Skip to main content

Lorpiprazole

ADVERTISEMENT
Identification
Molecular formula
C26H27ClN2O
CAS number
6104-71-8
IUPAC name
3-(4-chlorophenyl)-1-[4-(o-tolyl)piperazin-1-yl]-3-phenyl-propan-1-one
State
State

Lorpiprazole is typically in a solid crystalline state at room temperature.

Melting point (Celsius)
143.00
Melting point (Kelvin)
416.15
Boiling point (Celsius)
518.68
Boiling point (Kelvin)
791.83
General information
Molecular weight
396.96g/mol
Molar mass
396.9330g/mol
Density
1.2560g/cm3
Appearence

Lorpiprazole typically appears as a solid. The compound itself can range in color, potentially being colorless or white depending on its degree of purity and form.

Comment on solubility

Solubility of 3-(4-chlorophenyl)-1-[4-(o-tolyl)piperazin-1-yl]-3-phenyl-propan-1-one

The solubility characteristics of 3-(4-chlorophenyl)-1-[4-(o-tolyl)piperazin-1-yl]-3-phenyl-propan-1-one can provide insightful information regarding its potential applications and behavior in various environments. This compound is a member of the class of organic compounds and is influenced by several factors, including:

  • Polarity: Due to the presence of aromatic rings and nitrogen atoms in its structure, the polarity of this compound plays a critical role in its solubility in different solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds can affect the interaction of the compound with polar solvents, thereby influencing its solubility profile.
  • Temperature: Solubility is often temperature-dependent; thus, as temperature increases, the solubility of the compound in solvents may also change.

In general, compounds with these structural features may exhibit limited solubility in water but could dissolve more readily in organic solvents such as ethanol or dimethyl sulfoxide (DMSO). Additionally, it is important to note that:

  • The solubility can vary significantly based on the presence of functional groups.
  • Interactions with other substances can create different solubility behaviors.

Thus, understanding the solubility of 3-(4-chlorophenyl)-1-[4-(o-tolyl)piperazin-1-yl]-3-phenyl-propan-1-one is essential for its effective utilization in laboratory and industrial settings.

Interesting facts

Interesting Facts about 3-(4-Chlorophenyl)-1-[4-(o-tolyl)piperazin-1-yl]-3-phenyl-propan-1-one

This compound is a fascinating example of a synthetic organic molecule with significant implications in the field of pharmaceuticals. Known for its multi-ring structure and specific functional groups, it showcases the complexity and artistry inherent in chemical synthesis.

Key Characteristics:

  • Pharmacological Relevance: This molecule is often explored in the context of its potential therapeutic effects, particularly in treating neurological and psychological disorders due to its interaction with various neurotransmitter systems.
  • Chlorophenyl Group: The presence of a 4-chlorophenyl moiety not only enhances the compound's lipophilicity but also may contribute to its activity by mimicking natural neurotransmitters.
  • Piperazine Core: The piperazine ring present in this compound is a common scaffold for many anti-anxiety and antidepressant drugs, further underlining its significance in medicinal chemistry.

Moreover, the varying substituents on the piperazine and phenyl groups provide a rich field for structure-activity relationship (SAR) studies, making it an exciting target for researchers. As scientists delve deeper into the characterization of such compounds, they often discover unexpected interactions and effects that can lead to novel therapeutic agents.

In the world of drug design, compounds like this often embody the fine balance between potency and selectivity, urging chemists to innovate continually. The journey of synthesizing and understanding such compounds is what sustains excitement in the field of chemistry.

To quote a renowned chemist, “In every molecule lies a story waiting to be told,” and this compound certainly adds a captivating chapter to the narrative of pharmacological development.

Synonyms
23904-87-2
beta-(p-Chlorophenyl)phenethyl 4-(o-tolyl)piperazinyl ketone
1-(3-(p-Chlorophenyl)-3-phenylpropionyl)-4-(o-tolyl)piperazine
KETONE, beta-(p-CHLOROPHENYL)PHENETHYL 4-(o-TOLYL)PIPERAZINYL
Piperazine, 1-(3-(p-chlorophenyl)-3-phenylpropionyl)-4-(o-tolyl)-
RefChem:350450
3-(4-chlorophenyl)-1-[4-(2-methylphenyl)piperazin-1-yl]-3-phenylpropan-1-one
DTXSID80946710
3-(p-Chlorophenyl)-3-phenyl-1-[4-(2-methylphenyl)-1-piperazinyl]-1-propanone