Skip to main content

Modafinil

ADVERTISEMENT
Identification
Molecular formula
C15H15NO2S
CAS number
68693-11-8
IUPAC name
3-(3,3-dimethyl-1-phenyl-2-benzothiophen-1-yl)-N-methyl-propan-1-amine
State
State
At room temperature, Modafinil is in a solid-state, specifically as a crystalline powder.
Melting point (Celsius)
164.00
Melting point (Kelvin)
437.20
Boiling point (Celsius)
382.50
Boiling point (Kelvin)
655.70
General information
Molecular weight
273.37g/mol
Molar mass
273.3750g/mol
Density
1.3000g/cm3
Appearence

Modafinil is a white to off-white crystalline powder that is practically insoluble in water and cyclohexane. It is slightly soluble in methanol and acetone.

Comment on solubility

Solubility of 3-(3,3-dimethyl-1-phenyl-2-benzothiophen-1-yl)-N-methyl-propan-1-amine

The solubility of the compound 3-(3,3-dimethyl-1-phenyl-2-benzothiophen-1-yl)-N-methyl-propan-1-amine in various solvents can be quite nuanced. This compound exhibits specific solubility characteristics based on its chemical structure, which includes a bulky phenyl group and a benzothiophene moiety. Here are some important points to note:

  • Polar Solvents: The presence of the amine functional group might suggest some degree of solubility in polar solvents, especially in water and alcohols. However, due to the hydrophobic nature of the phenyl and benzothiophene parts, solubility is likely to be limited.
  • Non-Polar Solvents: It is more probable that this compound will show higher solubility in non-polar solvents such as hexane or chloroform, owing to its large hydrophobic regions. The overall structural bulk can significantly enhance compatibility with non-polar environments.
  • Temperature Dependency: Solubility can also vary with temperature changes. Generally, an increase in temperature can enhance the solubility of solid compounds.

For practical applications, it is crucial to conduct solubility tests to identify the best solvent for dissolution. As chemists often say, "Like dissolves like", meaning that the compound may dissolve better in a solvent that has similar polarity. Understanding the solubility characteristics can aid in the selection of appropriate solvents for processes such as extraction, formulation, or synthesis.

Interesting facts

Interesting Facts About 3-(3,3-dimethyl-1-phenyl-2-benzothiophen-1-yl)-N-methyl-propan-1-amine

This compound, often referred to in the scientific community as a potential **designer drug**, showcases intriguing properties that have garnered attention in both academic and practical fields. Below are some noteworthy aspects:

  • Chemical Structure: The unique arrangement of the benzothiophene and alkyl groups in the compound suggests interesting interactions with biological systems. The presence of the phenyl group contributes to its unique reactivity and stability.
  • Pharmaceutical Potential: Compounds similar to this structure are often investigated for their pharmacological properties. There is ongoing research into how modifications on the amine group may alter the compound's effects, which can be valuable for medicinal chemistry.
  • Research Interest: The compound serves as a model for studying the structure-activity relationship in the field of neurochemistry. Scientists are keen to understand how small changes in the chemical structure can lead to significant changes in biological activity.
  • Toxicological Studies: Because of its structural features, the compound has spurred interest in toxicology studies. Understanding the safety profile is essential, especially given its potential use in experimental settings.

This compound is more than just a chemical formula; it represents a bridge between **synthetic chemistry** and **biological applications**. As research continues to unfold, it is likely that even more fascinating characteristics will be revealed. As one researcher aptly noted, "The beauty of organic compounds lies in their complexity and the hidden potentials they hold."

Thus, the exploration of 3-(3,3-dimethyl-1-phenyl-2-benzothiophen-1-yl)-N-methyl-propan-1-amine remains an exciting frontier in scientific inquiry.

Synonyms
Talsupram
21489-20-3
Talsupramum
C6Z73MW6CR
RefChem:932531
(3-(3,3-dimethyl-1-phenyl-1,3-dihydro-2-benzothiophen-1-yl)propyl)(methyl)amine
Talsupram [INN]
CHEMBL52247
3-(3,3-dimethyl-1-phenyl-2-benzothiophen-1-yl)-N-methylpropan-1-amine
3-(3,3-Dimethyl-1-phenyl-1,3-dihydrobenzo[c]thiophen-1-yl)-N-methylpropan-1-amine
Lu 5-005
Talsupramum [INN-Latin]
UNII-C6Z73MW6CR
SCHEMBL114515
orb2814870
DTXSID50864992
BDBM50021217
DB09191
Q7680329
1,3-Dihydro-N,3,3-trimethyl-1-phenylbenzo(c)thiophen-1-propylamin
1,3-Dihydro-N,3,3-trimethyl-1-phenylbenzo(c)thiophene-1-propylamine
Benzo(c)thiophene-1-propanamine, 1,3-dihydro-N,3,3-trimethyl-1-phenyl-
Benzo(c)thiophene-1-propylamine, 1,3-dihydro-N,3,3-trimethyl-1-phenyl-
3-(3,3-dimethyl-1-phenyl-1,3-dihydro-2-benzothiophen-1-yl)-N-methylpropan-1-amine
N-Methyl-3-(3,3-dimethyl-1-phenyl-1,3-dihydrobenzo(c)phiophen-1-yl)propylamin
[3-(3,3-Dimethyl-1-phenyl-1,3-dihydro-benzo[c]thiophen-1-yl)-propyl]-methyl-amine(Talsupram)