoxime

667463-82-3

indirubin-3-oxime

Indirubin-3monoxime

Indirubin 3'-monoxime

Indirubin 3-oxime

CHEBI:43645

3-[3-(Hydroxyamino)-1H-indol-2-yl]indol-2-one

Indirubin-3a?oxime

indirubin-3'-monooxime

Indirubin-3 inverted exclamation marka-oxime

(2Z,3E)-3-(Hydroxyimino)-[2,3'-biindolinylidene]-2'-one

MFCD02683594

X6CSG51MBQ

2H-Indol-2-one, 3-[1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-

CHEMBL126077

CHEMBL216543

CHEMBL1496098

(Z)-1H,1'H-[2,3']BIINDOLYLIDENE-3,2'-DIONE-3-OXIME

DTXSID90416111

1H,1'H-[2,3']biindolylidene3,2'-dione-3-oxime

3-(Hydroxyimino)-[2,3'-biindolinylidene]-2'-one

3-[1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one

UNM-0000305771

3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol

3-[3-(hydroxyamino)-1H-indol-2-yl]-2H-indol-2-one

(3Z)-3-[(3E)-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one

IXM

indirubin 3'-oxime

SR-01000075929

1H,1'H-(2,3')biindolylidene3,2'-dione-3-oxime

3-(3-(hydroxyamino)-1H-indol-2-yl)-2H-indol-2-one

3-(HYDROXYIMINO)-(2,3'-BIINDOLINYLIDENE)-2'-ONE

Indirubin-3

(Z,3E)-3-(hydroxyimino)-1',2'-dihydro-1H,3H-(2,3'-biindolyliden)-2'-one

(Z,3E)-3-(hydroxyimino)-1',2'-dihydro-1H,3H-[2,3'-biindolyliden]-2'-one

2H-INDOL-2-ONE, 3-(1,3-DIHYDRO-3-(HYDROXYIMINO)-2H-INDOL-2-YLIDENE)-1,3-DIHYDRO-

3-(1,3-DIHYDRO-3-(HYDROXYIMINO)-2H-INDOL-2-YLIDENE)-1,3-DIHYDRO-2H-INDOL-2-ONE

(3Z)-3-((3E)-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one

Indirubin-3'-oxime; 3-[1,3-Dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one;

Indirubin-3??-oxime

Tocris-1813

Indirubin-3'-monoxime?

BiomolKI_000070

UNII-X6CSG51MBQ

Lopac-I-0404

BiomolKI2_000074

Lopac0_000619

BSPBio_001108

KBioGR_000448

KBioSS_000448

SCHEMBL378779

BMK1-G10

GTPL5989

SCHEMBL1574499

SCHEMBL12005849

SCHEMBL13046776

SCHEMBL13714093

BCBcMAP01_000150

BDBM54681

CHEBI:92352

cid_5326739

KBio2_000448

KBio2_003016

KBio2_005584

KBio3_000835

KBio3_000836

DTXCID90366960

1q41

HBDSHCUSXQATPO-BGBJRWHRSA-N

Bio2_000394

Bio2_000874

GLXC-02351

HMS1362H09

HMS1792H09

HMS1990H09

HMS3229C06

HMS3260M14

HMS3268I10

HMS3403H09

HMS3412J10

HMS3676J10

ML015

BCP14390

Tox21_500146

BDBM50132003

BDBM50166289

BDBM50580887

HSCI1_000200

NSC717829

s2009

AKOS015910263

AKOS024456796

AKOS030241899

AKOS037647459

AKOS040759689

CCG-100674

CS-5425

DB02052

FI24572

Indirubin-3-monoxime;Indirubin-3-oxime

LP00146

NSC-717829

SDCCGSBI-0050601.P003

SDCCGSBI-0050601.P007

IDI1_002149

NCGC00015545-01

NCGC00015545-02

NCGC00015545-03

NCGC00015545-04

NCGC00015545-05

NCGC00015545-06

NCGC00015545-07

NCGC00015545-08

NCGC00015545-11

NCGC00025304-01

NCGC00025304-02

NCGC00025304-03

NCGC00025304-04

NCGC00025304-05

NCGC00260831-01

AC-30025

AS-73725

BS-51837

DA-54307

DA-74477

HY-19807

NCI60_040633

HY-139254

CS-0182654

EU-0100619

NS00073176

Indirubin-3'-oxime, >=98% (HPLC), solid

I 0404

K00076

Indirubin-3'-monoxime - CAS 160807-49-8

3-[3-(hydroxyamino)-1H-indol-2-yl]-2-indolone

3-[3-(oxidanylamino)-1H-indol-2-yl]indol-2-one

3-(3-(hydroxyimino)indolin-2-ylidene)indolin-2-one

SR-01000075929-1

SR-01000075929-3

BRD-K19136521-001-01-4

BRD-K19136521-001-08-9

BRD-K53959060-001-01-3

Q27078054

Q27461594

1H,1''H-[2,3'']Biindolylidene-3,2''-dione 3-oxime

(2Z,3E)-2,3'-biindole-2',3(1H,1'H)-dione 3-oxime

(2E,3E)-3-(hydroxyimino)-[2,3'-biindolinylidene]-2'-one

(2Z,3Z)-3-(hydroxyimino)-[2,3'-biindolinylidene]-2'-one

(3Z)-3-[(3E)-3-hydroxyiminoindolin-2-ylidene]indolin-2-one

(Z)-1H,1''H-[2,3'']Biindolylidene-3,2''-dione 3-oxime

1H,1''''H-[2,3'''']Biindolylidene-3,2''''-dione 3-oxime

(Z)-1H,1''''H-[2,3'''']Biindolylidene-3,2''''-dione 3-oxime

3-(hydroxyimino)-1',2'-dihydro-1H,3H-[2,3'-biindolyliden]-2'-one

2H-Indol-2-one,3-[1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-

2H-Indol-2-one, 3-[1,3-dihydro-3-(hydroxyamino)-2H-indol-2-ylidene]-1,3-dihydro-, (3Z)-

Indirubin-3'-oxime;3-[1,3-Dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one