Skip to main content

Diphenylprolinol

ADVERTISEMENT
Identification
Molecular formula
C19H21NO
CAS number
22348-32-9
IUPAC name
3-(3,4-dihydro-1H-isoquinolin-2-yl)-1,1-diphenyl-propan-1-ol
State
State

At room temperature, Diphenylprolinol exists as a solid.

Melting point (Celsius)
98.00
Melting point (Kelvin)
371.20
Boiling point (Celsius)
457.10
Boiling point (Kelvin)
730.30
General information
Molecular weight
309.42g/mol
Molar mass
309.4170g/mol
Density
1.1620g/cm3
Appearence

Diphenylprolinol typically appears as a white or off-white crystalline solid. It is slightly viscous in texture.

Comment on solubility

Solubility of 3-(3,4-dihydro-1H-isoquinolin-2-yl)-1,1-diphenyl-propan-1-ol

The solubility of the compound 3-(3,4-dihydro-1H-isoquinolin-2-yl)-1,1-diphenyl-propan-1-ol can be characterized as follows:

  • Polarity: The presence of both hydroxy (-OH) and aromatic groups contributes to a moderate polarity, which typically influences solubility in different solvents.
  • Solvent Preference: It is likely to be more soluble in polar solvents such as:
    • Water – due to the hydroxy group
    • Methanol
    • Ethanol
  • Insolubility in Non-Polar Solvents: Compounds with significant aromatic character may exhibit low solubility in non-polar solvents like hexane or toluene.
  • Temperature Effects: The solubility may increase with temperature, which is common for many organic compounds.
  • Intramolecular Interactions: Hydrogen bonding within the molecule can also play a role in solubility, potentially affecting its ability to dissolve in various media.

In summary, while predicting the exact solubility requires experimental data, the combination of polar and nonpolar characteristics in this compound suggests variable solubility across different environments. Understanding the solubility of such compounds is essential for their applications in pharmaceuticals and materials science.

Interesting facts

Interesting Facts about 3-(3,4-dihydro-1H-isoquinolin-2-yl)-1,1-diphenyl-propan-1-ol

The compound 3-(3,4-dihydro-1H-isoquinolin-2-yl)-1,1-diphenyl-propan-1-ol is a fascinating entity in the field of organic chemistry, particularly noted for its structural complexity and potential applications. Below are some intriguing insights into this compound:

  • Structural Features: This compound contains a 1,1-diphenyl group, which plays a significant role in its chemical properties and interactions. The presence of the isoquinoline moiety further adds to its structural diversity and may influence its biological activity.
  • Biological Relevance: Compounds with isoquinoline derivatives have been investigated for their potential biological activities, including antimicrobial, anticancer, and neuroprotective effects. This compound's unique structure may contribute to similar pharmacological profiles.
  • Synthetic Interest: The synthesis of this compound could involve various organic chemistry techniques, including reduction, coupling reactions, and functional group modifications. Its synthesis offers an excellent opportunity for students to engage in laboratory practices enhancing their understanding of organic reactions.
  • Applications: Given its potential biological activity, this compound could serve as a key molecule in drug discovery and development. Researchers are increasingly looking to synthesize and modify such compounds to create better therapeutic agents.
  • Multifunctionality: The multifunctionality of this compound, stemming from its structural composition, positions it as a candidate for studies in various fields, including medicinal chemistry, materials science, and biochemistry.

In conclusion, the compound 3-(3,4-dihydro-1H-isoquinolin-2-yl)-1,1-diphenyl-propan-1-ol exemplifies the richness of organic compounds in chemistry, offering exciting avenues for research and application. Its complexity not only intrigues scientists but also represents a valuable resource for the exploration of new therapeutic agents.

Synonyms
BRN 1438037
2(1H)-ISOQUINOLINEPROPANOL, 3,4-DIHYDRO-alpha,alpha-DIPHENYL-
3,4-Dihydro-alpha,alpha-diphenyl-2(1H)-isoquinolinepropanol
3518-96-5
DTXSID60188671
2-(3,3-Diphenyl-3-hydroxypropyl)-1,2,3,4-tetrahydroisoquinoline
5-20-06-00327 (Beilstein Handbook Reference)
DTXCID20111162