Skip to main content

Fluoxetine

ADVERTISEMENT
Identification
Molecular formula
C13H16F3NO2
CAS number
54910-89-3
IUPAC name
3-[4-[bis(2-fluoroethyl)amino]phenyl]propanoic acid
State
State

At room temperature, Fluoxetine is found in a solid state. It is stable under normal conditions but should be stored in a tightly sealed container to prevent moisture absorption.

Melting point (Celsius)
179.00
Melting point (Kelvin)
452.15
Boiling point (Celsius)
281.00
Boiling point (Kelvin)
554.15
General information
Molecular weight
315.34g/mol
Molar mass
315.3400g/mol
Density
1.2700g/cm3
Appearence

Fluoxetine is typically found as a white to off-white crystalline solid, which may appear as a powder due to its crystal formation. It is known to be hygroscopic, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of 3-[4-[bis(2-fluoroethyl)amino]phenyl]propanoic acid

The solubility of 3-[4-[bis(2-fluoroethyl)amino]phenyl]propanoic acid is influenced by several factors, making it a topic of interest in various chemical applications. Understanding its solubility characteristics can help predict its behavior in different environments.

Key Points on Solubility:

  • Polar vs. Non-Polar Solvent: The compound exhibits varying solubility in polar and non-polar solvents. Due to the presence of the carboxylic acid group, it tends to be more soluble in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules significantly enhances its solubility.
  • Functional Groups: The bis(2-fluoroethyl)amino group introduces interesting interactions that can affect solubility. This might lead to increased solubility in organic solvents as compared to water.
  • Temperature Effects: Like many organic acids, its solubility may increase with temperature, showcasing typical behavior of solubility dynamics.

In conclusion, while the solubility of 3-[4-[bis(2-fluoroethyl)amino]phenyl]propanoic acid can vary based on environmental conditions and solvent choice, its tendency to dissolve in polar solvents is notable due to its functional groups and potential for hydrogen bonding. Understanding these nuances can provide essential insights for practical applications in chemical synthesis and formulation.

Interesting facts

Interesting Facts about 3-[4-[bis(2-fluoroethyl)amino]phenyl]propanoic acid

3-[4-[bis(2-fluoroethyl)amino]phenyl]propanoic acid is a fascinating compound with various implications in the field of medicinal chemistry and pharmacology. Here are some noteworthy details about this intriguing molecule:

  • Pharmaceutical Significance: This compound has garnered attention for its potential use in drug design, especially in targeting specific pathways associated with diseases such as cancer and autoimmune disorders.
  • Structural Insights: The presence of the bis(2-fluoroethyl) group enhances the lipophilicity of the molecule, potentially improving its ability to cross biological membranes. This structural modification can greatly influence its pharmacokinetic properties.
  • Mechanism of Action: Compounds like 3-[4-[bis(2-fluoroethyl)amino]phenyl]propanoic acid may interact with various receptors or enzymes, providing a rich avenue for research into how they can modulate biological processes.
  • Research Potential: Ongoing studies may reveal additional therapeutic targets for this compound, making it a promising candidate for development in drug discovery programs.
  • Environmental Considerations: The introduction of fluorine in organic compounds raises questions regarding environmental impact and persistence. This aspect opens discussions about the sustainability of using fluorinated compounds in industry.

In summary, 3-[4-[bis(2-fluoroethyl)amino]phenyl]propanoic acid showcases the intersection of chemistry and medicine, highlighting how small alterations in chemical structure can significantly impact biological activity. The ongoing research around such compounds continues to inspire innovation and discovery in the scientific community.

Synonyms
4093-12-3
HYDROCINNAMIC ACID, p-(BIS(2-FLUOROETHYL)AMINO)-
NSC 83298
BRN 2944399
p-(Bis(2-fluoroethyl)amino)hydrocinnamic acid
DTXSID70193933
Hydrocinnamic acid, p-[bis(2-fluoroethyl)amino]-
DTXCID10116424
3-[4-[bis(2-fluoroethyl)amino]phenyl]propanoic acid
NSC-83298
3-[4-(BIS(2-FLUOROETHYL)AMINO)PHENYL]PROPANOIC ACID
NSC83298
LN6RZ8HHZ9
NCIOpen2_004789
4-[Bis(2-fluoroethyl)amino]benzenepropanoic acid
Benzenepropanoic acid, 4-[bis(2-fluoroethyl)amino]-