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Spiramycin

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Identification
Molecular formula
C43H74N2O14
CAS number
8025-81-8
IUPAC name
3-[(3S,5R,8R,9S,10S,12R,13S,14S)-3-[(2R,4S,5S,6R)-5-[(2S,4S,5S,6R)-5-[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-4-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-4-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-12,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one
State
State

At room temperature, spiramycin is typically in a solid state. It is usually provided as a powder for pharmaceutical use and is known for being stable under normal conditions.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
301.80
Boiling point (Kelvin)
574.95
General information
Molecular weight
843.05g/mol
Molar mass
843.0520g/mol
Density
1.2810g/cm3
Appearence

Spiramycin appears as a white to pale yellow crystalline powder. It is known for its solubility in water and has a faint, characteristic odor.

Comment on solubility

Solubility Characteristics

The compound with the complex name 3-[(3S,5R,8R,9S,10S,12R,13S,14S)-3-[(2R,4S,5S,6R)-5-[(2S,4S,5S,6R)-5-[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-4-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-4-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-12,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one is a highly polar and complex organic molecule. Its solubility can be influenced by several key factors:

  • Polarity: Due to the presence of multiple hydroxyl groups, this compound exhibits high polarity, which generally enhances its solubility in polar solvents such as water.
  • Hydrogen Bonding: The various hydroxyl (-OH) functional groups can engage in hydrogen bonding, further aiding its solubility in aqueous environments.
  • Hydrophobic Interactions: Conversely, the hydrophobic regions of the molecule can limit its solubility in polar solvents while potentially enhancing solubility in non-polar organic solvents.
  • Conformational Dynamics: The complex three-dimensional structure may affect how the compound interacts with solvents, potentially leading to variable solubility behavior depending on the specific conformations adopted.

As a result, while this compound may exhibit favorable solubility in certain polar solvents, its overall solubility profile remains complex and may require consideration of specific conditions such as pH, temperature, and the presence of other solutes.

Interesting facts

Exploring the Complexities of a Unique Compound

This fascinating compound, known for its intricate structure, offers a plethora of interesting scientific insights. As a scientist studying this compound, you would discover a wide variety of intriguing features, including:

  • Stereochemistry: The molecule boasts a rich stereochemical landscape, with numerous chiral centers contributing to its unique three-dimensional configuration and influencing its biological activity.
  • Natural Derivation: This compound is often derived from natural sources, hinting at its potential role in various biological processes and its importance in natural product chemistry.
  • Biological Relevance: With its complex ring structures, there is potential for interesting interactions with biomolecules, making it a candidate for research in pharmacology and medicinal chemistry.
  • Functional Groups: The presence of multiple hydroxyl (-OH) groups suggests enhanced polarity, which could impact its solubility and reactivity, providing a foundation for further functionalization.

As a chemistry student, you might also appreciate the methodical nature of determining the compound’s properties through various analytical techniques. There is a strong emphasis on understanding how subtle changes in the molecular structure can significantly affect the compound's behavior and applications.

Moreover, this compound exemplifies the beauty of organic chemistry, showcasing how complexity can arise from simple building blocks through selective reactions and stereochemical arrangements. Embrace the elegance of chemistry while navigating through the intricacies of this compound!

Synonyms
CHEMBL49693
SCHEMBL18947799
HMS3259A12
NC00559
NCGC00247770-01
BRD-A75144621-001-01-0
4-((3S,5R,8R,9S,10S,12R,13S,14S,17R)-3-((2R,4S,5S,6R)-5-((2S,4S,5S,6R)-5-((2S,4S,5S,6R)-4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-12,14-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)furan-2(5H)-one