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Nefazodone

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Identification
Molecular formula
C25H32ClNO2S
CAS number
82986-04-3
IUPAC name
3-(3,3-dimethyl-2,2-dioxo-1-phenyl-2-benzothiophen-1-yl)-N-methyl-propan-1-amine
State
State

At room temperature, Nefazodone is a solid.

Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
475.30
Boiling point (Kelvin)
748.45
General information
Molecular weight
469.61g/mol
Molar mass
469.6080g/mol
Density
1.3500g/cm3
Appearence

Nefazodone appears as a white to off-white crystalline powder. It is odorless and has a bitter taste.

Comment on solubility

Solubility of 3-(3,3-dimethyl-2,2-dioxo-1-phenyl-2-benzothiophen-1-yl)-N-methyl-propan-1-amine

The solubility of 3-(3,3-dimethyl-2,2-dioxo-1-phenyl-2-benzothiophen-1-yl)-N-methyl-propan-1-amine in various solvents is a critical factor to consider in its applications. This compound exhibits a complex structure, which influences its solubility properties. Below are key insights regarding its solubility:

  • Polar Solvents: Typically, compounds containing functional groups similar to this one may show **limited solubility** in polar solvents such as water due to their hydrophobic nature.
  • Non-Polar Solvents: On the other hand, it may be more soluble in non-polar solvents like hexane or chloroform, where the interactions are favorable.
  • Temperature Effects: Solubility can also be **temperature-dependent**; increasing temperature often enhances solubility for solid compounds.
  • pH Influence: Changes in pH can affect the solubility of this amine compound, especially if protonation or deprotonation occurs, altering its solubility behavior.

In summary, understanding the solubility behavior of 3-(3,3-dimethyl-2,2-dioxo-1-phenyl-2-benzothiophen-1-yl)-N-methyl-propan-1-amine is essential for effectively utilizing this compound in various chemical environments. As always, experimentation and empirical data are crucial to draw definitive conclusions about solubility in practical applications.

Interesting facts

Interesting Facts about 3-(3,3-dimethyl-2,2-dioxo-1-phenyl-2-benzothiophen-1-yl)-N-methyl-propan-1-amine

This compound is an intriguing member of the group of benzothiophene derivatives, showcasing a rich landscape of chemical properties and potential applications. Here are some key insights:

  • Structural Complexity: The compound features a complex structure with multiple functional groups, which can affect its reactivity and interactions with other molecules.
  • Pharmacological Interest: Compounds similar to this one have gained attention for their potential use in medicinal chemistry, particularly in designing new drugs for various diseases.
  • Benzothiophene Influence: The presence of the benzothiophene ring is known for impacting biological activities, making it a focal point for studies in organic and pharmaceutical chemistry.
  • Dioxo Groups: The dioxo groups present in the structure contribute to the compound's ability to form hydrogen bonds, which can enhance its biological activities and interactions.
  • Potential Applications: Beyond medicinal uses, such compounds are often researched for their roles in materials science, especially in creating novel materials with unique electronic properties.

As a chemical scientist or a student, studying compounds like this can unlock new understandings of structure-activity relationships, guiding the development of innovative therapeutic agents. The intricate balance of structure and function in 3-(3,3-dimethyl-2,2-dioxo-1-phenyl-2-benzothiophen-1-yl)-N-methyl-propan-1-amine is a testament to the beauty and complexity of organic chemistry.