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Fluoxetine

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Identification
Molecular formula
C17H18ClNO3
CAS number
54910-89-3
IUPAC name
3-[4-[2-chloroethyl(2-fluoroethyl)amino]phenyl]propanoic acid
State
State

At room temperature, fluoxetine is predominantly found as a solid due to its stable crystalline structure, catering largely to pharmaceutical uses.

Melting point (Celsius)
179.00
Melting point (Kelvin)
452.15
Boiling point (Celsius)
318.00
Boiling point (Kelvin)
591.15
General information
Molecular weight
309.75g/mol
Molar mass
309.7520g/mol
Density
1.3000g/cm3
Appearence

Fluoxetine, often recognized by its applications as an antidepressant, usually appears as a white to off-white crystalline powder. It is characterized by its lack of odor and distinct crystalline nature.

Comment on solubility

Solubility of 3-[4-[2-chloroethyl(2-fluoroethyl)amino]phenyl]propanoic acid

The solubility of 3-[4-[2-chloroethyl(2-fluoroethyl)amino]phenyl]propanoic acid can be quite intricate due to its complex structure and functional groups. Understanding its solubility can be crucial for applications in pharmaceuticals and chemistry. Here are some key points to consider:

  • Polar vs. Nonpolar: This compound exhibits both polar and nonpolar characteristics due to the presence of the carboxylic acid group and the alkyl chains. This duality can lead to varying solubility in different solvents.
  • Aqueous Solubility: The carboxylic acid group typically enhances solubility in water, allowing the compound to dissociate into ions, which can facilitate interaction with other polar molecules.
  • Organic Solubility: Conversely, its nonpolar regions may decrease solubility in water but increase solubility in organic solvents, such as methanol or ethanol.
  • Influencing Factors: Solubility can also be influenced by factors such as temperature, pH, and the presence of other ions or solvents.

In conclusion, the solubility of 3-[4-[2-chloroethyl(2-fluoroethyl)amino]phenyl]propanoic acid is an essential characteristic that can determine its practical usage. Understanding the balance between its polar and nonpolar elements becomes pivotal for researchers and practitioners in the field.

Interesting facts

3-[4-[2-Chloroethyl(2-fluoroethyl)amino]phenyl]propanoic Acid

This intriguing compound belongs to a class of chemicals that exhibit **potential pharmacological properties**. Its unique structure allows for interactions with biological systems that can be both fascinating and critical for medicinal chemistry.

Key Points of Interest:

  • Pharmaceutical Potential: Compounds with variations in alkyl chains, such as the chlorinated and fluorinated groups present here, can enhance biological activity. The presence of a chloroethyl group may impart significant efficacy in targeted drug delivery.
  • Mechanistic Insights: Molecules like this may operate as ligands that bind to specific receptors, leading to various therapeutic effects, making them potential candidates for further research in oncology and neurology.
  • Modifications Matter: The functional groups on this compound are pivotal. The fluorine in the structure not only can affect lipophilicity but also may improve metabolic stability, influencing how the body processes the compound.
  • Structure-Activity Relationship (SAR): Understanding how alterations to the basic structure impact activity can guide future modifications, making SAR studies essential for developing more effective drugs based on this scaffold.
  • Environmental Impact: Investigating compounds with halogen substituents is crucial as they can carry implications for both human health and environmental safety due to their potential persistence and bioaccumulation.

In summary, 3-[4-[2-chloroethyl(2-fluoroethyl)amino]phenyl]propanoic acid serves as a prime example of how chemical modifications can lead to complex interactions in biological systems. Continued research into its mechanisms of action could reveal valuable insights into new pharmacotherapies.

Synonyms
NSC 84320
BRN 2860971
4235-44-3
HYDROCINNAMIC ACID, p-((2-CHLOROETHYL)(2-FLUOROETHYL)AMINO)-
p-((2-Chloroethyl)(2-fluoroethyl)amino)hydrocinnamic acid
DTXSID60195163
DTXCID70117654
NSC84320
NSC-84320