Skip to main content

3-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline

ADVERTISEMENT
Identification
Molecular formula
C20H23NO4
CAS number
121-66-4
IUPAC name
3-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline
State
State

At room temperature, 3-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline is typically in a solid state. It is often encountered as a crystalline powder under ambient conditions. Proper storage in a cool, dry place is recommended to maintain its solid form and prevent degradation.

Melting point (Celsius)
67.00
Melting point (Kelvin)
340.15
Boiling point (Celsius)
428.50
Boiling point (Kelvin)
701.60
General information
Molecular weight
327.37g/mol
Molar mass
327.3740g/mol
Density
1.1400g/cm3
Appearence

The compound typically appears as an off-white to pale yellow crystalline powder. It may exhibit slight hygroscopic properties, absorbing small amounts of moisture when exposed to air. The crystals should be free of any visual impurities when pure.

Comment on solubility

Solubility of 3-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline

The solubility of the compound 3-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline is an important aspect to consider when evaluating its chemical behavior and potential applications. Here are some key points regarding its solubility:

  • Polarity: Due to the presence of multiple methoxy groups, this compound exhibits a degree of polarity which can enhance its solubility in polar solvents such as methanol and ethanol.
  • Non-polar Solvents: Conversely, it may show limited solubility in non-polar solvents such as hexane, owing to the aromatic structure that might favor interactions with polar environments.
  • Temperature Dependency: As with many organic compounds, solubility can increase with temperature. Thus, heating the solvent may facilitate better dissolution of the compound.
  • pH Influence: The solubility can also be affected by the pH of the solution, especially if the compound has functional groups that can be protonated or deprotonated.

In conclusion, while comprehensive data may be lacking, understanding the factors influencing the solubility of 3-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline can provide insights into its behavior in different environments and its potential uses in various applications.

Interesting facts

Interesting Facts about 3-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline

This fascinating compound, belonging to the isoquinoline class of alkaloids, showcases an intricate blend of structure and potential applications that captures the interest of chemists and pharmacologists alike.

Structural Highlights

  • Functional Groups: The presence of multiple methoxy groups (−OCH3) enhances its solubility and reactivity, making it a versatile building block in synthetic chemistry.
  • Stereochemistry: The dihydroisoquinoline structure introduces chirality, leading to possible stereoisomers that may exhibit different biological activities.

Potential Applications

This compound is not just a theoretical curiosity; its unique structure suggests several promising avenues for research:

  • Pharmacology: Isoquinolines have been studied for their potential therapeutic effects, including analgesic, anti-inflammatory, and anticancer properties.
  • Organic Synthesis: This compound can serve as a precursor in the synthesis of more complex medicinal compounds, making it valuable in drug development.

Research Frontiers

Scientists are continually exploring the biological significance of compounds like this one. Notable points of interest include:

  • Mechanisms of Action: Understanding how this compound interacts with biological systems can lead to new drug discoveries.
  • Synergistic Effects: Investigations into how this compound might work in synergy with other drugs can unveil enhanced therapeutic profiles.

As a synthesis enthusiast or a chemistry student diving into the world of isoquinolines, the study of 3-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline can open up exciting pathways of exploration and innovation in both academic and practical applications.

Synonyms
20232-49-9
BRN 0320596
ISOQUINOLINE, 3,4-DIHYDRO-6,7-DIMETHOXY-3-VERATRYL-
3,4-Dihydro-6,7-dimethoxy-3-veratrylisoquinoline
4-21-00-02740 (Beilstein Handbook Reference)
RefChem:350025
3-(3,4-dimethoxybenzyl)-6,7-dimethoxy-3,4-dihydroisoquinoline
DTXSID50942340
3-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline