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3-(4-Bromophenyl)azetidine

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Identification
Molecular formula
C9H10BrN
CAS number
115029-20-4
IUPAC name
3-(4-bromophenyl)azetidine
State
State

At room temperature, 3-(4-Bromophenyl)azetidine is typically in a solid state if pure but may be encountered as a liquid in some cases due to impurities or handling conditions.

Melting point (Celsius)
50.00
Melting point (Kelvin)
323.15
Boiling point (Celsius)
360.00
Boiling point (Kelvin)
633.15
General information
Molecular weight
212.09g/mol
Molar mass
212.0720g/mol
Density
1.4642g/cm3
Appearence

This compound is typically a colorless or pale yellow liquid. It may also appear as a crystalline solid depending on purity and environmental conditions.

Comment on solubility

Solubility of 3-(4-bromophenyl)azetidine

The solubility of 3-(4-bromophenyl)azetidine in various solvents can be affected by several factors, including its molecular structure and the nature of the solvent used. Here are some key points to consider:

  • Polarity: 3-(4-bromophenyl)azetidine contains both the azetidine ring, which is generally hydrophobic, and a bromophenyl substituent that can introduce some polar characteristics.
  • Solvent Compatibility: This compound is expected to be more soluble in non-polar solvents such as hexane or chloroform, compared to polar solvents like water.
  • Hydrogen Bonding: The potential for hydrogen bonding with certain protic solvents may affect its solubility, albeit minimally due to the lack of highly polar functional groups in its structure.
  • Concentration and Temperature: Like many organic compounds, the solubility of 3-(4-bromophenyl)azetidine can increase with temperature and concentration adjustments.

In conclusion, while specific solubility data for 3-(4-bromophenyl)azetidine may be limited, it generally demonstrates a tendency to dissolve better in non-polar solvents. Understanding the interplay of structural elements and solvent characteristics is essential for predicting the solubility behavior of this compound.

Interesting facts

Interesting Facts About 3-(4-Bromophenyl)azetidine

3-(4-Bromophenyl)azetidine is a fascinating chemical compound that belongs to the class of azetidines, which are four-membered heterocyclic compounds containing nitrogen. Here are some intriguing aspects of this compound:

  • Structural Significance: The presence of the bromophenyl group at the 3-position of the azetidine ring enhances its aromatic character and can significantly impact its reactivity and stability.
  • Pharmaceutical Relevance: Compounds similar to 3-(4-bromophenyl)azetidine are of keen interest in medicinal chemistry due to their potential as drug candidates. The azetidine ring structure can be found in various pharmacologically active compounds.
  • Reactivity: The unique structure allows for a range of chemical reactions, including nucleophilic substitutions and cycloadditions, which are invaluable in synthetic organic chemistry.
  • Applications: Research into azetidine derivatives has revealed applications in designing novel materials, pesticides, and biologically active compounds, contributing to advancements in various fields such as agriculture and medicine.
  • Research Insights: According to scientific literature, “exploring the derivatives of azetidine could lead to discovering new therapeutic agents” which highlights the potential this compound holds.

In summary, 3-(4-bromophenyl)azetidine is not just a molecule of academic interest but also a promising candidate for further research in medicinal chemistry and material science due to its unique properties and applications. Its potential continues to be explored, making it a compound to watch in the ever-evolving landscape of chemical sciences.

Synonyms
7215-01-2
3-(p-Bromophenyl)azetidine
L 2421
AZETIDINE, 3-(p-BROMOPHENYL)-
BRN 1424810
DTXSID30222470
DTXCID30144961
5-20-06-00286 (beilstein handbook reference)
3-(4-bromophenyl)azetidine
MFCD01665286
SCHEMBL15301182
JHJFWWNFVIMSMT-UHFFFAOYSA-N
GS0564
AKOS017398266
SB51445
DA-17897
PS-19097
SY019231
CS-0058165
EN300-131404
P10199