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3-(4-Chlorophenyl)-3-methylbutan-2-one

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Identification
Molecular formula
C11H13ClO
CAS number
66346-01-8
IUPAC name
3-(4-chlorophenyl)-3-methyl-butan-2-one
State
State

At room temperature, 3-(4-chlorophenyl)-3-methylbutan-2-one is typically in a liquid state.

Melting point (Celsius)
-35.00
Melting point (Kelvin)
238.15
Boiling point (Celsius)
260.10
Boiling point (Kelvin)
533.25
General information
Molecular weight
184.66g/mol
Molar mass
184.6610g/mol
Density
0.9856g/cm3
Appearence

3-(4-Chlorophenyl)-3-methylbutan-2-one appears as a colorless to pale yellow liquid with a characteristic aromatic odor. It is typically clear and homogenous when pure, and any turbidity may indicate impurities.

Comment on solubility

Solubility of 3-(4-chlorophenyl)-3-methyl-butan-2-one

The compound 3-(4-chlorophenyl)-3-methyl-butan-2-one, often referred to for its interesting structural features, exhibits distinct solubility characteristics that can be intriguing to analyze. Understanding its solubility is essential for applications in various fields such as organic synthesis and pharmaceutical formulations.

Key Factors Affecting Solubility:

  • Polarity: The presence of the 4-chlorophenyl group and the ketone functional group significantly influences the polarity of the molecule. This contributes to its ability to dissolve in polar solvents.
  • Solvent Interaction: It tends to be more soluble in organic solvents such as ethanol and methanol, whereas its solubility in water is limited due to its hydrophobic hydrocarbon backbone.
  • Temperature: Higher temperatures can generally improve solubility, as increased thermal energy allows more effective interactions between solute and solvent.

In summary, while 3-(4-chlorophenyl)-3-methyl-butan-2-one shows promising solubility in certain organic solvents, its overall solubility profile is dictated by its molecular structure and the characteristics of the solvent used. As always, it is crucial to consider these factors when working with this compound in various applications.

Interesting facts

Interesting Facts about 3-(4-chlorophenyl)-3-methyl-butan-2-one

3-(4-chlorophenyl)-3-methyl-butan-2-one, also known as Clonazolam, is a fascinating compound that has captured the attention of both researchers and pharmaceutical scientists. Here are some intriguing aspects:

  • Origin: This compound is part of the benzodiazepine class, which is well-known for its tranquilizing effects. Clonazolam was first synthesized in the late 1970s and has since gained interest for its psychoactive properties.
  • Mechanism of Action: Like other benzodiazepines, 3-(4-chlorophenyl)-3-methyl-butan-2-one acts by enhancing the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABAA receptor. This results in sedative, anxiolytic, and muscle relaxant effects.
  • Pharmaceutical Use: Although primarily found in research contexts, its potential therapeutic applications include treatment for anxiety disorders and sleep-related issues. However, its use must be approached with caution due to the risk of dependency.
  • Legal Status: The legal status of Clonazolam varies significantly across countries. As research chemicals, many analogs of benzodiazepines have been controlled or banned in several jurisdictions owing to concerns about misuse and health risks.
  • Research Developments: Ongoing studies are investigating the safety profiles and pharmacological properties of Clonazolam and other similar compounds, aiming to better understand their therapeutic potential and risks.

In summary, while 3-(4-chlorophenyl)-3-methyl-butan-2-one may be an intriguing compound with potential medicinal benefits, it also raises important questions about safety, regulation, and long-term health impacts. As Winston Churchill once said, "To each, there comes in their lifetime a special moment when they are figuratively tapped on the shoulder and offered the chance to do a very special thing...". In this context, the study of such compounds provides a unique opportunity for scientific discovery.

Synonyms
16703-39-2
2-BUTANONE, 3-(p-CHLOROPHENYL)-3-METHYL-
BRN 1868078
2-Methyl-2-(p-chlorophenyl)-3-butanone
3-(p-Chlorophenyl)-3-methyl-2-butanone
DTXSID70168222
DTXCID9090713
3-(4-chlorophenyl)-3-methylbutan-2-one
2-Butanone, 3-(4-chlorophenyl)-3-methyl-
3-(4-chlorophenyl)-3-methyl-2-butanone
SCHEMBL3413489
BVYURCFIUPFFDK-UHFFFAOYSA-N
DA-25179
EN300-2006565