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Amfonelic acid

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Identification
Molecular formula
C23H25NO
CAS number
15180-02-6
IUPAC name
3-(3,4-dihydro-1H-isoquinolin-2-yl)-1,1-diphenyl-butan-1-ol
State
State

Amfonelic acid is typically found in a solid state at room temperature, exhibiting characteristics of a crystalline powder.

Melting point (Celsius)
216.00
Melting point (Kelvin)
489.15
Boiling point (Celsius)
505.15
Boiling point (Kelvin)
778.30
General information
Molecular weight
333.44g/mol
Molar mass
333.4380g/mol
Density
1.2000g/cm3
Appearence

Amfonelic acid appears as a white to off-white crystalline powder. It is usually odorless and is stable under normal conditions.

Comment on solubility

Solubility of 3-(3,4-dihydro-1H-isoquinolin-2-yl)-1,1-diphenyl-butan-1-ol

The solubility of 3-(3,4-dihydro-1H-isoquinolin-2-yl)-1,1-diphenyl-butan-1-ol is influenced by its unique chemical structure, which combines hydrophobic and hydrophilic characteristics. Generally, this compound is expected to exhibit:

  • Moderate Solubility in Organic Solvents: Due to the presence of multiple phenyl groups and an isoquinoline moiety, it is more soluble in non-polar organic solvents such as ethanol, methanol, and dichloromethane.
  • Poor Solubility in Water: The bulky diphenyl and isoquinoline groups render it largely insoluble in aqueous solutions. Water's polar nature does not favor interaction with the hydrophobic regions of the compound.
  • Temperature Dependency: Solubility may increase with temperature, as is common with many organic compounds, allowing for increased kinetic energy and potential solvation.

It is often noted that compounds with mixed polarities exhibit complex solubility behaviors:

  1. Ionization can occur under specific pH conditions, potentially facilitating solubility in water.
  2. Amphiphilic properties may lead to micelle formation at higher concentrations, aiding in dispersal in some cases.

In summary, the solubility of this compound serves as a reminder of the intricate relationship between chemical structure and solvent interactions, as each component plays a crucial role in determining its overall solubility profile.

Interesting facts

Interesting Facts About 3-(3,4-dihydro-1H-isoquinolin-2-yl)-1,1-diphenyl-butan-1-ol

This intriguing compound, characterized by its complex structure, is a prime example of the fascinating world of organic chemistry. Here are some notable aspects:

  • Pharmacological Potential: Due to its isoquinoline moiety, this compound may exhibit various biological activities. Isoquinolines are known for their roles in medicinal chemistry, with implications in promoting neuroprotective effects.
  • Synthesis Challenges: The synthesis of this compound can be particularly challenging due to the stereochemistry associated with the butanol group, requiring precise conditions to yield the desired product without unwanted by-products.
  • Structure-Activity Relationship (SAR): Understanding the SAR of this compound can lead to the development of more potent analogs. The presence of the diphenyl group could enhance the lipophilicity of the compound, influencing its bioavailability.
  • Multi-Functional Properties: Beyond its pharmacological properties, the presence of multiple functional groups suggests that this compound may have potential applications in materials science or as a building block for further chemical syntheses.

As a scientist or an aspiring chemist, one must appreciate the intricate details that certain compounds like this can offer in terms of practical applications and insights into molecular behavior. The exploration of such compounds not only enriches our understanding of chemical interactions but also opens up avenues for innovative drug design.

Synonyms
4082-44-4
3,4-Dihydro-alpha,alpha-diphenyl-gamma-methyl-2(1H)-isoquinolinepropanol
BRN 1438746
2(1H)-ISOQUINOLINEPROPANOL, 3,4-DIHYDRO-alpha,alpha-DIPHENYL-gamma-METHYL-
DTXSID20961240
3-(3,4-dihydroisoquinolin-2(1H)-yl)-1,1-diphenylbutan-1-ol