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Iodixanol

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Identification
Molecular formula
C35H44I6N6O15
CAS number
92339-11-2
IUPAC name
3-[[4-[[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)phenyl]carbamoyl]benzoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid
State
State

At room temperature, iodixanol is typically found in its solid form as a crystalline powder. However, for its use in medical diagnostics, it is dissolved in aqueous solutions to form contrast agents.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.15
Boiling point (Celsius)
330.00
Boiling point (Kelvin)
603.15
General information
Molecular weight
1550.20g/mol
Molar mass
1 550.1980g/mol
Density
1.6800g/cm3
Appearence

Iodixanol is a white crystalline powder. It is highly soluble in water, which is crucial because it is primarily used in a liquid formulation for medical imaging purposes.

Comment on solubility

Solubility of 3-[[4-[[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)phenyl]carbamoyl]benzoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid

The compound 3-[[4-[[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)phenyl]carbamoyl]benzoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid, with the chemical formula C35H44I6N6O15, exhibits notable solubility characteristics. Its complex structure includes multiple carboxylic acid groups, which can enhance solubility in polar solvents such as water, particularly under acidic or basic conditions.

Here are some important factors influencing its solubility:

  • Presence of Carboxylic Groups: The carboxylic acid functional groups can dissociate in solution, contributing to increased solubility.
  • Hydrogen Bonding: The ability to participate in hydrogen bonding can facilitate solvation in polar solvents.
  • Iodine Atoms: The presence of iodine, which has a high molecular weight and large radius, may limit solubility in some organic solvents.
  • Temperature Effect: Solubility can generally increase with higher temperatures, but the effectiveness varies depending on the solvent used.

In summary, while 3-[[4-[[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)phenyl]carbamoyl]benzoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid demonstrates reasonable solubility in polar solvents due to its polar functional groups, its overall solubility profile is nuanced and dependent on specific solvent interactions and environmental conditions.

Interesting facts

Interesting Facts about 3-[[4-[[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)phenyl]carbamoyl]benzoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid

This fascinating compound, often referred to in scientific literature due to its intricate structure and potential applications, has garnered attention for several reasons:

  • Iodinated Structure: The presence of multiple iodine atoms not only affects the compound's physical properties but also has implications in medicinal chemistry, particularly in the field of imaging and diagnostics.
  • Therapeutic Potential: Compounds with carboxylic acid and carbamoyl groups have been studied for their roles in anti-cancer therapies, offering pathways to more targeted treatment options.
  • Complex Design: The structural design includes several aromatic rings, which are crucial in drug design as they can facilitate binding interactions with biological targets.
  • Biological Activity: The diverse functionalities present in this compound suggest it may have a broad spectrum of biological activities that are worthy of exploration.

As noted by researchers in the field, "Chemical complexity often correlates with increased biological activity." This compound epitomizes that notion, enabling scientists to delve deeper into both its chemical behavior and its biological effects.

Overall, the compound is a prime example of how sophisticated chemical structures can impact both the understanding of chemistry and the development of therapeutic agents. As research continues, it is likely that more applications and insights will be uncovered.

Synonyms
BRN 2800390
13013-78-0
Isophthalamic acid, 5,5'-(1,4-phenylenebis(carbonylimino))bis(N-methyl-2,4,6-triiodo-
DTXSID50156364
5,5'-(1,4-Phenylenebis(carbonylimino))bis(N-methyl-2,4,6-triiodoisophthalamic acid)
DTXCID2078855