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Flufenamic acid

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Identification
Molecular formula
C15H12F2NO2
CAS number
530-78-9
IUPAC name
3-[4-[bis(2-fluoroethyl)amino]phenyl]prop-2-enoic acid
State
State

At room temperature, flufenamic acid is in a solid state. It is typically found in a stable crystalline form under standard laboratory conditions.

Melting point (Celsius)
134.50
Melting point (Kelvin)
407.70
Boiling point (Celsius)
488.60
Boiling point (Kelvin)
761.80
General information
Molecular weight
281.25g/mol
Molar mass
281.2540g/mol
Density
1.3090g/cm3
Appearence

Flufenamic acid typically appears as a white to faintly yellow crystalline powder. It is often provided in its solid crystalline form for medical and research purposes. The crystals are typically odorless.

Comment on solubility

Solubility of 3-[4-[bis(2-fluoroethyl)amino]phenyl]prop-2-enoic acid

The solubility of 3-[4-[bis(2-fluoroethyl)amino]phenyl]prop-2-enoic acid can be influenced by several factors, which play a crucial role in its applicability in various chemical processes.

  • Polarity: This compound contains polar functional groups, including an amine and a carboxylic acid. The presence of these groups generally enhances its ability to dissolve in polar solvents.
  • Hydrogen bonding: The carboxylic acid group can engage in hydrogen bonding, potentially increasing solubility in water. As noted, "Hydrogen bonds can significantly impact the dissolution process."
  • Solvent choice: To optimize solubility, considering solvents such as dimethyl sulfoxide (DMSO) or ethanol may be advantageous. Each solvent interacts differently with the molecular structure.
  • Temperature: Increasing the temperature often improves solubility, particularly for organic compounds; however, this may vary with this specific acid.

It is essential to conduct empirical studies to determine the exact solubility characteristics of this compound, as interactions in complex mixtures can have unforeseen effects. Solubility data provides valuable insights into material behavior and its suitability for applications in medicinal chemistry and materials science.

Interesting facts

Exploring 3-[4-[bis(2-fluoroethyl)amino]phenyl]prop-2-enoic acid

This fascinating compound, known for its unique structure and properties, offers a glimpse into the complexities of organic chemistry. Below are some intriguing aspects of 3-[4-[bis(2-fluoroethyl)amino]phenyl]prop-2-enoic acid:

  • Structural Significance: The compound showcases a distinctive prop-2-enoic acid backbone that is functionalized with a bis(2-fluoroethyl)amino group. This structure imparts notable properties that can be explored further through synthetic chemistry.
  • Fluorinated Chemistry: Fluoroethyl groups are often included for their ability to modify the chemical and biological behavior of organic molecules. The presence of fluorine can enhance lipid solubility and influence pharmacokinetics, making this compound of interest in medicinal chemistry.
  • Potential Applications: Due to its structural characteristics, this compound may be investigated for use in drug design or as a building block in the synthesis of more complex molecules. Its unique properties can provide insights into how modifications can lead to changes in reactivity and functional behavior.
  • Research Opportunities: The study of compounds like 3-[4-[bis(2-fluoroethyl)amino]phenyl]prop-2-enoic acid can pave the way for understanding better organic reactions and the development of new materials or pharmaceuticals.
  • Interdisciplinary Interest: The compound traverses various disciplines including materials science, pharmacology, and biochemistry, making it a cross-sectional point for researchers from diverse fields to collaborate and innovate.

This compound not only provides a rich topic for academic exploration, but it also emphasizes the importance of interdisciplinary studies in advancing the field of chemistry. The interrelationships between molecular structures and their properties can lead to groundbreaking developments in science and technology.

Synonyms
NCIOpen2_004572