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DASA-58

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Identification
Molecular formula
C17H18N2O6S
CAS number
499192-71-7
IUPAC name
3-[4-[(3,4-dimethoxyphenyl)sulfonylamino]phenyl]prop-2-enehydroxamic acid
State
State

At room temperature, DASA-58 is a solid. It is usually supplied in powdered form and may be slightly hygroscopic, requiring storage in a dry environment.

Melting point (Celsius)
0.00
Melting point (Kelvin)
0.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
392.44g/mol
Molar mass
392.4370g/mol
Density
1.3000g/cm3
Appearence

DASA-58 is typically a white to off-white powder. It is a solid at room temperature and should be handled in a dry form to maintain its stability and appearance.

Comment on solubility

Solubility of 3-[4-[(3,4-dimethoxyphenyl)sulfonylamino]phenyl]prop-2-enehydroxamic acid (C17H18N2O6S)

The solubility of 3-[4-[(3,4-dimethoxyphenyl)sulfonylamino]phenyl]prop-2-enehydroxamic acid can be influenced by various factors, including its chemical structure and the presence of functional groups. Understanding its solubility is crucial for applications in pharmaceuticals and chemical research.

Key Factors Influencing Solubility:

  • Polarity: This compound features polar hydroxamic acid groups and non-polar aromatic rings, suggesting a mixed polarity that may affect its ability to dissolve in different solvents.
  • Functional Groups: The presence of sulfonamide and hydroxamic functionalities may enhance interactions with water molecules, potentially increasing solubility in aqueous environments.
  • Temperature: As with many organic compounds, increased temperature may augment solubility, allowing for a more precise understanding during experimental conditions.
  • pH: The solubility might vary with pH due to protonation or deprotonation of functional groups, making it essential to assess this during assays.

In summary, while predicting the solubility of 3-[4-[(3,4-dimethoxyphenyl)sulfonylamino]phenyl]prop-2-enehydroxamic acid requires careful consideration of its molecular characteristics, preliminary evaluations suggest that it might be moderately soluble in polar solvents such as water or alcohols, though exact solubility parameters should be experimentally determined for more accurate insights.

Interesting facts

Interesting Facts About 3-[4-[(3,4-dimethoxyphenyl)sulfonylamino]phenyl]prop-2-enehydroxamic acid

This compound, known for its complex structure, falls under the category of hydroxamic acids, which are notable in various chemical and biochemical applications. Here are some intriguing aspects:

  • Biological Significance: Hydroxamic acids, including this compound, are known to exhibit a wide range of biological activities. They are often investigated for their potential as anti-cancer agents and are known to inhibit metalloproteinases, which play a crucial role in tissue remodeling and cancer metastasis.
  • Structure and Function: The presence of the sulfonylamino group in this compound enhances its reactivity and bioactivity. This modification allows for better interactions with biological targets.
  • Synthetic Interest: The synthesis of this compound can involve multiple steps, utilizing various reaction conditions and reagents. Such complexity is what often draws chemists to explore novel synthetic pathways to improve yield and sustainability.
  • Structure-Activity Relationship (SAR): Scientists are keen on studying the SAR of hydroxamic acids like this one. This analysis helps in understanding how changes in chemical structure affect their biological activity, guiding the design of new and more effective compounds.

As noted by researchers, "the intricate balance of structure and function in hydroxamic acids highlights their potential in therapeutic applications." The exploration of this compound exemplifies how modifications in small molecules can lead to significant advancements in medicinal chemistry.

Moreover, this compound exemplifies the diversity found in organic chemistry, showcasing how variations in functional groups can lead to entirely different properties and uses in scientific research.

Synonyms
PD081532