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Withanolide A

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Identification
Molecular formula
C28H38O6
CAS number
264624-62-2
IUPAC name
3-[(3R,6R,7R,11S,14S,16R)-14-hydroxy-7,11-dimethyl-2-oxapentacyclo[8.8.0.01,3.03,7.011,16]octadecan-6-yl]-2H-furan-5-one
State
State

Withanolide A is generally in a solid state at room temperature.

Melting point (Celsius)
224.00
Melting point (Kelvin)
497.15
Boiling point (Celsius)
488.15
Boiling point (Kelvin)
761.15
General information
Molecular weight
470.63g/mol
Molar mass
470.6300g/mol
Density
1.2005g/cm3
Appearence

Withanolide A is generally obtained as a crystalline solid. Its appearance shows a characteristic crystalline structure, often white or off-white in color, typical of terpene-derived compounds.

Comment on solubility

Solubility of 3-[(3R,6R,7R,11S,14S,16R)-14-hydroxy-7,11-dimethyl-2-oxapentacyclo[8.8.0.01,3.03,7.011,16]octadecan-6-yl]-2H-furan-5-one

The solubility of complex organic compounds like 3-[(3R,6R,7R,11S,14S,16R)-14-hydroxy-7,11-dimethyl-2-oxapentacyclo[8.8.0.01,3.03,7.011,16]octadecan-6-yl]-2H-furan-5-one can present unique challenges. These types of molecules often demonstrate varying degrees of solubility based on several factors:

  • Polarity: The presence of functional groups, such as the hydroxy group, can enhance solubility in polar solvents.
  • Molecular Structure: Complex ringed structures may affect how well the compound interacts with solvents, often leading to lower solubility in typical solvents.
  • Temperature: Increased temperature can improve solubility for many organic compounds.
  • Solvent Type: Different solvents (e.g., water, ethanol, acetone) can elicit different solubility behaviors due to their unique properties.

It’s important to note that while some compounds are soluble in water or common organic solvents, others may remain largely insoluble due to their intricate structural features. As a general guideline, exploring solubility in a variety of solvents and conditions is recommended.

In conclusion, understanding the solubility of complex compounds like this one involves a blend of chemical intuition and experimental observation. As scientifically stated, "The solubility of a compound is often as unique as its structure."

Interesting facts

Interesting Facts about 3-[(3R,6R,7R,11S,14S,16R)-14-hydroxy-7,11-dimethyl-2-oxapentacyclo[8.8.0.01,3.03,7.011,16]octadecan-6-yl]-2H-furan-5-one

This compound is a fascinating example of a natural product with potential medicinal properties. As a member of the furan class of compounds, it exhibits a variety of biological activities that are of significant interest in the field of medicinal chemistry. Here are some notable points:

  • Complex Structure: The intricate structure of this compound showcases a pentacyclic framework, making it an intriguing subject for structural analysis and synthesis studies.
  • Biological Activity: Research suggests that compounds like this one may possess antitumor and antimicrobial properties, which opens avenues for novel drug development.
  • Stereochemistry: The detailed stereochemistry indicated by the (3R,6R,7R,11S,14S,16R) configuration highlights the stereospecific nature of its biological activity, emphasizing the importance of chirality in medicinal compounds.
  • Natural Occurrence: Compounds similar to this one are often derived from plant sources, indicating their role in traditional medicine and their potential as leads for new therapeutic agents.
  • Furan Derivative: As a furan derivative, it belongs to a class of compounds that are known for their involvement in numerous chemical reactions, including electrophilic aromatic substitutions.

Overall, the study of this compound not only illuminates the realm of organic synthesis and structure-activity relationships but also emphasizes the continual search for new medicinal therapies derived from nature. As scientists delve deeper into the properties and applications of such compounds, they may unearth transformative insights into drug discovery and development.

Synonyms
DTXSID90978027
3-Hydroxy-8,14-epoxycard-20(22)-enolide