3-(4-Chlorophenyl)-1,3-benzoxazin-4-one

Identification

Molecular formula

C₁₄H₈ClNO₂

CAS number

2893-78-9

IUPAC name

3-(4-chlorophenyl)-2H-1,3-benzoxazin-4-one

State

This compound is typically found in a solid state at room temperature. It is stable under normal conditions and does not easily sublimate or evaporate.

Melting point (Celsius)

167.00

Melting point (Kelvin)

440.15

Boiling point (Celsius)

350.00

Boiling point (Kelvin)

623.15

General information

Molecular weight

259.68g/mol

Molar mass

259.6760g/mol

Density

1.3990g/cm³

Appearence

3-(4-Chlorophenyl)-2H-1,3-benzoxazin-4-one appears as a white to off-white crystalline solid. The compound's crystalline nature can often result in a slightly glossy or shiny appearance depending on the light conditions.

Comment on solubility

Solubility of 3-(4-chlorophenyl)-2H-1,3-benzoxazin-4-one

The solubility of the compound 3-(4-chlorophenyl)-2H-1,3-benzoxazin-4-one can be quite intriguing. This benzoxazinone derivative presents unique attributes that influence how it interacts with solvents. Here are some key points to consider:

Polar Nature: The presence of the chlorine atom and the benzoxazinone functional group may impart some degree of polarity to the compound, affecting its solubility in polar solvents like water and some organic solvents.
Organic Solvents: It is typically more soluble in organic solvents such as ethanol, methanol, or dimethyl sulfoxide (DMSO), which can facilitate better dissolution compared to water.
Hydrophobic Characteristics: The aromatic rings may introduce hydrophobic characteristics, potentially limiting solubility in highly polar solvents.
pH Dependence: The solubility may also be influenced by the pH of the solution, as functional groups can exist in different protonation states depending on the acidity or basicity of the environment.

In conclusion, while 3-(4-chlorophenyl)-2H-1,3-benzoxazin-4-one displays varied solubility characteristics, its solubility profile tends to be more favorable in organic solvents due to its structure and interactions. Understanding these attributes is essential for applications in various chemical and pharmaceutical processes.

Interesting facts

Exploring 3-(4-chlorophenyl)-2H-1,3-benzoxazin-4-one

The compound 3-(4-chlorophenyl)-2H-1,3-benzoxazin-4-one is a fascinating member of the benzoxazine class, known for its unique chemical structure and versatile applications. This compound has garnered attention in various fields, including organic chemistry and medicinal chemistry, due to its potential bioactive properties. Here are some interesting aspects:

Structural Characteristics: The presence of a benzoxazine ring combined with a chlorophenyl group provides significant stability and unique reactivity, making it an intriguing subject for synthetic chemists.
Potential Applications: Compounds in the benzoxazine family are frequently explored for use in:
- Pharmaceuticals - Due to their potential therapeutic effects.
- Polymers - Their ability to form thermosetting resins is widely utilized in material science.
Research Interest: The compound has been the focus of various studies aiming to elucidate its pharmacological properties. For example, its "phenolic" nature could contribute to antioxidant behavior.
Environmental Impact: The chlorophenyl group in this compound can raise concerns regarding environmental persistence and toxicity, making it essential to investigate its degradation properties in ecological studies.

In conclusion, 3-(4-chlorophenyl)-2H-1,3-benzoxazin-4-one is not just a compound with a complex structure; it is a gateway to understanding the dynamic interactions of organic compounds in both natural and synthetic environments. As research continues, we may uncover even more applications and implications of its unique properties.

Synonyms

BRN 1581221

20978-98-7

4H-1,3-BENZOXAZIN-4-ONE, 3-(p-CHLOROPHENYL)-2,3-DIHYDRO-

DTXSID40175180

3-(p-Chlorophenyl)-2,3-dihydro-4H-1,3-benzoxazin-4-one

RefChem:297036

DTXCID4097671