Amiodarone | Solubility of Things

Identification

Molecular formula

C₂₅H₂₉Cl₂INO₃

CAS number

1951-25-3

IUPAC name

3-(3,4-dichlorophenyl)-1-[6-[2-(dimethylamino)ethoxy]-4,7-dimethoxy-benzofuran-5-yl]prop-2-en-1-one

State

At room temperature, Amiodarone is a solid.

Melting point (Celsius)

157.00

Melting point (Kelvin)

430.00

Boiling point (Celsius)

537.00

Boiling point (Kelvin)

810.00

General information

Molecular weight

645.32g/mol

Molar mass

645.3200g/mol

Density

1.1100g/cm³

Appearence

Amiodarone is a white crystalline powder. It is slightly soluble in water, more soluble in methanol, and soluble in dichloromethane.

Comment on solubility

Solubility of 3-(3,4-dichlorophenyl)-1-[6-[2-(dimethylamino)ethoxy]-4,7-dimethoxy-benzofuran-5-yl]prop-2-en-1-one

The solubility of the compound 3-(3,4-dichlorophenyl)-1-[6-[2-(dimethylamino)ethoxy]-4,7-dimethoxy-benzofuran-5-yl]prop-2-en-1-one is an important factor in its application and bioavailability. Solubility can greatly influence the efficacy of a substance, as it determines how well the compound can interact with biological systems.

Key points to consider regarding its solubility include:

Solvent Properties: The compound's solubility may vary significantly in different solvents. Typically, a comparison between polar and non-polar solvents will yield insight into its solubility characteristics.
pH Influence: The solubility often depends on the pH of the solution, which can alter the ionization state of the compound. Monitoring these changes can provide valuable information about its solubility behavior.
Temperature Dependency: With increasing temperature, solubility can increase, though this relationship can vary based on the compound's specific interactions at different thermal conditions.
Structural Factors: The presence of functional groups, such as dimethylamino and methoxy groups, can enhance solubility due to their ability to engage in hydrogen bonding or dipole interactions.

In conclusion, understanding the solubility of this compound is crucial for its applications in pharmaceuticals and other fields. Comprehensive studies, including the assessment of solubility in various media and under differing conditions, are essential for maximizing the compound's efficiency and therapeutic potential.

Interesting facts

Interesting Facts About 3-(3,4-Dichlorophenyl)-1-[6-[2-(dimethylamino)ethoxy]-4,7-dimethoxy-benzofuran-5-yl]prop-2-en-1-one

This compound represents a fascinating intersection of medicinal and environmental chemistry. It belongs to a class of organic compounds known for their diverse pharmacological effects. Here are some intriguing aspects of this compound:

Structural Complexity: The molecule features a unique combination of a benzofuran moiety, which is significant due to its occurrence in numerous natural products and therapeutic agents.
Chlorophenyl Group: The presence of the dichlorophenyl group is noteworthy. Chlorinated aromatic compounds often exhibit enhanced biological activity, making them prevalent in agrochemicals and pharmaceuticals.
Dimethylamino Ethoxy Side Chain: The dimethylamino group contributes to the compound's potential as a biochemical probe or therapeutic agent, improving solubility and biological interactions.
Pharmacological Potential: This compound's intricate structure suggests it may interact with various biological pathways, potentially leading to the development of new drugs targeting areas like oncology or neuropharmacology.
Environmental Impact: Compounds with similar structures can exhibit significant environmental persistence, highlighting the importance of studying their degradation pathways and ecological effects.

In summary, 3-(3,4-dichlorophenyl)-1-[6-[2-(dimethylamino)ethoxy]-4,7-dimethoxy-benzofuran-5-yl]prop-2-en-1-one is a compelling subject for research due to its structural uniqueness and potential applications in medicine and environmental science. As chemists continue to explore its properties, we may uncover new functionalities and applications that could impact various fields.