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Diclofenac

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Identification
Molecular formula
C14H11Cl2NO2
CAS number
15307-86-5
IUPAC name
3-(3,4-dichlorophenyl)prop-2-enoic acid
State
State

At room temperature, diclofenac is typically found as a solid. It is often processed into tablets or capsules for medicinal use. Its solid-state is stable under normal conditions.

Melting point (Celsius)
283.00
Melting point (Kelvin)
556.15
Boiling point (Celsius)
345.60
Boiling point (Kelvin)
618.75
General information
Molecular weight
296.15g/mol
Molar mass
296.1480g/mol
Density
1.2140g/cm3
Appearence

Diclofenac appears as a white or slightly yellowish crystalline powder with no significant odor. It is often supplied in the form of a sodium or potassium salt, which can alter its appearance slightly but usually remains in a similar powder form.

Comment on solubility

Solubility of 3-(3,4-dichlorophenyl)prop-2-enoic acid

The solubility of 3-(3,4-dichlorophenyl)prop-2-enoic acid is a noteworthy characteristic, significantly influenced by its molecular structure. This compound, a derivative of a phenylpropanoic acid, displays unique solubility behavior in various solvents.

Key Points on Solubility:

  • Polar Solvents: The presence of the carboxylic acid group (-COOH) enhances solubility in polar solvents such as water, due to hydrogen bonding interactions.
  • Non-polar Solvents: Conversely, when introduced to non-polar solvents, the solubility decreases markedly, highlighting the compound's partial hydrophobic nature from the chlorine substituents on the phenyl ring.
  • Temperature Influence: Like many organic acids, solubility can be increased with temperature. Higher temperatures often lead to increased solvation and dissolution rates.

In conclusion, the solubility of 3-(3,4-dichlorophenyl)prop-2-enoic acid can be summarized as favorably soluble in water and other polar solvents, but exhibiting limited solubility in non-polar environments. This behavior showcases the compound's versatility and potential applications in diverse chemical environments. As noted, "Solubility is the key to reactivity!"

Interesting facts

Interesting Facts about 3-(3,4-Dichlorophenyl)prop-2-enoic Acid

3-(3,4-Dichlorophenyl)prop-2-enoic acid, commonly referred to as a derivative of phenylpropanoic acid, presents a compelling subject for study due to its noteworthy features and applications:

  • Biological Significance: This compound belongs to a class of chemicals known for their significant biological activity, particularly in agricultural and pharmaceutical contexts. Its structure suggests potential herbicidal properties, making it of interest in agrochemical research.
  • Synthesis Insights: The synthesis of this compound often involves aromatic substitution reactions, showcasing the versatility of electrophilic aromatic substitution methods in organic chemistry. As a student, understanding these synthesis pathways can deepen one’s grasp of functional group reactivity.
  • Environmental Impact: The dichlorophenyl group implies that this compound may persist in the environment. Consequently, studies often focus on the compound's environmental fate and its breakdown products, which can pose risks to ecosystems.
  • Analytical Techniques: Characterizing 3-(3,4-Dichlorophenyl)prop-2-enoic acid presents a brilliant opportunity for students to learn analytical techniques such as NMR, IR, and mass spectrometry. These techniques are vital for confirming the compound's structure.

A fascinating quote by renowned chemist Linus Pauling emphasizes the importance of chemical research: “The best way to have a good idea is to have a lot of ideas.” Studying compounds like 3-(3,4-Dichlorophenyl)prop-2-enoic acid highlights the creativity involved in chemical science and the importance of interdisciplinary studies.

Overall, this compound is not only significant in theoretical chemistry but also has practical implications that can drive forward research in sustainable practices and bioactivity.

Synonyms
3-(3,4-dichlorophenyl)prop-2-enoic acid
Enamine_005463
3,4-dichloro cinnamic acid
3,4-dichloro-cinnamic acid
RRLUFPHCTSFKNR-UHFFFAOYSA-N
STR02636
AKOS025243220
PS-7921
SY015682
3-(3,4-dichlorophenyl)-2-propeneoic acid
DB-021862
NS00044750