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Diclofenac

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Identification
Molecular formula
C14H11Cl2NO2
CAS number
15307-86-5
IUPAC name
3-(3,4-dichlorophenyl)-2H-1,3-benzoxazin-4-one
State
State

At room temperature, diclofenac is in a solid state. It is stable under normal conditions and typically provided in tablet or powder form for medicinal purposes.

Melting point (Celsius)
159.00
Melting point (Kelvin)
432.00
Boiling point (Celsius)
370.00
Boiling point (Kelvin)
643.00
General information
Molecular weight
296.15g/mol
Molar mass
296.1490g/mol
Density
1.6000g/cm3
Appearence

Diclofenac appears as a yellowish, crystalline solid. Its appearance can vary slightly, but it is typically provided in this form for pharmaceutical use. The crystalline nature allows for easy identification under a microscope.

Comment on solubility

Solubility of 3-(3,4-dichlorophenyl)-2H-1,3-benzoxazin-4-one

The solubility of the compound 3-(3,4-dichlorophenyl)-2H-1,3-benzoxazin-4-one can be influenced by various factors including temperature, pH, and the presence of other solutes. Understanding its solubility characteristics can provide important insights into its behavior in different environments.

Key Solubility Factors:

  • Polarity: The molecular structure contains both polar and non-polar regions, which can affect its overall solubility in polar or non-polar solvents.
  • Temperature: As with many organic compounds, an increase in temperature typically enhances solubility, allowing more of the substance to dissolve in a solvent.
  • pH Level: The solubility may vary significantly depending on the acidity or basicity of the solution, which could protonate or deprotonate functional groups within the compound.

In general, compounds like 3-(3,4-dichlorophenyl)-2H-1,3-benzoxazin-4-one may exhibit limited solubility in water but could be more soluble in organic solvents such as ethanol or acetone. Lab experiments should be conducted to precisely determine the solubility limits and behavior in different solvents.

Overall, understanding solubility is paramount in applications ranging from pharmaceuticals to environmental science, making the study of 3-(3,4-dichlorophenyl)-2H-1,3-benzoxazin-4-one crucial for its effective utilization.

Interesting facts

Interesting Facts about 3-(3,4-Dichlorophenyl)-2H-1,3-benzoxazin-4-one

The compound 3-(3,4-dichlorophenyl)-2H-1,3-benzoxazin-4-one, commonly researched for its potential pharmacological properties, belongs to a class of organic compounds that demonstrate remarkable versatility. Here are some intriguing aspects of this compound:

  • Structure and Function: This compound contains a benzoxazinone core, which is known for its ability to engage in various chemical reactions, making it significant in organic synthesis.
  • Antimicrobial Activity: Studies have indicated that benzoxazinone derivatives can exhibit antimicrobial properties, suggesting possible applications in developing new antibiotics.
  • Inhibition of Cancer Cell Growth: Some derivatives, including this compound, have shown promise in inhibiting the proliferation of cancer cells. This opens avenues for research in cancer therapy.
  • Role as a Plant Defense Compound: Benzoxazinones play a crucial role in plants as natural defense agents against herbivores and pathogens, highlighting their importance in plant chemistry.
  • Pharmacophore Elucidation: This compound is often involved in designing new drug candidates by elucidating its pharmacophoric features, which can lead to the discovery of more effective pharmaceuticals.

As noted by researchers, "Understanding the molecular behavior of such compounds can lead to breakthroughs in medicinal chemistry." With its diverse applications and intriguing properties, 3-(3,4-dichlorophenyl)-2H-1,3-benzoxazin-4-one represents a critical component in the ongoing exploration of novel therapeutic agents.

Synonyms
20972-99-0
BRN 1588454
4H-1,3-BENZOXAZIN-4-ONE, 3-(3,4-DICHLOROPHENYL)-2,3-DIHYDRO-
DTXSID90175155
3-(3,4-Dichlorophenyl)-2,3-dihydro-4H-1,3-benzoxazin-4-one
DTXCID7097646
RefChem:297035