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Chlorphenamidine

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Identification
Molecular formula
C9H11ClN2O2
CAS number
15862-73-8
IUPAC name
3-(4-chlorophenyl)-1-methoxy-1-methyl-urea
State
State

Chlorphenamidine is a solid at room temperature.

Melting point (Celsius)
214.00
Melting point (Kelvin)
487.15
Boiling point (Celsius)
344.10
Boiling point (Kelvin)
617.25
General information
Molecular weight
214.64g/mol
Molar mass
214.6440g/mol
Density
1.3020g/cm3
Appearence

Chlorphenamidine appears as a white or off-white crystalline powder. The compound is typically odorless.

Comment on solubility

Solubility of 3-(4-chlorophenyl)-1-methoxy-1-methyl-urea

The solubility of 3-(4-chlorophenyl)-1-methoxy-1-methyl-urea can be influenced by several factors, including temperature, solvent polarity, and molecular structure. Here are some key points to consider:

  • Polarity: This compound contains both aromatic and aliphatic components which affect its interactions with solvents. Generally, the presence of the methoxy group increases polarity.
  • Solvent Compatibility: It is likely to be more soluble in polar solvents such as methanol and ethanol due to its polar functional groups.
  • Temperature Effect: Like many organic compounds, solubility may increase with an increase in temperature, allowing for greater dissolution in solvents.
  • Concentration Limitations: There may be a specific concentration threshold, beyond which solubility dramatically decreases, often leading to precipitation.
  • Crystalline Structure: Solubility can also depend on the sample's crystallinity; more crystalline forms might exhibit lower solubility.

As noted, “the solubility of a compound is vital for its potential applications in various fields, including pharmaceuticals and agrochemicals.” Understanding the solubility characteristics of 3-(4-chlorophenyl)-1-methoxy-1-methyl-urea is essential for optimizing its use in solutions or dispersions.

Interesting facts

Interesting Facts about 3-(4-chlorophenyl)-1-methoxy-1-methyl-urea

3-(4-chlorophenyl)-1-methoxy-1-methyl-urea is a fascinating compound that has drawn the attention of chemists due to its unique structure and potential applications. Here are some key points about this compound:

  • Functional Groups: This compound contains a urea functional group, which is crucial in medicinal chemistry. Urea derivatives often exhibit biological activity and can function as important intermediates in drug synthesis.
  • Chlorophenyl Moiety: The presence of the 4-chlorophenyl group enhances the compound’s lipophilicity and can influence its interaction with biological targets, making it valuable in the search for new therapeutic agents.
  • Synthetic Versatility: The methoxy group contributes to the compound’s solubility and reactivity, allowing for further modifications and potentially leading to a variety of derivatives with distinct properties.
  • Biological Activity: Compounds similar to this one have been investigated for various biological activities, including their effects on cancer cells and as potential herbicides. This signifies the compound’s potential utility in pharmaceutical and agricultural domains.
  • Research Applications: This compound serves as a model for studying interactions in biological systems and evaluating structure-activity relationships (SAR). Such research can help chemists design more effective drugs with reduced side effects.

As one delves deeper into the world of organic chemistry, compounds like 3-(4-chlorophenyl)-1-methoxy-1-methyl-urea exemplify the intricate relationship between structure and function in chemistry. Their multifaceted nature and diverse potential applications continue to fuel research and innovation in various scientific fields.

Synonyms
MONOLINURON
1746-81-2
3-(4-Chlorophenyl)-1-methoxy-1-methylurea
Monorotox
Arezin
Arezine
Premalin
Aresin
Urea, N'-(4-chlorophenyl)-N-methoxy-N-methyl-
Caswell No. 207D
Monolinuron [BSI:ISO]
HOE 2747
Arresin
Afesin
HSDB 5030
Urea, 3-(p-chlorophenyl)-1-methoxy-1-methyl-
UNII-6KJJ4XAD6M
6KJJ4XAD6M
3-(p-Chlorophenyl)-1-methoxy-1-methylurea
N'-(4-Chlorophenyl)-N-methoxy-N-methylurea
N-(4-Chlorophenyl)-N'-methoxy-N-methylurea
EINECS 217-129-5
HOE 02747
EPA Pesticide Chemical Code 207500
BRN 2212523
DTXSID0037576
MONOLINURON [MI]
3-(4-Chlorphenyl)-1-methoxy-1-methylharnstoff
MONOLINURON [ISO]
MONOLINURON [HSDB]
3-(4-Chlorphenyl)-1-methoxy-1-methylharnstoff [German]
DTXCID8017576
1-Methoxy-1-methyl-3-(4-chlorophenyl)urea
3-(4-CHLORPHENYL)-1-METHOXY-1-METHYLHARNSTOFF (GERMAN)
3(pChlorophenyl)1methoxy1methylurea
3(4Chlorophenyl)1methoxy1methylurea
N(4Chlorophenyl)N'methoxyNmethylurea
Urea, 3(pchlorophenyl)1methoxy1methyl
Urea, N'(4chlorophenyl)NmethoxyNmethyl
3(4Chlorphenyl)1methoxy1methylharnstoff
217-129-5
lkjpsuckslormf-uhfffaoysa-n
CHEBI:81965
1-(4-chlorophenyl)-3-methoxy-3-methylurea
MFCD00055264
Monolinuron 10 microg/mL in Acetonitrile
Monolinuron 100 microg/mL in Acetonitrile
SCHEMBL65568
MLS000058831
CHEMBL1320234
HMS2402C08
BCP05312
Tox21_301360
AKOS001686898
SDCCGMLS-0013702.P002
s10380
NCGC00255518-01
DS-16467
SMR000069097
CAS-1746-81-2
CS-0151364
M3269
NS00010426
C18794
Monolinuron, PESTANAL(R), analytical standard
Q6901670