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Forskolin

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Identification
Molecular formula
C22H34O7
CAS number
66575-29-9
IUPAC name
3-[(3,4-dihydroxyphenyl)-hydroxy-methylene]-1-(2-isopropenyl-5-methyl-hex-4-enyl)-6,6-dimethyl-5,7-bis(3-methylbut-2-enyl)bicyclo[3.3.1]nonane-2,4,9-trione
State
State

At room temperature, Forskolin is typically found as a solid.

Melting point (Celsius)
233.00
Melting point (Kelvin)
506.15
Boiling point (Celsius)
841.30
Boiling point (Kelvin)
1 114.45
General information
Molecular weight
410.50g/mol
Molar mass
410.4970g/mol
Density
1.2603g/cm3
Appearence

Forskolin appears as a yellow-brown powder or an amorphous solid, depending on its purity and preparation method. It is known for its bitter taste and strong aromatic odor.

Comment on solubility

Solubility of C22H34O7

The solubility of the compound 3-[(3,4-dihydroxyphenyl)-hydroxy-methylene]-1-(2-isopropenyl-5-methyl-hex-4-enyl)-6,6-dimethyl-5,7-bis(3-methylbut-2-enyl)bicyclo[3.3.1]nonane-2,4,9-trione can be a complex topic due to its intricate molecular structure. Here are several key points regarding its solubility:

  • Solvent Compatibility: This compound is likely to exhibit varying solubility depending on the solvent due to its hydrophilic and hydrophobic regions. Organic solvents may enhance solubility compared to polar solvents.
  • Influence of Functional Groups: The presence of multiple hydroxyl groups suggests a tendency towards solubility in water, but steric hindrance from bulky hydrophobic portions may counterbalance this effect.
  • Temperature Effects: Increased temperature often improves the solubility of organic compounds. Therefore, testing the solubility at varying temperatures could yield varying results.
  • pH Sensitivity: The solubility may also be pH-dependent, as changes in acidity can influence the ionization of hydroxyl groups, thereby affecting solubility.

In conclusion, while the solubility of C22H34O7 is not straightforward and can be influenced by numerous factors, exploring its solubility profile in different conditions will be essential for practical applications. As with many complex organic compounds, an empirical approach often leads to the most accurate understanding of solubility behavior.

Interesting facts

Interesting Facts about 3-[(3,4-Dihydroxyphenyl)-hydroxy-methylene]-1-(2-isopropenyl-5-methyl-hex-4-enyl)-6,6-dimethyl-5,7-bis(3-methylbut-2-enyl)bicyclo[3.3.1]nonane-2,4,9-trione

This complex organic compound is notable for several intriguing reasons. In the vast realm of organic chemistry, compounds of this nature often exhibit unique properties that can have significant biological implications. Here are some key points to consider:

  • Natural Product Origins: This compound is derived from natural sources and may exhibit features characteristic of plant-derived substances, contributing to their potential medicinal properties.
  • Structural Complexity: Its intricate bicyclic structure showcases the fascinating versatility of carbon chains, exemplifying how slight variations in structure can lead to diverse functions.
  • Bioactivity: Compounds with similar frameworks have been studied for their anti-inflammatory, antioxidant, and anticancer activities, demonstrating the potential benefits of phytochemicals in health.
  • Synthetic Challenges: The synthesis of such molecules often presents unique challenges, requiring advanced organic synthesis techniques to manipulate the multiple functional groups effectively.
  • Analytical Importance: Understanding the characteristics and behavior of compounds like this one aids in developing analytical techniques crucial for identifying and quantifying similar biologically active substances.

As a chemistry student, exploring compounds like this can be both challenging and rewarding. The study of such compounds not only enhances our understanding of chemical reactivity and structure but also opens doors to novel therapeutic agents that could revolutionize the field of medicine.

Ultimately, the investigation of complex compounds like this one highlights the beauty of chemistry and its profound impact on science and society.

Synonyms
Garcinol
Camboginol
78824-30-3
CID 5281560
3-(3,4-dihydroxybenzoyl)-4-hydroxy-8,8-dimethyl-5-[5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl]-1,7-bis(3-methylbut-2-en-1-yl)bicyclo[3.3.1]non-3-ene-2,9-dione