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Venlafaxine

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Identification
Molecular formula
C17H27NO2
CAS number
93413-69-5
IUPAC name
3-(3,3-dimethyl-1-phenyl-isobenzofuran-1-yl)-N-methyl-propan-1-amine
State
State

Venlafaxine is generally found in a solid state at room temperature.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
465.40
Boiling point (Kelvin)
738.55
General information
Molecular weight
277.40g/mol
Molar mass
277.4000g/mol
Density
1.1200g/cm3
Appearence

Venlafaxine is a white to off-white crystalline solid.

Comment on solubility

Solubility of 3-(3,3-Dimethyl-1-phenyl-isobenzofuran-1-yl)-N-methyl-propan-1-amine

The solubility of the compound 3-(3,3-dimethyl-1-phenyl-isobenzofuran-1-yl)-N-methyl-propan-1-amine is influenced by several factors, including its molecular structure and the presence of functional groups. This compound is a bit complex, and its solubility characteristics can be summarized as follows:

  • Polarity: The presence of both hydrophobic and hydrophilic sections in the molecule suggests that it may demonstrate selective solubility in organic solvents rather than in water.
  • Solvent Compatibility: It is likely to be soluble in non-polar or low-polarity solvents due to its significant hydrocarbon structure.
  • Temperature Variation: Solubility can vary with temperature, where increased thermal energy may enhance solubility in organic solvents.
  • Degree of Ionization: If the compound can form ions, pH changes in the solution may impact its solubility, particularly in aqueous media.

In general, predicting the solubility of complex organic compounds can be challenging. As such, it is essential to conduct empirical solubility tests in various solvents to determine the precise solubility characteristics of this compound. Remember, *“A compound’s solubility is not just a physical property; it reveals insights into its molecular behavior and potential applications.”*

Interesting facts

Interesting Facts about 3-(3,3-dimethyl-1-phenyl-isobenzofuran-1-yl)-N-methyl-propan-1-amine

This compound is a fascinating example of an organic molecule with a complex structure. Here are some points of interest:

  • Structure and Function: The unique combination of a phenyl group and an isobenzofuran moiety in this compound contributes to its intriguing electronic and steric properties. The presence of the amine functional group also suggests potential for biological activity, which could lead to pharmaceutical applications.
  • Synthetic Pathways: Synthesis of such compounds often involves a multi-step process, showcasing the creativity and precision required in organic chemistry. This can include various reactions like Friedel-Crafts acylation, rearrangement reactions, and amine coupling.
  • Potential Applications: Compounds like this are of interest in industries like agrochemicals, pharmaceuticals, and materials science. Their unique structures can lead to novel functional properties, making them suitable for use in drug design and synthesis.
  • Research Significance: The study of compounds with similar structures is active in medicinal chemistry due to their potential effects on biological systems. Investigating their mechanisms can lead to breakthroughs in understanding various diseases.

In summary, 3-(3,3-dimethyl-1-phenyl-isobenzofuran-1-yl)-N-methyl-propan-1-amine exemplifies the rich complexity of organic molecules, embodying significant potential both in research and application. The exploration of such compounds not only enhances our understanding of organic chemistry but also opens doors to innovative solutions in various fields.

Synonyms
TALOPRAM
Phthalapromine
Talopram [INN]
Talopramum
Talopran
Talopramum [INN-Latin]
Talopran [INN-Spanish]
(11C)talopram
N,3,3-Trimethyl-1-phenyl-1-phthalanpropylamin
UNII-5PY881HC79
5PY881HC79
1-Isobenzofuranpropanamine, 1,3-dihydro-N,3,3-trimethyl-1-phenyl-
AY 21554
Talopramum (INN-Latin)
Talopran (INN-Spanish)
1,3-Dihydro-1,1-dimethyl-3-(3-methylaminopropyl)-3-phenylisobenzofuran
N,3,3-TRIMETHYL-1-PHENYL-1-PHTHALANPROPYLAMINE
(3-(3,3-dimethyl-1-phenyl-1,3-dihydro-2-benzofuran-1-yl)propyl)(methyl)amine
[3-(3,3-dimethyl-1-phenyl-1,3-dihydro-2-benzofuran-1-yl)propyl](methyl)amine
1,3-dihydro-N,3,3-trimethyl-1-phenylbenzo(c)furan-1-propanamine
lu 3-010
7182-51-6
CHEMBL299233
3-(3,3-dimethyl-1-phenyl-2-benzofuran-1-yl)-N-methylpropan-1-amine
Lu 3-010 hydrochloride
SCHEMBL399706
DTXSID10864019
BDBM50021246
DB09190
NCGC00371094-01
WLN: T56 COT&J B3M1 BR& D1 D1 &GH
1-Phthalanpropylamine,3,3-trimethyl-, hydrochloride
Q7680301
3,3-Dimethyl-1-(3-methylaminopropyl)-1-phenylphthalene
1-Phthalanpropylamine,3,3-trimethyl-1-phenyl-, hydrochloride
Phthalan,3-dimethyl-1-(3-methylaminopropyl)-1-phenyl-, hydrochloride
[3-(3,3-Dimethyl-1-phenyl-1,3-dihydro-isobenzofuran-1-yl)-propyl]-methyl-amine(Talopram)
1-Isobenzofuranpropanamine,3-dihydro-N,3,3-trimethyl-1-phenyl-, hydrochloride
3-(3,3-dimethyl-1-phenyl-1,3-dihydroisobenzofuran-1-yl)-N-methylpropan-1-amine