Interesting facts
Interesting Facts about 3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic Acid
3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid is a fascinating chemical compound primarily known for its role in medicinal chemistry and anti-cancer research. Here are some engaging insights about this compound:
- Cancer Treatment: This compound is part of a class of agents that have shown potential in targeting cancer cells. Its structure allows it to interact effectively with biological systems, which is crucial for developing new cancer therapies.
- Mechanism of Action: The remarkable bis(2-chloroethyl)amino moiety has alkylating properties, enabling it to form covalent bonds with DNA, thereby disrupting the replication process of rapidly dividing cancer cells.
- Structure-Activity Relationship: The design of this compound emphasizes the significance of functional groups in enhancing pharmacological activity. Small modifications can lead to substantial changes in its efficacy against various cancer types.
- Historical Context: Compounds with similar structures were developed during the mid-20th century and have inspired a plethora of derivatives to broaden the scope of cancer treatment options.
- Toxicity Considerations: While its potential is promising, the cytotoxic nature of such compounds necessitates careful consideration of dosage to minimize adverse effects on healthy cells.
Overall, 3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid serves as a pivotal example of how organic chemistry can contribute to advancements in pharmaceutical applications. As research continues, its legacy in the fight against cancer may evolve, offering hope for innovative treatment solutions.
Synonyms
Norchlorambucil
6746-11-8
3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid
p-di(2-Chloropropyl)aminophenylpropionic acid
NSC 71965
EQ76NQE8XD
4-Bis(2-chloroethyl)aminobenzenepropanoic acid
NSC-71965
HYDROCINNAMIC ACID, p-(BIS(2-CHLOROETHYL)AMINO)-
Benzenepropanoic acid, 4-(bis(2-chloroethyl)amino)-
Hydrocinnamic acid, p-[bis(2-chloroethyl)amino]-
3-(4-(Bis(2-chloroethyl)amino)phenyl)propanoic acid
Benzenepropanoic acid, 4-[bis(2-chloroethyl)amino]-
CB 1332
BRN 3059603
UNII-EQ76NQE8XD
p-(Bis(2-chloroethyl)amino)hydrocinnamic acid
NCIOpen2_003781
p-N,N-Di-(2-chloroethyl)aminophenylpropionic acid
3-(p-(Bis(2-chloroethyl)amino)phenyl)propionic acid
SCHEMBL2564390
CHEMBL3247490
DTXSID60217793
CXUFBRINAAJGEB-UHFFFAOYSA-N
NSC71965
AKOS003263368
p-N,N-Di(2-chloroethyl)aminophenylpropionic acid
4-14-00-01532 (Beilstein Handbook Reference)
BIS(2-CHLOROETHYL)AMINOBENZENEPROPANOIC ACID, 4-
3-[4-(N,N-bis(2-chloroethyl)amino)phenyl]propanoic acid
3-[4-[N,N-Bis(2-chloroethyl)amino]phenyl]propionic acid
Solubility of 3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid
The solubility of the compound 3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid is a subject of interest due to its unique structural characteristics. This compound is generally considered to have varied solubility properties depending on the solvent used.
Key considerations for solubility include:
However, it is essential to note that while 3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid can dissolve in certain polar solvents, its solubility may be markedly reduced in nonpolar solvents due to hydrophobic interactions. In practice, it is advisable to conduct experimental solubility tests for precise information, as the interactions can be influenced by the compound’s purity and the presence of other solutes.
In conclusion, the solubility of this compound is influenced by multiple factors and may vary significantly across different environments.