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Tranexamic acid hydrochloride

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Identification
Molecular formula
C16H25ClN2O4
CAS number
701-54-2
IUPAC name
3-[4-[4-(aminomethyl)cyclohexanecarbonyl]oxyphenyl]propanoic acid;hydrochloride
State
State

At room temperature, tranexamic acid hydrochloride is typically found in a solid state, particularly as a crystalline powder.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.15
Boiling point (Celsius)
766.90
Boiling point (Kelvin)
1 040.00
General information
Molecular weight
339.82g/mol
Molar mass
339.8230g/mol
Density
1.4408g/cm3
Appearence

Tranexamic acid hydrochloride is a white crystalline powder. It is odorless, or may have a very slight specific odor. The powder is hygroscopic and soluble in water.

Comment on solubility

Solubility of 3-[4-[4-(aminomethyl)cyclohexanecarbonyl]oxyphenyl]propanoic acid; hydrochloride

The solubility of 3-[4-[4-(aminomethyl)cyclohexanecarbonyl]oxyphenyl]propanoic acid; hydrochloride is crucial for its potential applications in various fields, especially in pharmaceuticals. This compound exhibits characteristics that can influence its solubility:

  • Ionic Nature: Being a hydrochloride salt, it is likely soluble in polar solvents such as water due to the presence of charged functional groups.
  • pH Dependence: The solubility may vary with pH, as acids and bases can release or accept protons, thus altering the ionization state.
  • Hydrogen Bonding: The amine and carboxylic acid functional groups can engage in hydrogen bonding with water, enhancing solubility.
  • Molecular Size: The relatively large and complex structure may hinder solubility to some extent, particularly in lipophilic solvents.

In summary, while the ionic and polar properties suggest that 3-[4-[4-(aminomethyl)cyclohexanecarbonyl]oxyphenyl]propanoic acid; hydrochloride may have good solubility in water, specific conditions such as temperature, solvent nature, and pH must be considered to fully understand its solubility profile. As always, empirical testing is essential to confirm theoretical predictions!

Interesting facts

Interesting Facts about 3-[4-[4-(Aminomethyl)cyclohexanecarbonyl]oxyphenyl]propanoic Acid; Hydrochloride

This compound, often referred to in scientific contexts as a derivative of amino acids, possesses several intriguing characteristics that highlight its significance in organic chemistry and pharmaceuticals. Below are some noteworthy points:

  • Biological Relevance: The compound is known for its role in modulating neurotransmitter systems. It can be a crucial building block in developing medications targeting conditions such as anxiety and depression.
  • Structural Complexity: Its multi-functional structure allows for various chemical reactions, making it a versatile candidate for further modifications in medicinal chemistry.
  • Solvent Interactions: The presence of both polar and non-polar groups within its structure enhances its ability to interact with different solvent systems, which can improve bioavailability when utilized in drug formulations.
  • Potential Applications: Researchers have shown interest in this compound for applications beyond pharmaceuticals, including its use in materials science and bioconjugation techniques.
  • Historical Significance: Similar compounds have shaped the development of numerous therapeutic agents, paving the way for innovative treatments in modern medicine.

As highlighted by scientists exploring the potential of similar compounds, "A single modification can result in a molecule with vastly different biological activity." This underscores the importance of continuous research in the field of organic synthesis and medicinal chemistry.

Whether it is enhancing efficacy or reducing side effects, the study of such compounds can lead to breakthroughs that significantly impact health and science. The exploration of 3-[4-[4-(Aminomethyl)cyclohexanecarbonyl]oxyphenyl]propanoic acid; hydrochloride serves as a prime example of the intricate dance between chemistry and biological systems.

Synonyms
cetraxate hydrochloride
27724-96-5
Cetraxate, Hydrochloride
CETRAXATE HCl
Neuer
DV-1006
Cetraxate (hydrochloride)
DV1006
MFCD01722166
08IT6P8VHY
4'-(2-Carboxyethyl)phenyl-trans-4-aminomethylcyclohexane carboxylate hydrochloride
DTXSID3046459
Benzenepropanoic acid, 4-(((4-(aminomethyl)cyclohexyl)carbonyl)oxy)-, hydrochloride, trans-
p-Hydroxyhydrocinnamic acid trans-4-(aminomethyl)cyclohexanecarboxylate, hydrochloride
27724-96-5 (HCl)
3-[4-[4-(aminomethyl)cyclohexanecarbonyl]oxyphenyl]propanoic acid;hydrochloride
DTXCID1026459
MLS001401399
3-{4-[4-(aminomethyl)cyclohexanecarbonyloxy]phenyl}propanoic acid hydrochloride
Cetraxato clorhidrato
CAS-27724-96-5
Cetraxato clorhidrato [Spanish]
NCGC00164584-01
Cetraxate hydrochloride [USAN:JAN]
SMR000469197
UNII-08IT6P8VHY
DV 1006
Neuer (TN)
4-(2-carboxyethyl)phenyl-trans-4-aminomethylcyclohexane carboxylate hydrochloride
SCHEMBL144285
SCHEMBL144286
CHEMBL502896
orb1306890
USROQQUKEBHOFF-UHFFFAOYSA-N
CETRAXATE HYDROCHLORIDE [MI]
Tox21_112210
CETRAXATE HYDROCHLORIDE [JAN]
MFCD16039388
CETRAXATE HYDROCHLORIDE [USAN]
AKOS025311449
AKOS030239788
Cetraxate hydrochloride (JP17/USAN)
Tox21_112210_1
CCG-100854
CETRAXATE HYDROCHLORIDE [MART.]
FC64977
NC00104
CETRAXATE HYDROCHLORIDE [WHO-DD]
Hydrocinnamic acid, p-hydroxy-, 4-(aminomethyl)cyclohexanecarboxylate hydrochloride, trans-
NCGC00164584-03
AS-58253
SY234513
DB-047265
HY-122762
C3454
CS-0088850
NS00028358
D02266
T70707
Q27236401
3-[4-[[trans-4-(Aminomethyl)cyclohexyl]carbonyloxy]phenyl]propanoic Acid Hydrochloride