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3-(4-aminophenyl)sulfonyl-1,3-diphenyl-propan-1-one

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Identification
Molecular formula
C21H19NO3S
CAS number
.123456-78-9
IUPAC name
3-(4-aminophenyl)sulfonyl-1,3-diphenyl-propan-1-one
State
State

At room temperature, the compound exists in a solid state. It demonstrates typical properties of an organic crystalline solid, being relatively stable under ambient conditions and requiring higher temperatures to transition to a liquid or gaseous state.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.20
Boiling point (Celsius)
485.20
Boiling point (Kelvin)
758.30
General information
Molecular weight
375.45g/mol
Molar mass
375.4480g/mol
Density
1.3000g/cm3
Appearence

The compound typically appears as a crystalline solid. The crystals can range from colorless to light yellow, depending on impurities and the method of synthesis. The compound may be presented in powder form for laboratory and industrial purposes.

Comment on solubility

Solubility of 3-(4-aminophenyl)sulfonyl-1,3-diphenyl-propan-1-one

The solubility of 3-(4-aminophenyl)sulfonyl-1,3-diphenyl-propan-1-one presents some intriguing characteristics, influenced by its molecular structure and functional groups. Generally, the solubility of such compounds can vary based on several factors:

  • Polarity: The presence of the sulfonyl (-SO₂-) and amino (-NH₂) groups contribute to the polarity of the molecule, potentially enhancing solubility in polar solvents.
  • Hydrogen Bonding: The amino group may facilitate hydrogen bonding with water, increasing solubility compared to non-polar compounds.
  • Solvent Interaction: Its solubility may be greater in solvents such as methanol or ethanol, which can stabilize the polar functional groups.

However, due to its large aromatic hydrocarbon structure, the compound may exhibit limited solubility in non-polar solvents such as hexane or benzene. This is attributed to the hydrophobic character of the diphenyl groups, which can lead to poor solubility in non-polar environments.

In summary, consider the following aspects when assessing solubility:

  • **Higher solubility in polar solvents** due to polar functional groups.
  • **Potential aggregation** in non-polar solvents due to hydrophobic interactions.

Overall, while the compound demonstrates some degree of polarity that may enhance its solubility in appropriate solvents, further investigation is needed to quantify its solubility in various environments.

Interesting facts

Interesting Facts about 3-(4-Aminophenyl)sulfonyl-1,3-diphenyl-propan-1-one

3-(4-Aminophenyl)sulfonyl-1,3-diphenyl-propan-1-one, often referred to for its multifaceted properties, plays a significant role in different fields of chemistry and medicine. Here are some intriguing aspects of this compound:

  • Pharmaceutical Applications: This compound is often investigated for its potential use as a therapeutic agent, particularly in the treatment of various cancers. Its unique structure allows it to interact with biological targets effectively, making it a candidate for drug development.
  • Versatile Structure: The presence of both an amino group and a sulfonyl moiety is responsible for its diverse reactivity. These functionalities contribute to its ability to form various derivatives, further enhancing its medicinal potential.
  • Colorimetric Reactions: Due to its distinct functional groups, this compound can participate in specific chemical reactions that yield color changes. This property is particularly useful for analytical chemistry where visual indicators are required.
  • Biological Significance: Studies have shown that compounds with similar structures often exhibit antioxidant properties, which can protect cells from oxidative stress and contribute to overall health.

In summary, 3-(4-Aminophenyl)sulfonyl-1,3-diphenyl-propan-1-one represents a fascinating subject for ongoing research. Its physicochemical properties and biological activities make it an essential compound in both synthetic and medicinal chemistry. As stated by renowned chemists, “The beauty of a compound lies in its ability to transform within various contexts,” making this compound a prime example of such versatility.

Synonyms
ALKOFANONE
7527-94-8
alfone
UNII-96JNQ0UCWD
96JNQ0UCWD
ALKOFANONE [MI]
1-Propanone, 3-((4-aminophenyl)sulfonyl)-1,3-diphenyl-
3-((4-AMINOPHENYL)SULFONYL)-1,3-DIPHENYL-1-PROPANONE
1-Propanone, 3-((4-aminophenyl)sulfonyl)-1,3-diphenyl-(9CI)
(+-)-3-((4-AMINOPHENYL)SULFONYL)-1,3-DIPHENYL-1-PROPANONE
3-(4-aminophenyl)sulfonyl-1,3-diphenylpropan-1-one
SCHEMBL667296
DTXSID40996736
CHEBI:135540
AKOS040750323
Q27271905
3-(4-Aminobenzene-1-sulfonyl)-1,3-diphenylpropan-1-one
(+/-)-3-((4-AMINOPHENYL)SULFONYL)-1,3-DIPHENYL-1-PROPANONE