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3-(4-butoxy-3-fluorophenyl)prop-2-enohydroxamic acid

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Identification
Molecular formula
C13H16FNO3
CAS number
not available
IUPAC name
3-(4-butoxy-3-fluoro-phenyl)prop-2-enehydroxamic acid
State
State

The compound is typically a solid under standard conditions.

Melting point (Celsius)
156.30
Melting point (Kelvin)
429.45
Boiling point (Celsius)
503.15
Boiling point (Kelvin)
776.30
General information
Molecular weight
267.28g/mol
Molar mass
267.2780g/mol
Density
1.2350g/cm3
Appearence

It is a crystalline solid that appears as a white to off-white powder.

Comment on solubility

Solubility of 3-(4-butoxy-3-fluoro-phenyl)prop-2-enehydroxamic acid

The solubility of 3-(4-butoxy-3-fluoro-phenyl)prop-2-enehydroxamic acid in various solvents provides insight into its potential applications and behavior in chemical processes. This compound, featuring a hydroxamic acid functional group, often exhibits interesting solubility characteristics.

Factors Influencing Solubility

The solubility of this compound can be influenced by several factors:

  • Polarity: The presence of hydroxamic acid introduces polar characteristics, which may enhance solubility in polar solvents such as water or methanol.
  • Hydrophobic Interactions: The butoxy group contributes hydrophobic characteristics, which can improve solubility in organic solvents like ethanol or ethyl acetate.
  • pH Levels: The ionization state of the hydroxamic acid at different pH levels will affect its solubility, with greater solubility in acidic conditions.

Solubility in Different Solvents

Based on its structural features, one might expect the following solubility behaviors:

  • Water: Possible moderate solubility due to the hydroxamic acid group.
  • Organic Solvents: Likely higher solubility in organic solvents owing to the butoxy group.
  • Acidic Solutions: Increased solubility due to protonation of the hydroxamic group.

In summary, while the solubility of 3-(4-butoxy-3-fluoro-phenyl)prop-2-enehydroxamic acid can vary significantly depending on the surrounding environment, its unique combination of polar and nonpolar characteristics provides a versatile profile for use in various applications.

Interesting facts

Interesting Facts about 3-(4-butoxy-3-fluoro-phenyl)prop-2-enehydroxamic Acid

3-(4-butoxy-3-fluoro-phenyl)prop-2-enehydroxamic acid is a fascinating compound that draws interest from both the fields of chemistry and biochemistry. Here are some intriguing aspects of this compound:

  • Functional Versatility: This compound contains a hydroxamic acid functional group, which is known for its capability to chelate metal ions. This makes it particularly interesting for applications in medicinal chemistry and pharmaceuticals.
  • Role in Drug Design: Compounds with hydroxamic acid moieties are often explored as potential inhibitors in the design of drugs targeted at various enzymes, particularly metalloproteins. Inhibiting these can have significant therapeutic implications.
  • Fluoro Substitution Effect: The presence of the fluoro group can influence the compound's reactivity and interaction with biological targets. Fluorine atoms typically enhance the metabolic stability of the compounds while also modifying the lipophilicity.
  • Synthetic Interest: The synthetic routes to developing this compound often involve intricate organic synthesis techniques, showcasing the creativity and skill of chemists in the lab. Understanding these synthetic pathways can provide vital insights into structure-activity relationships.
  • Applications in Chemistry: Beyond pharmaceuticals, this compound might have applications in agricultural chemistry, especially in the development of herbicides or pesticides, thanks to its potential bioactivity.
  • Continued Research: The ongoing research into compounds like this one illustrates the ever-evolving landscape of chemical discovery. Scientists are continually investigating new analogs to enhance efficacy and reduce toxicity.

These factors together highlight the significance of 3-(4-butoxy-3-fluoro-phenyl)prop-2-enehydroxamic acid in contemporary chemical research, offering both promise and challenges in its application.