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3-(4-acetylphenyl)-5-(prop-2-ynoxymethyl)oxazolidin-2-one

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Identification
Molecular formula
C15H15NO4
CAS number
132467-95-7
IUPAC name
3-(4-acetylphenyl)-5-(prop-2-ynoxymethyl)oxazolidin-2-one
State
State

At room temperature, 3-(4-acetylphenyl)-5-(prop-2-ynoxymethyl)oxazolidin-2-one is typically found as a solid.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.00
Boiling point (Celsius)
525.50
Boiling point (Kelvin)
798.60
General information
Molecular weight
261.28g/mol
Molar mass
261.2800g/mol
Density
1.2400g/cm3
Appearence

The compound typically appears as a crystalline solid. It may form colorless to off-white crystals or powder, depending on purity and hydration state.

Comment on solubility

Solubility of 3-(4-acetylphenyl)-5-(prop-2-ynoxymethyl)oxazolidin-2-one

The solubility of 3-(4-acetylphenyl)-5-(prop-2-ynoxymethyl)oxazolidin-2-one is influenced by its unique chemical structure and functional groups. Understanding its solubility profile is crucial for applications in pharmaceuticals and materials science.

Key factors affecting solubility:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents such as water.
  • Hydrogen bonding: This compound may engage in hydrogen bonding, increasing its solubility in certain solvents.
  • Temperature: Solubility often increases with temperature, which can facilitate the dissolution process.
  • pH levels: The compound’s solubility can vary with changes in pH, especially if it contains acidic or basic sites.

In practical terms:

  • It is essential to consider solvent selection; for example, polar aprotic solvents might be favorable for achieving higher solubility.
  • In synthesis and formulation, optimizing concentration and environmental conditions is key to effective utilization.

As a reminder, always consult experimental data to ascertain specific solubility thresholds and behavior in different environments, as theoretical predictions may not always align with practical outcomes.

Interesting facts

Fascinating Insights into 3-(4-acetylphenyl)-5-(prop-2-ynoxymethyl)oxazolidin-2-one

This compound is a member of the oxazolidinone class, which has garnered significant attention for its diverse applications in medicinal chemistry. Here are some intriguing aspects of this compound:

  • Medicinal Significance: Oxazolidinones have been extensively studied for their antibacterial properties, particularly against resistant strains of bacteria. This compound's unique substituents could enhance its antimicrobial activity.
  • Versatile Structure: The structure combines multiple functional groups, including an acetyl group and an alkyne, which may confer unique electronic and steric properties. This versatility often leads to unexpected biological activities.
  • Synthetic Pathways: The synthesis of oxazolidinones can be achieved through various methods, including cyclization reactions. This compound's route to form could provide pathways for creating even more complex molecules.
  • Application in Drug Development: As research in drug design evolves, compounds like this one are crucial for developing new pharmaceuticals, particularly for conditions where existing treatments fail.
  • Research Opportunities: The presence of the prop-2-ynoxymethyl group opens avenues for further investigation—potentially leading to the development of new derivatives or forms that may exhibit improved efficacy.

In conclusion, 3-(4-acetylphenyl)-5-(prop-2-ynoxymethyl)oxazolidin-2-one is a compelling compound that exemplifies the intersection of organic synthesis and medicinal application. Its unique properties could pave the way for breakthroughs in pharmaceutical chemistry!

Synonyms
23598-69-8
BRN 0558307
2-Oxazolidinone, 3-(4-acetylphenyl)-5-(2-propynyloxymethyl)-
ACETOPHENONE, 4'-(2-OXO-5-(2-PROPYNYLOXYMETHYL)-3-OXAZOLIDINYL)-
RefChem:316948
DTXSID00946414
3-(4-Acetylphenyl)-5-{[(prop-2-yn-1-yl)oxy]methyl}-1,3-oxazolidin-2-one