3-(4-butoxyphenyl)prop-2-enehydroxamic acid

Identification

Molecular formula

C₁₃H₁₇NO₃

CAS number

81098-46-4

IUPAC name

3-(4-butoxyphenyl)prop-2-enehydroxamic acid

State

This compound is typically found in a solid state at room temperature. It is neither a liquid nor a gas at standard conditions, and it holds its solid state until it reaches its melting point. Proper storage ensures that it maintains its solid state, free from moisture that could affect its crystalline form.

Melting point (Celsius)

105.30

Melting point (Kelvin)

378.45

Boiling point (Celsius)

315.10

Boiling point (Kelvin)

588.25

General information

Molecular weight

237.31g/mol

Molar mass

237.3110g/mol

Density

1.1565g/cm³

Appearence

3-(4-Butoxyphenyl)prop-2-enehydroxamic acid is typically a white to off-white crystalline solid. It may appear as a powder or small crystals, exhibiting a characteristic crystalline luster. Due to its organic nature and chemical structure, it may also exhibit an oily sheen when observed under certain lighting conditions. Careful handling is advised to preserve its integrity in its solid form, especially in the presence of moisture or higher temperatures.

Comment on solubility

Solubility of 3-(4-butoxyphenyl)prop-2-enehydroxamic Acid

The solubility of 3-(4-butoxyphenyl)prop-2-enehydroxamic acid in various solvents can be quite intriguing due to its unique chemical structure. This compound exhibits specific solubility characteristics based on the following factors:

Polarity: As a hydroxamic acid, its functional groups influence its interaction with polar solvents such as water. The hydroxyl (-OH) group contributes to its potential solubility in polar environments.
Alkyl Chain: The presence of the butoxy group may decrease overall polarity, suggesting better solubility in non-polar or less polar organic solvents like ethanol or dichloromethane.
Hydrogen Bonding: The ability of the hydroxamic acid group to form hydrogen bonds can enhance its solubility in polar solvents under certain conditions.

It's essential to consider these factors when evaluating the solubility of this compound. As stated, “Solubility depends not only on the nature of the solute but also on the solvent’s characteristics.”
Therefore, experimentation is often necessary to determine the precise solubility profile in different solvents, providing insights into its practical applications in various fields, such as pharmaceuticals and materials science.

In summary, due to the compound's balance of polar and non-polar features, it is anticipated to have variable solubility that would require careful assessment based on the solvent used.

Interesting facts

Interesting Facts about 3-(4-butoxyphenyl)prop-2-enehydroxamic Acid

3-(4-butoxyphenyl)prop-2-enehydroxamic acid is a fascinating compound that belongs to the class of hydroxamic acids, which are characterized by the presence of a hydroxylamine functional group. This compound exhibits a range of properties that make it of interest in various scientific fields:

Biological Activity: Hydroxamic acids, including 3-(4-butoxyphenyl)prop-2-enehydroxamic acid, are known for their role as metal chelators. They can bind to metal ions, which can be crucial in biological systems.
Anticancer Potential: Some studies have shown that derivatives of hydroxamic acids exhibit anticancer properties by inhibiting histone deacetylases (HDACs), enzymes involved in the regulation of gene expression.
Applications in Medicinal Chemistry: Research into hydroxamic acids has led to numerous drug design applications. The structural variety available within this class allows for the development of specific inhibitors targeting various diseases.
Industrial Significance: Beyond pharmaceuticals, hydroxamic acids are also investigated for their potential use in agriculture as biopesticides or herbicides due to their ability to affect growth patterns in plants.

The unique structure of 3-(4-butoxyphenyl)prop-2-enehydroxamic acid, with its butoxy-phenyl group, provides opportunities for further exploration of its properties and potential applications. As chemists continue to investigate this compound, it may lead to new breakthroughs in both medicine and agriculture.

In the words of a famous chemist, "Chemistry is the art of problem solving, and every compound is a new puzzle waiting to be solved." 3-(4-butoxyphenyl)prop-2-enehydroxamic acid is indeed one such puzzle!