Cetirizine | Solubility of Things

Identification

Molecular formula

C₂₁H₂₅ClN₂O

CAS number

83881-51-0

IUPAC name

3-[(4-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)oxy]-N,N-dimethyl-propan-1-amine

State

At room temperature, cetirizine is a solid in the form of a crystalline powder. It is not hygroscopic and practically insoluble in water.

Melting point (Celsius)

109.00

Melting point (Kelvin)

382.15

Boiling point (Celsius)

547.80

Boiling point (Kelvin)

820.90

General information

Molecular weight

388.89g/mol

Molar mass

388.8890g/mol

Density

1.1830g/cm³

Appearence

Cetirizine is typically a white or off-white crystalline powder. It is often supplied in tablet form for oral administration, and the tablets are usually round, biconvex, and film-coated.

Comment on solubility

Solubility of 3-[(4-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)oxy]-N,N-dimethyl-propan-1-amine

The solubility of 3-[(4-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)oxy]-N,N-dimethyl-propan-1-amine is an important factor to consider when evaluating its chemical behavior and potential applications. This compound possesses a complex molecular structure, which often influences its solubility profile in various solvents.

Factors Affecting Solubility:

Polarity: The presence of polar functional groups can enhance solubility in polar solvents like water.
Steric Hindrance: The bulky cycloheptane moiety may create steric hindrance, affecting how this compound interacts with solvent molecules.
Hydrogen Bonding: Compounds that can form hydrogen bonds typically show increased solubility in polar solvents, which could apply to this chemical.
Temperature: Increased temperature often boosts solubility for many organic compounds.

In general, compounds with similar characteristics to this can exhibit varied solubility, ranging from highly soluble to poorly soluble depending on their environment and interactions with solvents. For this particular compound, it would be insightful to conduct experiments under different conditions to ascertain its solubility in key solvents.

Interesting facts

Exploring 3-[(4-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)oxy]-N,N-dimethyl-propan-1-amine

This intriguing compound belongs to a class of organic compounds that exhibit diverse functionalities. Below are some of the most notable aspects of this molecule:

Structural Complexity: The structure features a central propan-1-amine chain connected to a unique quinoline derivative. The presence of the tetrahydro-cycloheptane moiety adds significant steric hindrance, making it a fascinating subject for studying molecular interactions.
Pharmacological Potential: Compounds like this one have been of interest in medicinal chemistry due to their potential as therapeutic agents. Their unique structures can interact with biological targets such as receptors or enzymes, potentially leading to new drug discoveries.
Chirality: This compound may exhibit chirality, which is important in pharmaceutical chemistry, as different enantiomers can have vastly different biological activities. Investigating the enantiomers can help in optimizing their pharmacological effects.
Applications in Research: The compound could serve as a lead compound in the development of new drugs, particularly in the realms of neuropharmacology or anti-cancer therapies, where quinoline derivatives have shown promise.

As we explore the chemistry behind this compound, there remains much to be discovered about its properties and potential applications. Scientists are continually trying to unlock the mysteries held within complex structures, and each compound brings the possibility of groundbreaking findings.

In conclusion, 3-[(4-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)oxy]-N,N-dimethyl-propan-1-amine embodies the rich interplay between structure and function that characterizes the field of chemistry. As researchers, we remain excited about the potential that compounds like this hold in advancing science and medicine.