Skip to main content

Tafamidis

ADVERTISEMENT
Identification
Molecular formula
C31H24F2N2O9
CAS number
603132-23-8
IUPAC name
3-[4-[2-[[6-amino-9-[5-(ethylcarbamoyl)-3,4-dihydroxy-tetrahydrofuran-2-yl]purin-2-yl]amino]ethyl]phenyl]propanoic acid
State
State

At room temperature, tafamidis is a solid powder. It remains stable at ambient conditions and is used primarily in pharmaceutical applications.

Melting point (Celsius)
118.50
Melting point (Kelvin)
391.65
Boiling point (Celsius)
746.79
Boiling point (Kelvin)
1 019.94
General information
Molecular weight
905.90g/mol
Molar mass
905.8970g/mol
Density
1.5103g/cm3
Appearence
Tafamidis is typically a solid compound with a crystalline structure. It is a white to off-white powder that may appear in a dry form. The crystallinity is a notable characteristic, often lending to its stability and solubility properties in pharmaceutical formulations.
Comment on solubility

Solubility Considerations for 3-[4-[2-[[6-amino-9-[5-(ethylcarbamoyl)-3,4-dihydroxy-tetrahydrofuran-2-yl]purin-2-yl]amino]ethyl]phenyl]propanoic acid

The solubility of a compound is crucial for its applicability in various fields such as pharmaceuticals, agriculture, and materials science. In the case of 3-[4-[2-[[6-amino-9-[5-(ethylcarbamoyl)-3,4-dihydroxy-tetrahydrofuran-2-yl]purin-2-yl]amino]ethyl]phenyl]propanoic acid, represented by the formula C31H24F2N2O9, several solubility factors come into play:

  • Polarity: The presence of multiple functional groups, including amino and hydroxyl groups, may contribute to its polarity, potentially enhancing solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds can significantly affect solubility. The compound's functional groups are likely to engage in hydrogen bonding with solvents, further influencing solubility.
  • Solvent Compatibility: It is essential to consider the compatibility of the compound with various solvents. Solubility may vary dramatically between organic and aqueous solutions.
  • Structural Complexity: The intricate structure of the compound could limit solubility in certain environments, especially if there are steric hindrances that impede solvent interaction.

As a summary, the solubility of 3-[4-[2-[[6-amino-9-[5-(ethylcarbamoyl)-3,4-dihydroxy-tetrahydrofuran-2-yl]purin-2-yl]amino]ethyl]phenyl]propanoic acid will likely hinge on its polarity, the ability to form hydrogen bonds, and the nature of the solvent. Understanding these factors is key to predicting its behavior in solution.

Interesting facts

Interesting Facts about 3-[4-[2-[[6-amino-9-[5-(ethylcarbamoyl)-3,4-dihydroxy-tetrahydrofuran-2-yl]purin-2-yl]amino]ethyl]phenyl]propanoic acid

This compound, often referred to in scientific literature as a novel pharmaceutical agent, is a complex molecule with a variety of intriguing features:

  • Biological Significance: This compound has shown potential in biomedical applications, particularly in drug design aimed at targeting specific cellular pathways.
  • Structural Complexity: Its intricate structure incorporates multiple functional groups, making it an interesting subject for studies in medicinal chemistry.
  • Target Interactions: The unique configuration allows it to interact with various biological receptors, enhancing its efficacy in therapeutic scenarios, especially in cancer research.
  • Synthetic Challenges: Synthesizing such a compound poses considerable challenges, typically requiring multiple reaction steps and careful control of conditions to ensure purity and yield.

As quoted by researchers in the field, “The synthesis and characterization of complex pharmaceuticals serve as the backbone of effective drug development.” This underscores the importance of compounds like 3-[4-[2-[[6-amino-9-[5-(ethylcarbamoyl)-3,4-dihydroxy-tetrahydrofuran-2-yl]purin-2-yl]amino]ethyl]phenyl]propanoic acid in modern chemistry.

In conclusion, studying such compounds not only offers insights into molecular interactions but also fuels innovation in therapeutic strategies, making it a fascinating area of focus for both chemists and medical researchers alike.

Synonyms
3-[4-[2-[[6-amino-9-[5-(ethylcarbamoyl)-3,4-dihydroxy-2-oxolanyl]-2-purinyl]amino]ethyl]phenyl]propanoic acid
3-[4-[2-[[6-amino-9-[5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]amino]ethyl]phenyl]propanoic acid
Benzenepropanoic acid, 4-[2-[[6-amino-9-(N-ethyl-beta-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]-
3-{4-[2-({6-amino-9-[5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl}amino)ethyl]phenyl}propanoic acid
3-{4-[2-({6-AMINO-9-[(2R,3R,4S,5S)-5-(ETHYLCARBAMOYL)-3,4-DIHYDROXYOXOLAN-2-YL]PURIN-2-YL}AMINO)ETHYL]PHENYL}PROPANOIC ACID HYDROCHLORIDE
CHEMBL281213
SCHEMBL3730487
BDBM86760
CHEBI:91896
DTXSID10861260
CAS_104924
NSC_104924
SB19557
NCGC00015187-02
L000177
BRD-A81866333-003-01-5
Q27163693
3-{4-[2-({6-Amino-9-[5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]-9H-purin-2-yl}amino)ethyl]phenyl}propanoic acid