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Loprazolam

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Identification
Molecular formula
C24H25ClN2O
CAS number
74211-93-3
IUPAC name
3-(4-chlorophenyl)-1-[4-(m-tolyl)piperazin-1-yl]-3-phenyl-propan-1-one
State
State

At room temperature, loprazolam is generally in a solid state as it is in the form of a crystalline powder.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
455.00
Boiling point (Kelvin)
728.15
General information
Molecular weight
456.95g/mol
Molar mass
456.9530g/mol
Density
1.2303g/cm3
Appearence

Loprazolam is a crystalline solid. It typically appears as a white to pale yellow crystalline powder. The appearance might vary slightly depending on the specific polymorphic form or manufacturing process.

Comment on solubility

Solubility Overview

The compound 3-(4-chlorophenyl)-1-[4-(m-tolyl)piperazin-1-yl]-3-phenyl-propan-1-one is a complex organic molecule that exhibits unique solubility characteristics. Understanding the solubility of such compounds is crucial, especially in pharmaceutical and chemical applications.

Key Factors Influencing Solubility

Several factors influence the solubility of this compound:

  • Polarity: The presence of multiple aromatic rings and functional groups affects how well the compound interacts with polar and non-polar solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvents can enhance solubility, particularly in polar solvents.
  • Temperature: As with many organic compounds, increasing temperature often increases solubility.
  • pH Levels: The pH of the solution can impact ionization, thereby affecting solubility in water.

General Solubility Insights

Overall, while generalizations may be drawn, the solubility of 3-(4-chlorophenyl)-1-[4-(m-tolyl)piperazin-1-yl]-3-phenyl-propan-1-one can vary widely:

  • It is likely to be more soluble in organic solvents due to its hydrophobic characteristics.
  • Solubility in water may be limited due to its bulky structure and nonpolar attributes.
  • In formulations, it may necessitate solubilizing agents or organic solvent mixtures for effective use.

In conclusion, the solubility of this compound is a complex interplay of its molecular structure and the solvent environment, making it essential to consider these factors in practical applications.

Interesting facts

Interesting Facts about 3-(4-chlorophenyl)-1-[4-(m-tolyl)piperazin-1-yl]-3-phenyl-propan-1-one

This compound, often utilized in biochemical research, belongs to a class of molecules that have shown promise in various therapeutic areas. Known for its complex structure, it offers fascinating insights into the realm of pharmacology and medicinal chemistry. Here are some notable aspects to consider:

  • Pharmacological Potential: This compound is primarily investigated for its potential as a psychotropic agent, indicating its possible use in treating disorders such as depression or anxiety.
  • Structure-Activity Relationship: The intricate arrangement of its substituents—including p-chlorophenyl and m-tolyl groups—highlights the importance of chemical structure in influencing biological activity.
  • Mechanism of Action: While the exact mechanisms remain a topic of research, it interacts with neurotransmitter systems, emphasizing the significance of molecular design in developing effective medications.
  • Research Applications: It is a valuable compound for studying receptor binding, leading to discoveries that could redefine treatment paradigms.

Overall, the study of 3-(4-chlorophenyl)-1-[4-(m-tolyl)piperazin-1-yl]-3-phenyl-propan-1-one not only enhances our understanding of complex chemical interactions but also paves the way for innovative solutions in the medical field. As always, the *implications of such compounds are vast* and nurturing further research could yield surprising advancements in health sciences.

Synonyms
beta-(p-Chlorophenyl)phenethyl 4-(m-tolyl)piperazinyl ketone
23904-88-3
1-(3-(p-Chlorophenyl)-3-phenylpropionyl)-4-(m-tolyl)piperazine
KETONE, beta-(p-CHLOROPHENYL)PHENETHYL 4-(m-TOLYL)PIPERAZINYL
Piperazine, 1-(3-(p-chlorophenyl)-3-phenylpropionyl)-4-(m-tolyl)-
RefChem:350447
3-(4-chlorophenyl)-1-[4-(3-methylphenyl)piperazin-1-yl]-3-phenylpropan-1-one
DTXSID40946711