Skip to main content

3-(3-pyridylmethyl)-1H-indole

ADVERTISEMENT
Identification
Molecular formula
C14H12N2
CAS number
1133-33-3
IUPAC name
3-(3-pyridylmethyl)-1H-indole
State
State

At room temperature, 3-(3-pyridylmethyl)-1H-indole is in a solid state. It is typically handled and stored as a crystalline powder.

Melting point (Celsius)
123.00
Melting point (Kelvin)
396.15
Boiling point (Celsius)
409.30
Boiling point (Kelvin)
682.50
General information
Molecular weight
220.28g/mol
Molar mass
220.2820g/mol
Density
1.2140g/cm3
Appearence

This compound appears as a solid, typically in a crystalline powder form. The color can vary depending on the specific sample's purity and storage conditions, but it is generally described as a white or off-white solid.

Comment on solubility

Solubility of 3-(3-pyridylmethyl)-1H-indole

3-(3-pyridylmethyl)-1H-indole is a compound of notable interest due to its unique structure, which influences its solubility characteristics. Understanding the solubility of such organic compounds is crucial, as it plays a significant role in their application and behavior in various environments.

Generally, solubility can be categorized based on the following factors:

  • Polarity of the Compound: 3-(3-pyridylmethyl)-1H-indole contains both aromatic and heterocyclic components, which contribute to its polarity. This can lead to varied solubility in polar and non-polar solvents.
  • Hydrogen Bonding: The presence of nitrogen in the pyridine ring may allow for hydrogen bonding with suitable solvents, enhancing its solubility in polar solvents such as water.
  • Temperature: Like many organic compounds, the solubility of 3-(3-pyridylmethyl)-1H-indole can increase with temperature. Therefore, solubility studies should be conducted at different temperatures to determine its full potential.

In summary, while the solubility of 3-(3-pyridylmethyl)-1H-indole can be considered moderate, its unique properties require careful examination. As noted by solubility experts, "Understanding a compound's solubility profile is vital for predicting its behavior in chemical reactions and biological systems." Consequently, further research into the solubility of this compound in various solvents will provide invaluable insights into its practical applications.

Interesting facts

Interesting Facts about 3-(3-Pyridylmethyl)-1H-Indole

3-(3-Pyridylmethyl)-1H-indole is a fascinating compound that serves as a cornerstone for various scientific explorations. Its unique structure, derived from the indole framework combined with a pyridine moiety, lends it an array of intriguing properties and potential applications. Here are some captivating aspects of this compound:

  • Diverse Biological Activities: This compound has garnered attention in medicinal chemistry for its potential pharmacological effects, including anti-cancer and anti-inflammatory properties. Its structural similarity to naturally occurring compounds enables it to interact with biological systems effectively.
  • Role in Research: 3-(3-Pyridylmethyl)-1H-indole is often utilized as a research tool in studying biological pathways. Its ability to serve as a ligand for various receptors makes it an essential candidate in drug discovery programs.
  • Synthesis Challenges: The synthesis of this compound can present challenges due to its complex structure. Chemists need to employ advanced techniques such as multi-step synthesis and careful reaction conditions to obtain it in pure form.
  • Analytical Techniques: Characterization of 3-(3-pyridylmethyl)-1H-indole typically involves a blend of spectroscopy methods like NMR, mass spectrometry, and infrared spectroscopy. These techniques allow scientists to confirm its structure and purity effectively.
  • Potential in Material Science: Beyond its biological applications, this compound may also find utility in material science. Its distinct properties could lead to innovations in organic electronics and photonic devices.

In conclusion, 3-(3-pyridylmethyl)-1H-indole stands out not only for its structural elegance but also for its vast potential in both medicinal and material research. As scientists continue to unravel the complexities of this compound, we may uncover even more applications that could impact various fields.

Synonyms
5275-04-7
ICIG 879
beta-(3'-Indolyl)methylpyridine
1H-INDOLE, 3-(3-PYRIDINYLMETHYL)-
3-(3-Pyridinylmethyl)-1H-indole
BRN 0745202
DTXSID30200733
DTXCID60123224
5-23-08-00523 (beilstein handbook reference)
3-(pyridin-3-ylmethyl)-1H-indole
3-Pyridin-3-ylmethyl-1H-indole
3-(3-pyridylmethyl)indole
3-[(pyridin-3-yl)methyl]-1H-indole
SCHEMBL5870915
ORBYFAFBEOHNKJ-UHFFFAOYSA-N
AKOS015941286
DB-294478