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CRL-40,941

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Identification
Molecular formula
C19H30N2O2
CAS number
90212-80-9
IUPAC name
3-(3,5-dimethylisoxazol-4-yl)-N-(7,7-dimethylnorbornan-2-yl)-N-methyl-propanamide
State
State

At room temperature, this compound is in a solid state.

Melting point (Celsius)
141.00
Melting point (Kelvin)
414.15
Boiling point (Celsius)
430.00
Boiling point (Kelvin)
703.15
General information
Molecular weight
332.46g/mol
Molar mass
332.4600g/mol
Density
1.1300g/cm3
Appearence

The compound is typically found as a white or off-white crystalline solid.

Comment on solubility

Solubility of 3-(3,5-dimethylisoxazol-4-yl)-N-(7,7-dimethylnorbornan-2-yl)-N-methyl-propanamide

The solubility of a compound like 3-(3,5-dimethylisoxazol-4-yl)-N-(7,7-dimethylnorbornan-2-yl)-N-methyl-propanamide can be influenced by several factors, including its molecular structure and the nature of the functional groups present. This compound, which contains both hydrophobic and hydrophilic elements, exhibits interesting solubility characteristics.

Key Solubility Factors:

  • Molecular Polarity: The presence of polar functional groups can enhance solubility in polar solvents, such as water.
  • Hydrophobic Interactions: The dimethylnorbornan moiety may lead to low solubility in aqueous environments due to its hydrophobic nature.
  • Hydrogen Bonding: Capable of forming hydrogen bonds, the molecule may dissolve better in solvents that can donate or accept hydrogen bonds.
  • Temperature Effects: Increasing temperature can potentially improve solubility for many organic compounds.

In summary, while 3-(3,5-dimethylisoxazol-4-yl)-N-(7,7-dimethylnorbornan-2-yl)-N-methyl-propanamide presents a complex solubility profile, its actual solubility would need to be determined experimentally in various solvents including polar and nonpolar environments. Understanding the balance of hydrophobic and hydrophilic properties is essential for predicting its solubility behavior in real-world applications.

Interesting facts

Interesting Facts about 3-(3,5-Dimethylisoxazol-4-yl)-N-(7,7-dimethylnorbornan-2-yl)-N-methyl-propanamide

This intriguing compound is known for its unique structure and potential applications in medicinal chemistry. Here are some fascinating insights:

  • Structural Complexity: The compound features a dimethylisoxazole moiety which is a five-membered ring known for its involvement in various biological activities, including anti-inflammatory and antimicrobial properties.
  • Chiral Centers: The presence of the norbornan framework introduces chirality. Chirality is significant in pharmaceuticals as it can affect the biological activity of drugs, often leading to different therapeutic effects.
  • Potential Applications: Compounds with similar structures are often explored for their capabilities as pharmacological agents. This particular compound may display activities such as analgesic or anti-anxiety effects, making it a candidate for drug development.
  • Isomer Variability: The specific arrangement of substituents can lead to different isomers, which may have varying biological effects. This variability underscores the importance of precise synthesis and characterization in drug development.
  • Research Interest: The intersection of isoxazoles and terpenes (like the dimethylnorbornane) continues to attract significant research interest due to their diverse biological activities and potential in creating novel therapeutic agents.

Overall, 3-(3,5-dimethylisoxazol-4-yl)-N-(7,7-dimethylnorbornan-2-yl)-N-methyl-propanamide represents a fascinating intersection of organic chemistry and pharmacology, paving the way for new discoveries and applications in the field of medicinal chemistry.

Synonyms
(+-)-endo-N-2-Bornyl-3,5-dimethyl-4-isoxazolepropionamide
24629-83-2
4-ISOXAZOLEPROPIONAMIDE, N-2-BORNYL-3,5-DIMETHYL-, endo-(+-)-
RefChem:293704
DTXSID50947552
N-(7,7-Dimethylbicyclo[2.2.1]heptan-2-yl)-3-(3,5-dimethyl-1,2-oxazol-4-yl)-N-methylpropanamide