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Pramipexole dihydrochloride

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Identification
Molecular formula
C16H25Cl2N3S
CAS number
104632-26-0
IUPAC name
3-[4-(9,9-dimethyl-3-aza-9-azoniabicyclo[3.3.1]nonan-3-yl)butyl]-9,9-dimethyl-3-aza-9-azoniabicyclo[3.3.1]nonane;diiodide
State
State

Pramipexole dihydrochloride is a solid at room temperature. It is stable under normal conditions and does not exhibit any significant vapor pressure at room temperature, making it convenient for storage and handling.

Melting point (Celsius)
296.00
Melting point (Kelvin)
569.00
Boiling point (Celsius)
360.00
Boiling point (Kelvin)
633.00
General information
Molecular weight
302.42g/mol
Molar mass
302.4220g/mol
Density
1.6400g/cm3
Appearence

Pramipexole dihydrochloride appears as a white or off-white crystalline powder. It is typically available in the form of tablets for medical use. The compound is soluble in water, forming a clear solution.

Comment on solubility

Solubility of 3-[4-(9,9-dimethyl-3-aza-9-azoniabicyclo[3.3.1]nonan-3-yl)butyl]-9,9-dimethyl-3-aza-9-azoniabicyclo[3.3.1]nonane;diiodide

The compound 3-[4-(9,9-dimethyl-3-aza-9-azoniabicyclo[3.3.1]nonan-3-yl)butyl]-9,9-dimethyl-3-aza-9-azoniabicyclo[3.3.1]nonane;diiodide is an interesting example of quaternary ammonium salts, which typically exhibit unique solubility characteristics due to their ionic nature.

In general, solubility is influenced by factors such as:

  • Ionic strength: As a diiodide, this compound dissociates in solution, enhancing its interactions with polar solvents.
  • Polarity: The presence of multiple polar functional groups in the structure may contribute to its solubility in water and other polar solvents.
  • Hydrogen bonding: The ability to form hydrogen bonds can often improve the solubility profile, particularly in aqueous environments.

Considering these aspects, it can be expected that:

  • The diiodide counterpart generally increases the solubility of the compound in polar solvents.
  • Hydrophilic interactions will facilitate its dissolution in water and other protic solvents.
  • However, solubility in non-polar solvents is likely to be low due to the ionic nature of the compound.

As a result, it is safe to say that "the more polar the solvent, the better the solubility." This characteristic makes such compounds particularly useful in various applications, including medicinal chemistry and materials science.

Interesting facts

Interesting Facts about 3-[4-(9,9-Dimethyl-3-aza-9-azoniabicyclo[3.3.1]nonan-3-yl)butyl]-9,9-dimethyl-3-aza-9-azoniabicyclo[3.3.1]nonane; Diiodide

This fascinating compound is an interesting example of quaternary ammonium compounds, particularly due to its complex structure and multiple functional groups. Here are some key highlights:

  • Unique Structure: The compound features a bicyclic structure that includes both the aza (nitrogen-containing) and quaternary ammonium functionalities. This arrangement renders it highly versatile for various applications, especially in organic synthesis and medicinal chemistry.
  • Potential Applications: Compounds like this one have shown promise in areas such as:
    • Antimicrobial agents
    • Drug delivery systems
    • Cationic surfactants
  • Biological Activity: The presence of the nitrogen atoms contributes to the compound's potential biological activity. Studies have indicated that similar quaternary ammonium salts may exhibit interesting pharmacological effects, making this molecule a subject of interest in drug discovery.
  • Salt Formation: The diiodide form of this molecule highlights the relevance of ionic interactions in stabilizing the compound and enhancing its solubility in polar solvents, which is key for its functionality in biological systems.
  • Synthesis Challenges: The synthesis of such complex molecules often poses challenges due to issues like regioselectivity and stereoselectivity. Scientists must employ creative synthetic strategies to navigate these hurdles effectively.

Overall, 3-[4-(9,9-Dimethyl-3-aza-9-azoniabicyclo[3.3.1]nonan-3-yl)butyl]-9,9-dimethyl-3-aza-9-azoniabicyclo[3.3.1]nonane; diiodide serves as a remarkable illustration of how intricate molecular design can offer insights into new compounds with significant potential in both research and application.

Synonyms
Nobutan
Nobutane
OF 1478
3406-44-8
1,4-Bis(9-methyl-3,9-diazabicyclo(3,3,1)nonane-3)-butane dimethiodide
3,3'-Tetramethylenebis(9,9-dimethyl-3-aza-9-azoniabicyclo(3.3.1)nonane) diiodide
3-Aza-9-azoniabicyclo(3.3.1)nonane, 3,3'-tetramethylenebis(9,9-dimethyl-, diiodide
DTXSID30955615
3,3'-(Butane-1,4-diyl)bis(9,9-dimethyl-3,9-diazabicyclo[3.3.1]nonan-9-ium) diiodide