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Meclozine

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Identification
Molecular formula
C25H27ClN2OS
CAS number
569-65-3
IUPAC name
3-[4-[3-(2-chloro-9H-thioxanthen-9-yl)propyl]piperazin-1-yl]propan-1-ol
State
State

At room temperature, meclozine is typically found in a solid state. As a pharmaceutical substance, it is often formulated into oral dosage forms, such as tablets or capsules, which are distributed in blister packs or bottles.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
293.60
Boiling point (Kelvin)
566.80
General information
Molecular weight
390.95g/mol
Molar mass
390.9510g/mol
Density
1.1100g/cm3
Appearence

Meclozine, commonly known as meclizine, is typically a white to slightly yellow crystalline powder. It is practically odorless and may have a slightly bitter taste. In pharmaceutical formulations, it may appear as tablets or capsules, often in combination with other excipients.

Comment on solubility

Solubility of 3-[4-[3-(2-chloro-9H-thioxanthen-9-yl)propyl]piperazin-1-yl]propan-1-ol

The solubility of 3-[4-[3-(2-chloro-9H-thioxanthen-9-yl)propyl]piperazin-1-yl]propan-1-ol in various solvents can be quite fascinating due to its complex structure. Here are some important points regarding its solubility:

  • Polarity: The compound contains both polar and non-polar functional groups, which can influence its solubility in different mediums.
  • Solvent Compatibility: It is likely to be more soluble in polar solvents such as water or alcohols, compared to non-polar solvents like hexane.
  • Temperature Dependance: Solubility can significantly change with temperature; increased temperatures often enhance solubility in most cases.
  • pH Influence: The solubility may also be affected by the pH of the solution, particularly due to the presence of the piperazine moiety, which can interact with acids or bases.

As a general guideline, one might say, “Always consult detailed solubility data for specific usage,” as solubility can vary widely based on experimental conditions. Understanding the solubility profile is crucial for applications in drug formulation and chemical synthesis.


Interesting facts

Interesting Facts about 3-[4-[3-(2-chloro-9H-thioxanthen-9-yl)propyl]piperazin-1-yl]propan-1-ol

This compound is a fascinating example of how complex organic structures can be designed to interact with biological systems. It features a unique combination of a thioxanthene moiety and a piperazine ring, which are integral to its potential pharmaceutical applications. Here are some interesting points about this compound:

  • Thioxanthene Derivative: The thioxanthene part of the structure is notable for its role in the development of antipsychotic medications. Thioxanthenes have shown efficacy in alleviating symptoms of schizophrenia and other psychotic disorders.
  • Piperazine Influence: The presence of the piperazine ring enhances the molecule's ability to interact with neurotransmitter receptors in the brain, potentially contributing to its therapeutic effects.
  • Chlorine Atom: The chlorine substituent on the thioxanthene contributes to the compound's lipophilicity, which may affect its distribution in biological systems and enhance its pharmacological profile.
  • Multifunctional Potential: This compound could be explored for various pharmaceutical applications, possibly influencing mood and behavior due to its neuroactive properties.
  • Research Value: As a compound designed for potential medicinal use, it may be of interest to researchers who study drug design and development, particularly in the context of mental health.

Overall, 3-[4-[3-(2-chloro-9H-thioxanthen-9-yl)propyl]piperazin-1-yl]propan-1-ol exemplifies the intricate relationship between chemical structure and biological function. Its unique architecture not only offers potential therapeutic benefits but also serves as a reminder of the creativity and complexity inherent in medicinal chemistry. As stated by notable chemist "The synthesis of new compounds is an art as much as it is a science." By understanding and manipulating such compounds, scientists can pave the way for innovative treatments for various ailments.

Synonyms
Xanthiol
14008-71-0
Xanthiol [INN]
UNII-MDW4J03B3Z
MDW4J03B3Z
xantiol
4-(3-(2-CHLORO-9H-THIOXANTHEN-9-YL)PROPYL)-1-PIPERAZINE-1-PROPANOL
xanthiolum
3-[4-[3-(2-chloro-9H-thioxanthen-9-yl)propyl]piperazin-1-yl]propan-1-ol
3-{4-[3-(2-CHLORO-9H-THIOXANTHEN-9-YL)PROPYL]PIPERAZIN-1-YL}PROPAN-1-OL
CHEMBL2110631
SCHEMBL29904769
DTXSID30930700
AKOS015856384
Q27283940