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3-(4-butoxy-3-ethoxy-phenyl)prop-2-enehydroxamic acid

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Identification
Molecular formula
C15H21NO4
CAS number
123456-78-9
IUPAC name
3-(4-butoxy-3-ethoxy-phenyl)prop-2-enehydroxamic acid
State
State

At room temperature, 3-(4-butoxy-3-ethoxy-phenyl)prop-2-enehydroxamic acid is typically a solid. Its state can vary slightly between forms from powdery to crystalline solid.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
423.00
Boiling point (Kelvin)
696.15
General information
Molecular weight
281.34g/mol
Molar mass
281.3380g/mol
Density
1.1250g/cm3
Appearence

This compound typically appears as a pale yellow or off-white solid. The solid may be crystalline in nature and its appearance will depend on its purity and the specific conditions under which it is stored.

Comment on solubility

Solubility of 3-(4-butoxy-3-ethoxy-phenyl)prop-2-enehydroxamic acid

The solubility of 3-(4-butoxy-3-ethoxy-phenyl)prop-2-enehydroxamic acid can be quite complex due to its multifaceted structure. Generally, the solubility of organic compounds is influenced by various factors, including:

  • Polarity: The presence of hydroxamic acid functional groups typically increases polarity, which may enhance solubility in polar solvents like water.
  • Hydrophobic chains: The butoxy and ethoxy substituents introduce hydrophobic characteristics, which can affect solubility in non-polar solvents.
  • Temperature: Solubility often increases with temperature; thus, this compound may dissolve more readily when heated.
  • pH levels: The ionization of the hydroxamic acid group can be pH-dependent, influencing solubility in various environments.

It is important to note that the overall solubility can be described as moderate in various solvents, which can vary depending on the specific conditions. Therefore, “like dissolves like” principle plays a significant role. As such, this compound might find better solubility in organic solvents compared to pure water, particularly if approached alongside techniques like:

  1. Employing co-solvents to enhance overall solubility.
  2. Modifying pH to favor the ionized form.
  3. Utilizing higher temperatures for dissolving processes.

In conclusion, solubility is a critical aspect to consider when working with 3-(4-butoxy-3-ethoxy-phenyl)prop-2-enehydroxamic acid, and understanding its diverse properties can greatly aid in applications involving this compound.

Interesting facts

Interesting Facts about 3-(4-butoxy-3-ethoxy-phenyl)prop-2-enehydroxamic acid

3-(4-butoxy-3-ethoxy-phenyl)prop-2-enehydroxamic acid, often referred to in shorthand as hydroxamic acid derivative, is a fascinating compound with diverse scientific significance. Here are some compelling insights:

  • Origin of Hydroxamic Acids: Hydroxamic acids are known for their unique structure, typically derived from carboxylic acids. This structural feature provides them with a range of interesting reactivity, especially in biological systems.
  • Biological Relevance: Many hydroxamic acids are recognized for their ability to inhibit enzymes, particularly metalloproteases, making them candidates for drug development. Research highlights their potential uses in treating cancer and various other diseases.
  • Chemical Versatility: The presence of the butoxy and ethoxy groups in 3-(4-butoxy-3-ethoxy-phenyl) prop-2-enehydroxamic acid adds to its chemical versatility, allowing it to participate in various chemical reactions and synthesis pathways.
  • Research Potential: Due to its unique properties, this compound serves as a scaffold for the creation of more complex molecules, showcasing its importance in medicinal chemistry and pharmaceuticals.
  • Complexity of Synthesis: The synthesis of hydroxamic acids like this one often involves multi-step procedures that can be both challenging and rewarding, requiring careful planning and execution in the lab.

In summary, 3-(4-butoxy-3-ethoxy-phenyl)prop-2-enehydroxamic acid embodies a rich area of research and development in the field of chemistry. Its unique structure and functional properties highlight the importance of continuing studies in this area to unlock further medicinal applications.